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Use of a generic violet light in the surgical management of medication-related osteonecrosis of the jaws: a technical note

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Abstract

Purpose

Fluorescence-guided surgery has been recommended for the diagnosis of bone margins in cases of mandibular osteonecrosis. In this article, we report a case in which a generic violet light was used in order to activate bone fluorescence after the administration of tetracycline derivatives, as an alternative to a specific, more expensive equipment that is commercially available for this purpose. The patient had been using alendronate for osteoporosis, resulting in medication-related osteonecrosis of the jaws.

Methods

The treatment protocol includes preoperative administration of doxycycline and the application of a generic violet light during surgery in order to observe the fluorescence of bone in response to excitation through the light emitted by this device.

Results

With an effective visualization of the limit between healthy and devitalized bone tissue, it was possible to perform the necrotic tissue removal. The lesion regressed from stage 2 to stage 0, with no clinical or radiographic evidence of necrotic bone.

Conclusions

These results suggest the feasibility of using a generic violet light source as a low-cost alternative for fluorescence-guided surgery.

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Acknowledgements

We thank Dr. Edson Laureto, PhD (Department of Physics, Laboratory of Optics and Optoelectronics, State University of Londrina) for testing the wavelength of the violet light used for the procedure.

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Authors and Affiliations

  1. Oral and Maxillofacial Surgery Residency, State University of Londrina, Londrina, Brazil

    Caroline Ballardin & Glaykon Alex Vitti Stabile

  2. Oral and Maxillofacial Surgery, State University of Londrina, Londrina, Brazil

    Cecilia Luiz Pereira-Stabile

  3. Department of Oral Medicine and Pediatric Dentistry, State University of Londrina, Rodovia Celso Garcia Cid, PR 445 Km 380, Campus Universitário, Londrina, PR, CEP 86.057-970, Brazil

    Glaykon Alex Vitti Stabile

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  1. Caroline Ballardin
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  2. Cecilia Luiz Pereira-Stabile
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Correspondence to Glaykon Alex Vitti Stabile.

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The authors declare that they have no conflict of interest.

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Informed consent was obtained from all individual participants included in the study.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.This article does not contain any studies with animals performed by any of the authors.

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Ballardin, C., Pereira-Stabile, C.L. & Stabile, G.A.V. Use of a generic violet light in the surgical management of medication-related osteonecrosis of the jaws: a technical note. Oral Maxillofac Surg 22, 477–481 (2018). https://doi.org/10.1007/s10006-018-0718-6

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  • DOI: https://doi.org/10.1007/s10006-018-0718-6

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