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Is conservative surgery a better choice for the solid/multicystic ameloblastoma than radical surgery regarding recurrence? A systematic review

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Abstract

Purpose

Determine if conservative surgery of primary solid/multicystic ameloblastoma (SMA) is capable of decreasing the recurrence rate as effectively as radical surgery.

Methods

We searched in MEDLINE, Web of Science, Scopus and Cochrane Library for original studies reporting on the conservative or radical treatment of primary SMA and the related recurrence rate. All selected data were independently assessed. Meta-analysis was performed and the Relative Risk (RR) of recurrence with a confidence interval of 95% was the effect measure. P value for the summary effect of < 0.05 was considered statistically significant.

Results

The 2647 records retrieved were reduced to 7 studies to be qualitatively assessed and 4 studies were included in the meta-analysis. RR of 1.88 [0.59, 5.95] of the pooled values pointed that recurrence rate after the conservative surgery is neither comparable nor lower than the radical surgery (P = 0.28).

Conclusions

Conservative surgery does not reduce the recurrence rate as efficiently as radical surgery for primary SMA. However, there is not enough evidence to support this statement.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Traumatology and Prosthesis - Faculty of Dentistry of the University of São Paulo, Av Prof. Lineu Prestes 2227 Butantã, São Paulo, 05508-000, Brazil

    Yuri Slusarenko da Silva, Natalia Aguiar Tartaroti, Daniel Isaac Sendyk, Maria Cristina Zindel Deboni & Maria da Graça Naclério-Homem

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  1. Yuri Slusarenko da Silva
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  2. Natalia Aguiar Tartaroti
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Correspondence to Yuri Slusarenko da Silva.

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Slusarenko da Silva, Y., Tartaroti, N.A., Sendyk, D.I. et al. Is conservative surgery a better choice for the solid/multicystic ameloblastoma than radical surgery regarding recurrence? A systematic review. Oral Maxillofac Surg 22, 349–356 (2018). https://doi.org/10.1007/s10006-018-0715-9

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  • DOI: https://doi.org/10.1007/s10006-018-0715-9

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