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Oral manifestations of HIV/AIDS in China: a review

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Abstract

Purpose

The purpose of this study is to review the Chinese-language medical and dental literature from 1982 to 2008 on oral manifestations (OMs) of patients with HIV/AIDS for introducing the spectrum of OMs of the patients in China.

Materials and methods

All data were extracted from 18 references which had used diagnostic criteria for HIV/AIDS. Four of the references had used the EC-Clearinghouse classification for oral lesions in HIV infection. The feasible overall rate and 95% confidence interval (95%CI) of the data on OMs were calculated.

Results

Risk group analysis revealed that, of 203 patients, 64.3% were men and 35.7% were women (age range, 5 months to 64 years; mean age in three studies, 34.0, 34.3, and 36.1 years). Of these patients, 22.2% were infected by sexual contacts, 11.8% by intravenous drug use (IDU), 59.6% by blood or its products, 2.9% by mother to child transmission, and 3.4% were unclear. In 203 patients, oral candidiasis (OC) was the most common lesion (66%, 95%CI = 59.48–72.52%), followed by herpes simplex (HS) (22.2%, 95%CI = 16.48–27.92%), ulcerative stomatitis (14.8%, 95%CI = 9.92–19.68%), salivary gland disease (11.3%, 95%CI = 6.94–15.66%), oral hairy leukoplakia (OHL) (9.8%, 95%CI = 5.71–13.89%), necrotizing gingivitis (5.9%, 95%CI = 2.66–9.14%), Kaposi’s sarcoma (2.9%, 95%CI = 0.59–5.21%), other malignant tumors (2.9%, 95%CI = 0.59–5.21%), and linear gingival erythema (2.0%, 95%CI = 0.07–3.93%).

Conclusions

The spectrum of OMs reported from China is similar to that described in the international literature. Present data are useful to supplement international resources of HIV/AIDS research.

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Authors and Affiliations

  1. Department of Oral Biology, School and Hospital of Stomatology, Peking University, Zhongguancun Nandajie 22, Beijing, 100081, People’s Republic of China

    Xiaolin Zhang

  2. Department of Oral Surgery and Stomatology, University of Bern, Bern, Switzerland

    Peter A. Reichart

  3. School of Public Health, Peking University, Beijing, People’s Republic of China

    Yi Song

Authors
  1. Xiaolin Zhang
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  2. Peter A. Reichart
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  3. Yi Song
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Corresponding author

Correspondence to Xiaolin Zhang.

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Zhang, X., Reichart, P.A. & Song, Y. Oral manifestations of HIV/AIDS in China: a review. Oral Maxillofac Surg 13, 63–68 (2009). https://doi.org/10.1007/s10006-009-0157-5

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