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Adherence and psychopathology in children and adolescents with cystic fibrosis

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Abstract

Background

The striking increase in the lifespan of individuals with cystic fibrosis (CF) has largely been attributed to the dramatic improvements in treatment regimens. These treatments are time intensive and may interfere with healthy development and family function. The objective of this study was to investigate the association between psychopathology and treatment adherence in children and adolescents with CF.

Methods

Structured psychiatric interviews were performed on 52 patients with CF. Additional information on family function and youth behaviors were also collected. Youth and parent reports of adherence to the CF treatments were obtained and compared with the CF teams’ records.

Results

The mean overall adherence to the CF teams’ recommendations was 77–81% for the child and parent reports, respectively. Children with anxiety disorders and families who were more cohesive showed significantly higher rates of adherence to the CF treatments. In addition, children in families with a balance of structure and flexibility also report higher levels of adherence to the CF treatments.

Conclusions

Anxiety disorders in children with CF may be associated with increased adherence to the numerous CF treatment regimens. In addition, family patterns that are cohesive and balanced are better able to incorporate the CF treatments into family life.

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Abbreviations

CF:

Cystic fibrosis

CPT:

Chest physical therapy

CCFMP:

Confidential cystic fibrosis management profile

FACES II:

Family adaptability and cohesion evaluation scale

C-DISC:

Computerized diagnostic inventory schedule for children

CBCL:

Child behavior checklist

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Authors and Affiliations

  1. Division of Child and Adolescent Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN, 55454, USA

    Tonya White MD

  2. Division of Child and Adolescent Psychiatry, University of Utah, 50 North Medical Drive, Salt Lake City, UT, 84112, USA

    Judith Miller PhD &  William M. McMahon MD

  3. National Research Institute, 14100 Crawford St., Boys Town, NE, 68010, USA

    Gail L. Smith BS

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  1. Tonya White MD
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Correspondence to Tonya White MD.

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White, T., Miller, J., Smith, G.L. et al. Adherence and psychopathology in children and adolescents with cystic fibrosis. Eur Child Adolesc Psychiatry 18, 96–104 (2009). https://doi.org/10.1007/s00787-008-0709-5

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