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REM-sleep alterations in children with co-existence of tic disorders and attention-deficit/hyperactivity disorder: impact of hypermotor symptoms

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Abstract

Purpose

To characterize precisely the sleep pattern in children with co-existence of TD + ADHD.

Methods

By means of polysomnography, sleep pattern was investigated in 19 children with TD + ADHD unmedicated before and during study and 19 healthy controls, matched for age, gender, and intelligence.

Results

Compared with healthy controls, children with TD + ADHD displayed shorter REM sleep latency and increased REM sleep duration. There was a negative correlational relationship between these REM-sleep alterations and they were determined by hyperactivity symptoms.

Conclusions

Sleep in children with coexistence of TD + ADHD may be characterized by an elevated REM sleep drive. Common mechanisms are suggested to underpin hypermotor symptoms and REM sleep regulation.

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Acknowledgments

This study was supported by the German Foundation for Scientific Research (DFG) grants 436 BUL 112/4/02 and 436 BUL 112/35/03. We are very thankful to Drs. S. Cohrs, G. Hajak, and W. Woerner for their helpful advice.

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Authors and Affiliations

  1. Institute of Physiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str. 23, 1113, Sofia, Bulgaria

    Roumen Kirov

  2. Child and Adolescent Psychiatry, University of Goettingen, Von Siebold-Str. 5, 37075, Goettingen, Germany

    Tobias Banaschewski, Henrik Uebel, Jörg Kinkelbur &  Aribert Rothenberger

Authors
  1. Roumen Kirov
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  2. Tobias Banaschewski
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  3. Henrik Uebel
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  4. Jörg Kinkelbur
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  5. Aribert Rothenberger
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Corresponding author

Correspondence to Aribert Rothenberger.

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Kirov, R., Banaschewski, T., Uebel, H. et al. REM-sleep alterations in children with co-existence of tic disorders and attention-deficit/hyperactivity disorder: impact of hypermotor symptoms. Eur Child Adolesc Psychiatry 16 (Suppl 1), 45–50 (2007). https://doi.org/10.1007/s00787-007-1006-4

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