Abstract
Objectives
This multicenter study aimed to evaluate the effects of St. John’s wort oil and virgin olive oil on the postoperative complications and compare this with chlorhexidine gluconate plus benzydamine hydrochloride mouthwash after the removal of impacted third molar.
Methods
A total of 90 patients in need of impacted third molar surgery were included in this study. All included patients were randomly divided into 3 groups. The patients in group 1 received St. John’s wort oil; the patients in group 2 received virgin olive oil, and those in group 3 received mouthwash containing chlorhexidine gluconate plus benzydamine hydrochloride. The self-reported pain and difficulty during jaw function, trismus, facial swelling, number of analgesics used during first postoperative week, and postoperative periodontal condition including plaque accumulation, bleeding on probing, and periodontal pocket depth were compared between the groups.
Results
No significant differences were found regarding the study variables.
Conclusions
The data of the present study supports that the use of essential oils provides efficient alternative to the gold standard chlorhexidine gluconate mouthwash in reducing postoperative complications and improving healing process without adverse effects after surgical removal of impacted third molars.
Clinical relevance
The use of essential oils showed similar results as the chlorhexidine gluconate mouthwash regarding swelling, mouth opening, pain, need for rescue medication, infectious complications (i.e., alveolar osteitis), and periodontal healing. Therefore, essential oils can be an alternative to routine mouthwashes to ensure oral hygiene after impacted third molar surgery.
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Guzin Neda Hasanoglu Erbasar conceptualized and designed the study. Data acquisition was performed by Volkan Kaplan, Guzin Neda Hasanoglu Erbasar, Levent Cigerim, and Hilal Altay Turgut. The analysis was performed by Abdullah Cerit. The manuscript was drafted by Volkan Kaplan, Guzin Neda Hasanoglu Erbasar, Levent Cigerim, Hilal Altay Turgut, and Abdullah Cerit.
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All procedures performed in this study involving human participants were in accordance with the ethical standards of the ethical committee of the University of Granada and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Informed consent was obtained from all individual participants included in the study.
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Kaplan, V., Hasanoglu Erbasar, G.N., Cigerim, L. et al. Effect of St. John’s wort oil and olive oil on the postoperative complications after third molar surgery: randomized, double-blind clinical trial. Clin Oral Invest 25, 2429–2438 (2021). https://doi.org/10.1007/s00784-020-03639-0
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DOI: https://doi.org/10.1007/s00784-020-03639-0