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Periodontitis and the impact of oral health on the quality of life of psoriatic individuals: a case-control study

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Abstract

Aim

To evaluate the periodontal condition and the impact of oral health on the quality of life (OHRQL) among individuals with and without psoriasis.

Methods

This case-control study comprised 295 individuals with psoriasis and 359 controls. A full mouth examination was performed for all periodontal clinical parameters. To evaluate OHRQL, the Oral Impact on Daily Performance (OIDP) questionnaire was applied. Data was analyzed using the chi-square, Fischer, Kruskal–Wallis, Mann–Whitney, and Bootstrap intervals tests to determine different profiles in relation to the OIDP.

Results

Individuals with psoriasis had a 1.40 greater chance of having periodontitis than controls (OR = 1.40 95%CI: 1.01–1.93; p = 0.019). Individuals with psoriasis with periodontitis (+P) had greater impacts on OHRQL (13.76 ± 15.58), when compared with those without periodontitis (−P) (4.83 ± 8.25; p < 0.001). Additionally, psoriasis +P stage III/IV patients (13.94 ± 15.68) had worse indicators than controls −P (9.49 ± 22.54; p = 0.001). The final multivariate model demonstrated higher OIDP scores related to the following variables: diabetes, anxiolytics use, periodontitis, and psoriasis, showing worse OHRQoL.

Conclusions

This study demonstrated an important risk association between psoriasis and periodontitis, as both diseases demonstrated worse OHRQL indicators. Moreover, the severity of periodontitis and psoriasis significantly increased these negative impacts.

Clinical relevance

Practical implications: Multidisciplinary interaction is desirable to improve the impact of these diseases on the QoL of individuals with psoriasis and periodontitis.

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References

  1. Linden GJ, Lyons A, Scannapieco FA (2013) Periodontal systemic associations: review of the evidence. J Clin Periodontol 40:S8–S19. https://doi.org/10.1111/jcpe.12064

    Article  PubMed  Google Scholar 

  2. Ungprasert P, Wijarnpreecha K, Wetter DA (2017) Periodontitis and risk of psoriasis: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol 31:857–862. https://doi.org/10.1111/jdv.14051

    Article  PubMed  Google Scholar 

  3. Christophers E (2001) Psoriasis-epidemiology and clinical spectrum. Clin Exp Dermatol 26:314–320 http://www.ncbi.nlm.nih.gov/pubmed/11422182 (accessed June 12, 2018)

    Article  Google Scholar 

  4. Boehncke W, Schön MP (2015) Psoriasis. Lancet. 386:983–994. https://doi.org/10.1016/S0140-6736(14)61909-7

    Article  PubMed  Google Scholar 

  5. Rapp SR, Feldman SR, Exum ML, Fleischer AB, Reboussin DM (1999) Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 41:401–407. https://doi.org/10.1016/S0190-9622(99)70112-X

    Article  PubMed  Google Scholar 

  6. Brooks JK (2018) Psoriasis: a review of systemic comorbidities and dental management considerations. Quintessence Int 49:209–217. https://doi.org/10.3290/j.qi.a39692

    Article  PubMed  Google Scholar 

  7. Griffiths CE, Barker JN (2007) Pathogenesis and clinical features of psoriasis. Lancet. 370:263–271. https://doi.org/10.1016/S0140-6736(07)61128-3

    Article  PubMed  Google Scholar 

  8. Nestle FO, Kaplan DH, Barker J (2009) Psoriasis. N Engl J Med 361:496–509. https://doi.org/10.1056/NEJMra0804595

    Article  PubMed  Google Scholar 

  9. Egeberg A, Mallbris L, Gislason G, Hansen PR, Mrowietz U (2017) Risk of periodontitis in patients with psoriasis and psoriatic arthritis. J Eur Acad Dermatology Venereol 31:288–293. https://doi.org/10.1111/jdv.13814

    Article  Google Scholar 

  10. Fadel HT, Flytström I, Calander A-M, Bergbrant I-M, Heijl L, Birkhed D (2013) Profiles of dental caries and periodontal disease in individuals with or without psoriasis. J Periodontol 84:477–485. https://doi.org/10.1902/jop.2012.120119

    Article  PubMed  Google Scholar 

  11. Mendes VS, Cota LOM, Costa AA, Oliveira AMSD, Costa FO (2018) Periodontitis as another comorbidity associated with psoriasis: a case-control study. J Periodontol 90:1–9. https://doi.org/10.1002/JPER.18-0394

    Article  Google Scholar 

  12. Preus HR, Khanifam P, Kolltveit K, Mørk C, Gjermo P (2010) Periodontitis in psoriasis patients: a blinded, case-controlled study. Acta Odontol Scand 68:165–170. https://doi.org/10.3109/00016350903583678

    Article  PubMed  Google Scholar 

  13. Sharma A, Raman A, Pradeep A (2015) Association of chronic periodontitis and psoriasis: periodontal status with severity of psoriasis. Oral Dis 21:314–319. https://doi.org/10.1111/odi.12271

    Article  PubMed  Google Scholar 

  14. Su N-Y, Huang J-Y, Hu C-J, Yu H-C, Chang Y-C (2017) Increased risk of periodontitis in patients with psoriatic disease: a nationwide population-based retrospective cohort study. Peer J 5:e4064. https://doi.org/10.7717/peerj.4064

    Article  PubMed  Google Scholar 

  15. Adulayon S, Sheiham A (1997) Measuring Oral Health and Quality of Life

  16. Adulyanon S, Vourapukjaru J, Sheiham A (1996) Oral impacts affecting daily performance in a low dental disease Thai population. Community Dent Oral Epidemiol 24:385–389. https://doi.org/10.1111/j.1600-0528.1996.tb00884.x

    Article  PubMed  Google Scholar 

  17. El Sayed N, Baeumer A, El Sayed S, Wieland L, Weber D, Eickholz P, Pretzl B (2019) Twenty years later: oral health-related quality of life and standard of treatment in patients with chronic periodontitis. J Periodontol 90:323–330. https://doi.org/10.1002/JPER.18-0417

    Article  PubMed  Google Scholar 

  18. Locker D, Allen F (2007) What do measures of “oral health-related quality of life” measure? Community Dent Oral Epidemiol 35:401–411. https://doi.org/10.1111/j.1600-0528.2007.00418.x

    Article  PubMed  Google Scholar 

  19. Tsakos G, Bernabé E, D’Aiuto F, Pikhart H, Tonetti M, Sheiham A, Donos N (2010) Assessing the minimally important difference in the Oral Impact on Daily Performances index in patients treated for periodontitis. J Clin Periodontol 37:903–909. https://doi.org/10.1111/j.1600-051X.2010.01583.x

    Article  PubMed  Google Scholar 

  20. Costa FO, Guimarães AN, Cota LOM, Pataro AL, Segundo TK, Cortelli SC, Costa JE (2009) Impact of different periodontitis case definitions on periodontal research. J Oral Sci 51:199–206. https://doi.org/10.2334/josnusd.51.199

    Article  PubMed  Google Scholar 

  21. Cunha-Cruz J, Hujoel PP, Kressin NR (2007) Oral health-related quality of life of periodontal patients. J Periodontal Res 42:169–176. https://doi.org/10.1111/j.1600-0765.2006.00930.x

    Article  PubMed  Google Scholar 

  22. Needleman I, McGrath C, Floyd P, Biddle A (2004) Impact of oral health on the life quality of periodontal patients. J Clin Periodontol 31:454–457. https://doi.org/10.1111/j.1600-051X.2004.00498.x

    Article  PubMed  Google Scholar 

  23. Santuchi CC, Cortelli JR, Cortelli SC, Cota LOM, Fonseca DC, Alencar CO, Costa FO (2016) Scaling and root planing per quadrant versus one-stage full-mouth disinfection: assessment of the impact of chronic periodontitis treatment on quality of life — a clinical randomized, controlled trial. J Periodontol 87:114–123. https://doi.org/10.1902/jop.2015.150105

    Article  PubMed  Google Scholar 

  24. Yokoyama K, Sugano N, Shimada T, Shofiqur RAKM, Ibrahim E-SM, Isoda R, Umeda K, Van Sa N, Kodama Y, Ito K (2007) Effects of egg yolk antibody against Porphyromonas gingivalis gingipains in periodontitis patients. J Oral Sci 49:201–206 http://www.ncbi.nlm.nih.gov/pubmed/17928726 (accessed March 27, 2019)

    Article  Google Scholar 

  25. Abegg C, Fontanive VN, Tsakos G, Davoglio RS, de Oliveira MMC (2015) Adapting and testing the Oral Impacts on Daily Performances among adults and elderly in Brazil. Gerodontology. 32:46–52. https://doi.org/10.1111/ger.12051

    Article  PubMed  Google Scholar 

  26. Silness J, Löe H (1964) Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 22:121–135. https://doi.org/10.3109/00016356408993968

    Article  PubMed  Google Scholar 

  27. Tonetti MS, Greenwell H, Kornman KS (2018) Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin Periodontol 45:S149–S161. https://doi.org/10.1111/jcpe.12945

    Article  Google Scholar 

  28. Fredriksson T, Pettersson U (1978) Severe psoriasis--oral therapy with a new retinoid. Dermatologica. 157:238–244 http://www.ncbi.nlm.nih.gov/pubmed/357213 (accessed October 30, 2018)

    Article  Google Scholar 

  29. ADA (2018) Classification and diagnosis of diabetes: standards of medical care in diabetesd 2018. Diabetes Care 41:S13–S27. https://doi.org/10.2337/dc18-S002

    Article  Google Scholar 

  30. Tomar SL, Asma S (2000) Smoking-attributable periodontitis in the United States: findings from NHANES III. J Periodontol 71:743–751. https://doi.org/10.1902/jop.2000.71.5.743

    Article  PubMed  Google Scholar 

  31. Keller JJ, Lin H-C (2012) The effects of chronic periodontitis and its treatment on the subsequent risk of psoriasis. Br J Dermatol 167:1338–1344. https://doi.org/10.1111/j.1365-2133.2012.11126.x

    Article  PubMed  Google Scholar 

  32. Lazaridou E, Tsikrikoni A, Fotiadou C, Kyrmanidou E, Vakirlis E, Giannopoulou C, Apalla Z, Ioannides D (2013) Association of chronic plaque psoriasis and severe periodontitis: a hospital based case-control study. J Eur Acad Dermatol Venereol 27:967–972. https://doi.org/10.1111/j.1468-3083.2012.04615.x

    Article  PubMed  Google Scholar 

  33. Nakib S, Han J, Li T, Joshipura K, Qureshi AA (2013) Periodontal disease and risk of psoriasis among nurses in the United States. Acta Odontol Scand 71:1423–1429. https://doi.org/10.3109/00016357.2013.766360

    Article  PubMed  PubMed Central  Google Scholar 

  34. Chainani SH, Manjunathappa TH (2014) Antiplaque and antigingivitis effi cacy of triphala and chlorhexidine mouthrinse among schoolchildren – A. 12:209–217. https://doi.org/10.3290/j.ohpd.a32674

  35. Ungprasert P, Wijarnpreecha K, Wetter D (2017) Periodontitis and risk of psoriasis : a systematic review and. J Eur Acad Dermatol Venereol 31:857–862. https://doi.org/10.1111/jdv.14051

    Article  PubMed  Google Scholar 

  36. Woeste S, Graetz C, Gerdes S, Mrowietz U (2019) Oral health in patients with psoriasis — a prospective study. J Invest Dermatol 139:1–8. https://doi.org/10.1016/j.jid.2018.12.014

    Article  Google Scholar 

  37. Ebersole JL (2003) Humoral immune responses in gingival crevice fluid: local and systemic implications. Periodontol. 2000(31):135–166 http://www.ncbi.nlm.nih.gov/pubmed/12657000 (accessed June 12, 2018)

    Article  Google Scholar 

  38. Sabat R, Philipp S, Höflich C, Kreutzer S, Wallace E, Asadullah K, Volk H-D, Sterry W, Wolk K (2007) Immunopathogenesis of psoriasis. Exp Dermatol 16:779–798. https://doi.org/10.1111/j.1600-0625.2007.00629.x

    Article  PubMed  Google Scholar 

  39. Jensen P, Skov L (2017) Psoriasis and obesity. Dermatology. 232:633–639. https://doi.org/10.1159/000455840

    Article  Google Scholar 

  40. Dowlatshahi EA, Wakkee M, Arends LR, Nijsten T (2014) The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: a systematic review and meta-analysis. J Invest Dermatol 134:1542–1551. https://doi.org/10.1038/jid.2013.508

    Article  PubMed  Google Scholar 

  41. Langley RGB, Krueger GG, Griffiths CEM (2005) Psoriasis: epidemiology, clinical features, and quality of life. Ann Rheum Dis 64:18–23. https://doi.org/10.1136/ard.2004.033217

    Article  Google Scholar 

  42. Ẑarkovi Palijan T, Kovaevi D, Vlastelica M, Dadi-Hero E, Sarilar M (2017) Quality of life of persons suffering from schizophrenia, psoriasis and physical disabilities. Psychiatr Danub 29:60–65. https://doi.org/10.24869/psyd.2017.60

    Article  PubMed  Google Scholar 

  43. Salman A, Yucelten AD, Sarac E, Saricam MH, Perdahli-fis N (2018) Impact of psoriasis in the quality of life of children, adolescents and their families: a cross-sectional study. Ann Bras Dermatology 93:819–823

    Article  Google Scholar 

  44. Al-Harthi LS, Cullinan MP, Leichter JW, Thomson WM (2013) The impact of periodontitis on oral health-related quality of life: a review of the evidence from observational studies. Aust Dent J 58:274–277; quiz 384. https://doi.org/10.1111/adj.12076

    Article  PubMed  Google Scholar 

  45. de Freitas Borges T, Regalo SC, Taba M, Siéssere S, Mestriner W, Semprini M (2013) Changes in masticatory performance and quality of life in individuals with chronic periodontitis. J Periodontol 84:325–331. https://doi.org/10.1902/jop.2012.120069

    Article  Google Scholar 

  46. Llanos AH, Benítez Silva CG, Ichimura KT, Rebeis ES, Giudicissi M, Romano MM, Saraiva L (2018) Impact of aggressive periodontitis and chronic periodontitis on oral health-related quality of life. Braz Oral Res 32:e006. https://doi.org/10.1590/1807-3107bor-2018.vol32.0006

    Article  PubMed  Google Scholar 

  47. Wandera MN, Engebretsen IM, Rwenyonyi CM, Tumwine J, Åstrøm AN (2009) Periodontal status, tooth loss and self-reported periodontal problems effects on Oral Impacts on Daily Performances, OIDP, in pregnant women in Uganda: A cross-sectional study. Health Qual Life Outcomes 7:89. https://doi.org/10.1186/1477-7525-7-89

    Article  PubMed  PubMed Central  Google Scholar 

  48. Talaee R, Hajheydari Z, Moghaddam AY, Moraveji SA, Ravandi BF (2017) Prevalence of oral mucosal lesions and their association with severity of psoriasis among psoriatic patients referred to dermatology clinic: a cross-sectional study in Kashan/Iran. Open Acecss Maced J Med Sci 15:978–982. https://doi.org/10.3889/oamjms.2017.189

    Article  Google Scholar 

  49. Cabras M, Gambino A, Broccoletti R, Lodi G, Arduino PG (2020) Treatment of angular cheilitis: a narrative review and authors’ clinical experience. Oral Dis 26:1107–1115. https://doi.org/10.1111/odi.13183

    Article  Google Scholar 

  50. Hernandez-Perez F, Jaimes-Aveldañez A, Urquizo-Ruvalcaba M, Díaz-Barcelot M, Camacho-Irigoyen ME, Veja-Memije ME, Mosqueda-Taylor A (2008) Prevalence of oral lesions in patients with psoriasis. Med Oral Patol Oral Cir Bucal 13:E703–E708

    PubMed  Google Scholar 

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Funding

This study was supported by the National Council of Scientific and Technological Development – CNPq, Brazil grants (#430074/2018-2) and Productivity research (# 303447/2016-8).

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Authors and Affiliations

  1. Department of Dental Clinics, Oral Pathology, and Oral Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

    Amanda Almeida Costa, Luís Otávio Miranda Cota, Victor Silva Mendes, Renata Magalhães Cyrino & Fernando Oliveira Costa

  2. Pontific Catholic University of Minas Gerais, Belo Horizonte, Minas Gerais, 31270-901, Brazil

    Alcione Maria Soares Dutra Oliveira

  3. Faculty of Dentistry, Department of Periodontology, Federal University of Minas Gerais, Antônio Carlos Avenue, 6627, Pampulha, Belo Horizonte, Minas Gerais, 31270-901, Brazil

    Fernando Oliveira Costa

Authors
  1. Amanda Almeida Costa
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  2. Luís Otávio Miranda Cota
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  3. Victor Silva Mendes
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  4. Alcione Maria Soares Dutra Oliveira
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  6. Fernando Oliveira Costa
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Contributions

All authors have made substantial contributions to conception and design of the study. AAC, VSM, and FOC have been involved in data collection and data analysis. AAC, VSM, LOMC, AMSDO, RMC, and FOC have been involved in data interpretation, drafting the manuscript, and revising it critically and have given final approval of the version to be published.

Corresponding author

Correspondence to Fernando Oliveira Costa.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Costa, A.A., Cota, L.O.M., Mendes, V.S. et al. Periodontitis and the impact of oral health on the quality of life of psoriatic individuals: a case-control study. Clin Oral Invest 25, 2827–2836 (2021). https://doi.org/10.1007/s00784-020-03600-1

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