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Clinical, double blind, randomized controlled trial of experimental adhesive protocols in caries-affected dentin

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Abstract

Objective

To evaluate the clinical performance of posterior resin composite restorations regarding experimental and regular adhesive protocols in caries affected-dentin (CAD).

Material and methods

A total of 92 class I and class II cavities with carious lesions were selected and randomly assigned to the following groups: (1) bioactive glass-ceramic powder/two-step etch and rinse system, (2) control/two-step etch and rinse system, (3) bioactive glass-ceramic powder/two-step self-etching system, and (4) control/two-step self-etching system. Two operators carried out the adhesive protocols and restored the cavities with a nano-hybrid resin composite. Participants were followed up at 1 week and 6, 12, and 18 months for clinical evaluation performed by two blinded examiners and calibrated according to FDI criteria. Data were analyzed using Kruskal-Wallis and Dunn tests with a confidence of 95%.

Results

The clinical performance of resin composite restoration was not affected by the experimental use of an adhesive protocol including a bioactive glass-ceramic powder for 18 months post-procedure. However, there was a significant difference between group 2 and group 4 (p < 0.05) for marginal adaptation (18 months). Group 2 was significantly different from group 3 (p < 0.05) for fracture of material/retention (18 months) and marginal adaptation (1 week); group 2 showed a better performance.

Conclusion

Adhesive protocols can alter the clinical performance of posterior restorations in terms of marginal adaptation and the fracture of material/retention in CAD. Clinical significance: Adhesive protocols may influence the success of resin composite restorations in CAD; this is important because failure can lead to caries, re-incidence, and/or clinical re-work.

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Funding

This study was funded by the São Paulo Research Foundation - FAPESP (grant number 2010/12032-6) and Center for Research, Teaching and Innovation in Glass (CeRTEV)/CEPID grant number 2013/07793-6.

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Authors and Affiliations

  1. Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café sn, Bairro Monte Alegre, São Paulo, 14040-904, Brazil

    Karen Pintado-Palomino, Cecilia Vilela Vasconcelos Barros de Almeida, Raphael Jurca Gonçalves da Motta, João Henrique Parise Fortes & Camila Tirapelli

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  1. Karen Pintado-Palomino
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  2. Cecilia Vilela Vasconcelos Barros de Almeida
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  3. Raphael Jurca Gonçalves da Motta
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  5. Camila Tirapelli
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Correspondence to Karen Pintado-Palomino.

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All procedures performed in studies involving human participants were conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Pintado-Palomino, K., de Almeida, C.V.V.B., da Motta, R.J.G. et al. Clinical, double blind, randomized controlled trial of experimental adhesive protocols in caries-affected dentin. Clin Oral Invest 23, 1855–1864 (2019). https://doi.org/10.1007/s00784-018-2615-7

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