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The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women

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Abstract

Objectives

The aim of this study was to assess the determinants of oral health including the number of decayed, missing, and filled teeth (DMFT) and periodontal indices in postmenopausal women with osteoporosis, osteoporosis treated with bisphosphonate therapy, and control group and to examine the correlation between dental panoramic indices (Mental Index—MI, Mandibular Cortical Index—MCI) and bone mineral density in these three groups of patients.

Materials and methods

The presented non-interventional study involved 120 postmenopausal women: women with osteoporosis (O) (n = 45), women with osteoporosis treated with bisphosphonates (OBP) (n = 45), and control group (C) (n = 30). DMFT, plaque, gingival and papilla bleeding index, pocket depth, clinical attachment loss, and the presence of periodontitis were evaluated for each patient. MI and MCI of all participants were measured on a dental panoramic radiograph.

Results

Group OBP showed significantly higher gingival, bleeding index and deeper pocket depth than C and/or O group. No significant differences were found in MI (p = .303) or MCI (p = .06) in all the examined groups. Also, there were no significant differences between the three groups in the presence of periodontitis as well as in the DMFT index.

Conclusion

BP therapy could have a negative influence on periodontal health. Further, MI and MCI are not precise diagnostic tools for diagnosing low BMD in postmenopausal women.

Clinical relevance

BP therapy could have a negative influence on the determinants of oral health in postmenopausal women with osteoporosis.

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Authors and Affiliations

  1. Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia

    Olja Grgić, Tanja Veljović & Tatjana Maravić

  2. Clinic of Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Vojvodina; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia

    Branka Kovačev-Zavišić & Jovanka Novaković-Paro

  3. Department of Oral Surgery, Dental Clinic of Vojvodina, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 12, Novi Sad, 21000, Serbia

    Branislav Bajkin

Authors
  1. Olja Grgić
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  2. Branka Kovačev-Zavišić
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  3. Tanja Veljović
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  4. Jovanka Novaković-Paro
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  5. Tatjana Maravić
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Correspondence to Branislav Bajkin.

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Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

Conflict of interest

The authors declare that they have no conflict of interest.

Funding

This research received support from the Ministry of Education, Science and Technological Development of the Republic of Serbia (grants No. TR31011 and III45016).

Informed consent

Informed consent was obtained from all participants of the study.

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Grgić, O., Kovačev-Zavišić, B., Veljović, T. et al. The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women. Clin Oral Invest 21, 151–157 (2017). https://doi.org/10.1007/s00784-016-1767-6

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  • DOI: https://doi.org/10.1007/s00784-016-1767-6

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