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The association between temporomandibular disorders and joint hypermobility syndrome: a nationwide population-based study

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Abstract

Objectives

This study aims to investigate the risk factors of temporomandibular disorders (TMDs), including disc or non-disc-related disorders, and joint hypermobility syndrome (JHS) retrospectively and to analyze the factors by estimating the magnitude of the association between the two conditions using a nationwide population-based dataset.

Materials and methods

A total of 975,788 eligible patients’ de-identified data were obtained from a representative database composed of one million of Taiwan’s population since 2004 to 2008. All associated factors, such as gender, age, facial trauma, and psychosis, which correlated with TMDs and JHS were examined. Multiple logistic regression modeling adjusted for confounding variables to determine the odds ratio of variables that made an important contribution to TMDs and JHS.

Results

For all TMDs patients, only 1.47 % patients had disc-related disorders. For all JHS patients, only 3.85 % patients are diagnosed with concomitant TMDs. Statistically significant association was observed between joint hypermobility and TMDs. Furthermore, the prevalence of JHS patients shows significant difference within TMD subgroups, in which 9.52 % of JHS patients have disc disorders and 90.48 % of JHS patients do not. All associated factors, such as gender, age, JHS, facial trauma, and psychosis, had a significant impact on the TMDs. Interestingly, patients with TMJ articular disc disorders are 6.7 times more likely to be diagnosed with JHS compared to patients without disc-related disorders.

Conclusions

Our results confirm that there is a significant positive association between TMDs and JHS, highlighting that patients with disc-related TMDs are more likely to experience JHS than patients with TMDs without disc disorders.

Clinical relevance

Individuals with TMD associated with JHS should be carefully evaluated by inter-disciplinary specialists as these factors may eventually have impact on the prognosis of TMDs and JHS.

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Acknowledgments

This study was partly supported by Tri-Service General Hospital, National Defense Medical Center (TSGH-C103-038). The authors acknowledge Ms. Cathy Tsai (School of Dentistry, N.D.M.C) for her help in manuscript and English editing.

Conflict of interest

The authors declare no conflicts of interest related to this study. This study is based in part on data from the National Health Insurance Research Database (NHIRD-103-029) provided by the National Health Insurance Administration, Ministry of Health and Welfare, Taiwan, and managed by the National Health Research Institutes. The interpretations and conclusions contained herein do not represent those of the National Health Insurance Administration, Ministry of Health and Welfare, or the National Health Research Institutes.

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Authors and Affiliations

  1. Department of Dentistry, Taiwan Adventist Hospital, Taipei, Taiwan

    Ting-Han Chang

  2. Department of Oral and Maxillofacial Surgery, School of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan

    Ting-Han Chang

  3. Department of Periodontology, School of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan

    Da-Yo Yuh, Wan-Chien Cheng, Earl Fu & Ren-Yeong Huang

  4. Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan

    Yung-Tsan Wu

  5. School of Public Health, National Defense Medical Center, Taipei, Taiwan

    Fu-Gong Lin

  6. Department of Oral Diagnosis and Pathology, School of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan

    Yi-Shing Shieh

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  1. Ting-Han Chang
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Correspondence to Ren-Yeong Huang.

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Chang, TH., Yuh, DY., Wu, YT. et al. The association between temporomandibular disorders and joint hypermobility syndrome: a nationwide population-based study. Clin Oral Invest 19, 2123–2132 (2015). https://doi.org/10.1007/s00784-015-1422-7

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  • DOI: https://doi.org/10.1007/s00784-015-1422-7

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