Skip to main content

Advertisement

Log in

Oral health in perimenopausal and early postmenopausal women from baseline to 2 years of follow-up with reference to hormone replacement therapy

  • Original Article
  • Published:
Clinical Oral Investigations Aims and scope Submit manuscript

Abstract

Female sex hormones also affect the mouth but there are little data on oral health of menopause age women. This 2-year follow-up study investigated oral health of perimenopausal and early postmenopausal women. Because hormone replacement therapy (HRT) users have been reported to be more health conscious than nonusers, we expected differences between women using and women not using HRT. Of 3,173 women, a random sample of 400 (200 using and 200 not using HRT) was examined. Of them, 161 case–control pairs of women using/not using HRT were reexamined 2 years later. Dental and periodontal status was recorded according to the WHO criteria and resting and stimulated saliva flow was measured. Panoramic tomography of the jaws was taken at baseline and at follow-up. The patients also filled in a structured questionnaire on their systemic health, medication, and health habits. The results were analyzed statistically between and within the groups. No difference was observed in any dental parameters or salivary flow rates between the groups. However, during the follow-up, women in HRT group had received more dental restorations (p < 0.05) and they also reported more often recent dental appointments (p < 0.05). Although no difference in oral health status or salivary flow rates between women using or not using HRT was found, the observation on dental restorations may indicate a more health conscious attitude in the HRT group.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Ahlberg J, Tuominen R, Murtomaa H (1996) Periodontal status among male industrial workers in southern Finland with or without access to subsidized dental care. Acta Odontol Scand 54:166–170

    Article  PubMed  Google Scholar 

  2. Ainamo J, Barmes D, Beagrie G, Cutress T, Martin J, Sardo-Infirri J (1982) Development of the World Health Oranization (WHO) Community Periodontal Index of Treatment Need (CPITN). Int Dent J 32:281–291

    PubMed  Google Scholar 

  3. Ajwani S, Tervonen T, Närhi T, Ainamo A (2001) Periodontal health status and treatment needs among elderly. Spec Care Dentist 21:98–103

    Article  PubMed  Google Scholar 

  4. Arafat AH (1974) Periodontal status during pregnancy. J Periodontol 45:641–643

    PubMed  Google Scholar 

  5. Bergdahl M (2000) Salivary flow and oral complaints in adult dental patients. Community Dent Oral Epidemiol 28:59–66

    Article  PubMed  Google Scholar 

  6. Brace M, McCauley E (1997) Oestrogens and psychological well-being. Ann Med 29:283–290

    Article  PubMed  Google Scholar 

  7. Cherry N, Gilmour K, Hannaford P, Heagerty A, Khan MA, Kitchener H, McNamee R, Elstein M, Kay C, Seif M, Buckley H (2002) Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial. Lancet 360:2001–2008

    Article  PubMed  Google Scholar 

  8. Cutress TW, Ainamo J, Sardo-Infirri J (1987) The Community Periodontal Index of Treatment Needs (CPITN) procedure for population groups and individuals. Int Dent J 37:222–233

    PubMed  Google Scholar 

  9. Dural S, Cağirankaya LB (2007) Does menstrual cycle effect buffer capacity of stimulated saliva? Clin Oral Investig 11:207–209

    Article  PubMed  Google Scholar 

  10. Evio S, Tarkkila L, Sorsa T, Furuholm J, Valimaki M, Ylikorkala O, Tiitinen A, Meurman J (2006) Effects of alendronate and hormone replacement therapy, alone and in combination, on saliva, periodontal conditions and gingival crevicular fluid matrix metalloproteinase-8 levels in women with osteoporosis. Oral Dis 12:187–193

    Article  PubMed  Google Scholar 

  11. Friedlander AH (2002) The physiology, medical management and oral implications of menopause. J Am Dent Assoc 133:73–81

    PubMed  Google Scholar 

  12. Frutos R, Rodriguez S, Miralles-Jorda L, Machuca G (2002) Oral manifestations and dental treatment in menopause. Med Oral 7:26–35

    PubMed  Google Scholar 

  13. Fure S, Zickert I (1997) Incidence of tooth loss and dental caries in 60-, 70-, and 80-year-old Swedish individuals. Community Dent Oral Epidemiol 25:137–142

    Article  PubMed  Google Scholar 

  14. Grodstein F, Colditz GA, Stampfer MJ (1998) Tooth loss and hormone use in postmenopausal women. Compend Contin Educ Dent 22:S9–S16

    Google Scholar 

  15. Grodstein F, Stampfer R (1995) The epidemiology of coronary heart disease and estrogen replacement in postmenopausal women. Prog Cardiovasc Dis 38:199–121

    Article  Google Scholar 

  16. Hemminki E, Malin M, Topo P (1993) Selection to postmenopausal therapy by women’s characteristics. J Clin Epidemiol 46:211–219

    Article  PubMed  Google Scholar 

  17. Herrington DM, Reboussin DM, Brosnihan KB, Sharp PC, Shumaker SA, Snyder TE, Furberg CD, Kowalchuk GJ, Stuckey TD, Rogers WJ, Givens DH, Waters D (2000) Effects of estrogen replacement on the progression of coronary-artery atherosclerosis. N Engl J Med 343:522–529

    Article  PubMed  Google Scholar 

  18. Hildebrandt CG, Loesche WJ, Lin CF, Bretz WA (1995) Comparison of the number and type of dental functional units in geriatric populations with diverse medical backgrounds. J Prosthet Dent 73:253–261

    Article  PubMed  Google Scholar 

  19. Janket SJ, Baird A, Chuang S, Jones JA (2003) Meta-analysis of periodontal disease and risk of coronary heart disease and stroke. Oral Surg Oral Med Oral Pathol Oral Radiol Endo 95:559–569

    Article  Google Scholar 

  20. Klock B, Svanberg M, Petersson LG (1990) Dental caries, mutans streptococci, lactobacilli, and saliva secretion rate in adults. Community Dent Oral Epidemiol 18:249–252

    Article  PubMed  Google Scholar 

  21. Laine M (2002) Effect of pregnancy on periodontal and dental health (review). Acta Odontol Scand 60:257–264

    Article  PubMed  Google Scholar 

  22. Löe H, Silness J (1963) Periodontal disease in pregnancy. Prevalence and severity. Acta Odontol Scand 21:533–551

    Article  PubMed  Google Scholar 

  23. Loesche WJ, Schork A, Terpenning MS, Chen Y-M, Stoll J (1995) Factors which influence levels of selected organism in saliva of older individuals. J Clin Microbiol 33:2550–2557

    PubMed  Google Scholar 

  24. Mariotti A (1994) Sex steroid hormones and cell dynamics in the periodontium. Critic Rev Oral Biol Med 5:27–53

    Google Scholar 

  25. Matthews KA (1992) Myths and realities of the menopause. Psychosom Med 54:1–9

    PubMed  Google Scholar 

  26. Matthews KA, Kuller LH, Wing RR, Meilahn EN, Plantinga P (1996) Prior to use estrogen replacement therapy, are users healthier than nonusers? Am J Epidemiol 143:971–978

    PubMed  Google Scholar 

  27. Meurman JH, Rantonen P (1994) Salivary flow rate, buffering capacity, and yeast counts in 187 consecutive adult patients from Kuopio, Finland. Scand J Dent Res 102:229–234

    PubMed  Google Scholar 

  28. Meurman JH, Furuholm J, Kaaja R, Rintamäki H (2006) Oral health in women with pregnancy and delivery complications. Clin Oral Invest 10:96–101

    Article  Google Scholar 

  29. Ogawa H, Yoshihara A, Hirotomi T, Ando Y, Miyazaki H (2002) Risk factors for periodontal disease progression among elderly people. J Clin Periodontol 29:592–597

    Article  PubMed  Google Scholar 

  30. Pajukoski H, Meurman JH, Snellman-Gröhn S, Sulkava R (1999) Oral health in hospitalized and nonhospitalized community dwelling elderly patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endo 88:437–443

    Article  Google Scholar 

  31. Pilgram TK, Hildebolt CF, Dotson M, Cohen SC, Hauser JF, Kardaris E, Civitelli R (2002) Relationships between clinical attachment level and spine and hip bone mineral density: data from healthy postmenopausal women. J Periodontol. 73:298–301

    Article  PubMed  Google Scholar 

  32. Powell LV, Leroux BG, Persson RE, Kiyak HA (1998) Factors associated with caries incidence in an elderly population. Community Dent Oral Epidemiol 26:170–176

    Article  PubMed  Google Scholar 

  33. Reinhard RA, Payne JB, Maze CA, Patil KD, Gallagher SJ, Mattson JS (1999) Influence of estrogen and osteopenia/osteoporosis on clinical periodontitis in postmenopausal women. J Periodontol 70:823–828

    Article  Google Scholar 

  34. Schuller AA, Holst D (1998) Changes in the oral health of adults from Trondelag, Norway, 1973–1983–1994. Community Dent Oral Epidemiol 26:201–208

    Article  PubMed  Google Scholar 

  35. Seeman E, Tsalamandris C, Bass S, Pearce G (1995) Present and future osteoporosis therapy. Bone 17:235–295

    Article  Google Scholar 

  36. Söder P-Ö, Jin LJ, Söder B, Wikner S (1994) Periodontal status in an urban adult population in Sweden. Community Dent Oral Epidemiol 22:106–111

    Article  PubMed  Google Scholar 

  37. Soory M (2000) Targets for steroid hormone mediated actions of periodontal pathogens, cytokines and therapeutic agents: some implications on tissue turnover in the periodontium. Curr Drug Targets 1:309–325

    Article  PubMed  Google Scholar 

  38. Tarkkila L, Linna M, Tiitinen A, Lindqvist C, Meurman JH (2001) Oral symptoms at menopause—the role of hormone replacement therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endo 92:276–280

    Article  Google Scholar 

  39. Tonnetti MS (1998) Cigarette smoking and periodontal diseases: etiology and management of disease. Ann Periodontol 3:88–101

    Google Scholar 

  40. Topo P, Klaukka T, Hemminki E, Uutela A (1991) Use of hormone replacement therapy in 1976–1989 by 45–64 year old Finnish women. J Epidemiol Community Health 45:277–280

    PubMed  Google Scholar 

  41. Topo P, Luoto R, Hemminki E, Uutela A (1999) Declining socioeconomic differences in the use of menopausal and postmenopausal hormone therapy in Finland. Maturitas 32:141–145

    Article  PubMed  Google Scholar 

  42. Unell L, Söderfeldt B, Halling A, Birkhed D (2000) Explanatory models for clinical and subjective indicators of periodontal disease in an adult population. J Clin Periodontol 27:22–29

    Article  PubMed  Google Scholar 

  43. World Health Organization (1997) Oral health surveys, 5thth edn. WHO, Geneva

    Google Scholar 

  44. Writing Group for the Women’s Health Initiative Investigators (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women’s Health Initiative randomized controlled trial. J Am Med Assoc 288:321–333

    Article  Google Scholar 

  45. Yalcin F, Gurgan S, Gurgan T (2005) The effect of menopause, hormone replacement therapy (HRT), alendronate (ALN), and calcium supplements on saliva. J Contemp Dent Pract 6:10–17

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. Tarkkila.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tarkkila, L., Furuholm, J., Tiitinen, A. et al. Oral health in perimenopausal and early postmenopausal women from baseline to 2 years of follow-up with reference to hormone replacement therapy. Clin Oral Invest 12, 271–277 (2008). https://doi.org/10.1007/s00784-008-0190-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00784-008-0190-z

Keywords

Navigation