Skip to main content

Advertisement

Log in

Metal content of biopsies adjacent to dental cast alloys

  • Original Article
  • Published:
Clinical Oral Investigations Aims and scope Submit manuscript

Abstract

Single case reports indicate that components of dental alloys accumulate in the adjacent soft tissue of the oral cavity. However, data on a wider range of dental alloys and patient groups are scarce. Therefore, the aim of the present study was to examine the metal content of oral tissues adjacent to dental alloys showing persisting signs of inflammation or other discoloration (affected sites) and of healthy control sites with no adjacent metal restoration in 28 patients. The composition of the adjacent alloys was analyzed and compared to the alloy components in the affected sites. Tissue analysis was performed using atomic absorption spectroscopy. Alloy analysis was performed with energy-dispersive X-ray analysis. In the affected sites, the metals Ag, Au, Cu, and Pd prevailed compared to control sites, reflecting the frequency distribution of single metals in the adjacent alloys. In most cases (84%), at least one of the analyzed metals was a component of the alloy and also detected in the tissue. Metal components from almost all dental cast alloys can be detected in adjacent tissue.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.

Similar content being viewed by others

References

  1. Bergenholtz A, Hedegård B, Söremark R (1965) Studies of the transport of metal ions from gold inlays into environmental tissues. Acta Odont Scand 23:135–146

    CAS  Google Scholar 

  2. Bundesärztekammer (Bundesverband der deutschen Zahnärztekammern) und Kassenzahnärztliche Bundesvereinigung (1995) Das Dental Vademekum. Deutscher Ärzte-Verlag, Köln München

  3. Cherian M, Goyer R (1978) Metallothioneins and their role in the metabolism and toxicity of metals. Life Sci 23:1–9

    Article  PubMed  Google Scholar 

  4. Datenbank für Dentale Metallegierungen (1997) Von Praktikern für Praktiker; für (fast) alle Legierungen, die Zahnärzte in Deutschland einsetzen können. Edn 1.0. Spitta, Balingen

  5. European Committee for Standardization (1995) EN ISO 1562: dental casting alloys. Brussels

    Google Scholar 

  6. European Committee for Standardization (1996) EN ISO 6871–1: dental base metal casting alloys. Part 1: cobalt-based alloys. Brussels

    Google Scholar 

  7. European Committee for Standardization (2000) EN ISO 8891: Dental casting alloys with noble metal content of at least 25% but less than 75%. Brussels

    Google Scholar 

  8. Garhammer P, Schmalz G, Hiller KA, Reitinger T (2001) Patients with local adverse effects from dental cast alloys: frequency, complaints, symptoms, allergy. Clin Oral Invest 5:240–249

    Article  Google Scholar 

  9. Geurtsen W (2002) Biocompatibility of dental casting alloys. Crit Rev Oral Biol Med 13:71–84

    PubMed  Google Scholar 

  10. Gray SJ, Stirling K (1950) Tagging of red cells and plasma proteins with radioactive chromium. J Clin Invest 29:1604–1613

    Google Scholar 

  11. Hensten-Pettersen A (1992) Casting alloys: side effects. Adv Dent Res 6:38–43

    PubMed  Google Scholar 

  12. Kratzenstein B, Sauer KH, Weber H, Geis-Gerstofer J (1986) In-vivo-Korrosionsuntersuchungen goldhaltiger Legierungen. Dtsch Zahnärztl Z 41:1272–1276

  13. Lau JC, Jackson-Boeters L, Daley TD, Wysocki GP, Cherian MG (2001) Metallothionein in human gingival amalgam tattoos. Arch Oral Biol 46:1015–1020

    Article  PubMed  Google Scholar 

  14. Marcusson JA (1996) Contact allergies to nickel sulfate, gold sodium thiosulfate and palladium chloride in patients claiming side effects from dental alloy components. Contact Dermatitis 34:320–323

    PubMed  Google Scholar 

  15. Nau H (1997) Toxikokinetik. In: Marquard H, Schäfer SG (eds) Lehrbuch der Toxikologie. Spektrum, Heidelberg

  16. Rechmann P (1992) LAMMS and ICP-MS detection of dental metallic compounds in not-discolored human gingiva. J Dent Res 71:599

    Google Scholar 

  17. Rechmann P (1993) Nachweis metallischer Restaurationsmaterialien in klinisch unauffälliger Gingiva. Dsch Zahnärztl Z 48:270–275

    Google Scholar 

  18. Rechmann P (1995) Aufnahme von Metallen in die Mundschleimhaut. Dtsch Z Mund Kiefer GesichtsChir 19:107–114

    Google Scholar 

  19. Reynolds JJ, Meikle MC (1997) Mechanisms of connective tissue matrix destruction in periodontitis. Periodontology 2000 14:144–157

    CAS  PubMed  Google Scholar 

  20. Schäfer SG, Hannover B, Elsenhaus B, Forth W, Schümann K (1997) Metalle. In: Marquard H, Schäfer SG: Lehrbuch der Toxikologie. Spektrum, Heidelberg

  21. Schmalz G, Garhammer P (2002) Biologic interactions of dental cast alloys with oral tissues. Dent Mat 18:396–406

    Article  CAS  Google Scholar 

  22. Taylor DT, Morton TH Jr (1991) Ulcerative lesions of the palate associated with removable partial denture castings. J Prosthet Dent 66:213–221

    CAS  PubMed  Google Scholar 

  23. Wataha JC (2000) Biocompatibility of dental casting alloys: A review. J Prosthet Dent 83:223–234

    CAS  PubMed  Google Scholar 

  24. Wirz J, Schmidli F (1988) Korrosionsverhalten von Co-Basislegierungen für Kronen- und Brückenarbeiten. Quintessenz 11:1997–2008

    Google Scholar 

  25. Wirz J, Schmidli F, Jäger K (1992) Splittertest. Quintessenz 43:1017–1023

    Google Scholar 

Download references

Acknowledgements

This study was supported by the German Ministry of Health. We thank Peter Geisenberger for EDX analysis of the cast alloys.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Pauline Garhammer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Garhammer, P., Schmalz, G., Hiller, KA. et al. Metal content of biopsies adjacent to dental cast alloys. Clin Oral Invest 7, 92–97 (2003). https://doi.org/10.1007/s00784-003-0204-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00784-003-0204-9

Keywords

Navigation