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Effects of additional resistance training during diet-induced weight loss on bone mineral density in overweight premenopausal women

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Abstract

Bone loss accompanies a diet-induced weight loss and could be prevented with a combination of exercises. This study was conducted to examine the effects of additional resistance training during diet-induced weight loss on whole-body and selected regional bone mineral density (BMD). The participants of a 14-week weight-loss study were 42 overweight premenopausal Japanese women who were randomly placed in either a diet-only group (D; n = 21) or a diet plus resistance training group (DR; n = 21). Whole-body BMD and body composition, lumbar spine BMD, and 1/3 radial BMD were measured by dual-energy X-ray absorptiometry before and after the intervention. Bone formation and resorption markers were also measured. Thirty-five participants (83%) completed the study. Individuals in groups D (n = 17) and DR (n = 18) lost 6.2 ± 3.5 kg and 8.6 ± 3.6 kg body weight, respectively. Reductions in percentage fat mass and fat mass in group DR were significantly greater than in group D; lean mass decreased significantly in both groups. The effect of time on whole-body BMD was significant (−0.3%); however, whole-body bone mineral content, lumbar spine BMD, and 1/3 radial BMD remained unchanged. There were no significant timeby-group interactions in the whole-body and regional BMD and bone markers. These results suggest that additional resistance training during weight loss has no effect on BMD in overweight premenopausal Japanese women. Further long-term studies with large numbers of subjects are needed.

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References

  1. Kenchaiah S, Evans JC, Levy D, Wilson PW, Benjamin EJ, Larson MG, Kannel WB, Vasan RS (2002) Obesity and the risk of heart failure. N Engl J Med 347:305–313

    Article  PubMed  Google Scholar 

  2. Rexrode KM, Hennekens CH, Willett WC, Colditz GA, Stampfer MJ, Rich-Edwards JW, Speizer FE, Manson JE (1997) A prospective study of body mass index, weight change, and risk of stroke in women. JAMA 277:1539–1545

    Article  PubMed  CAS  Google Scholar 

  3. Mendez MA, Monteiro CA, Popkin BM (2005) Overweight exceeds underweight among women in most developing countries. Am J Clin Nutr 81:714–721

    PubMed  CAS  Google Scholar 

  4. Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, Marks JS (2003) Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 289:76–79

    Article  PubMed  Google Scholar 

  5. Rippe JM, McInnis KJ, Melanson KJ (2001) Physician involvement in the management of obesity as a primary medical condition. Obes Res 4:302S–311S

    Article  Google Scholar 

  6. Ensrud KE, Ewing SK, Stone KL, Cauley JA, Bowman PJ, Cummings SR; Study of Osteoporotic Fractures Research Group. (2003) Intentional and unintentional weight loss increase bone loss and hip fracture risk in older women. J Am Geriatr Soc 51:1740–1747

    Article  PubMed  Google Scholar 

  7. Knoke JD, Barrett-Connor E (2003) Weight loss: a determinant of hip bone loss in older men and women. The Rancho Bernardo Study. Am J Epidemiol 158:1132–1138

    Article  PubMed  Google Scholar 

  8. Macdonald HM, New SA, Campbell MK, Reid DM (2005) Influence of weight and weight change on bone loss in perimenopausal and early postmenopausal Scottish women. Osteoporos Int 16: 163–171

    Article  PubMed  Google Scholar 

  9. Nguyen TV, Sambrook PN, Eisman JA (1998) Bone loss, physical activity, and weight change in elderly women: the Dubbo Osteoporosis Epidemiology Study. J Bone Miner Res 13:1458–1467

    Article  PubMed  CAS  Google Scholar 

  10. Espallargues M, Sampietro-Colom L, Estrada MD, Sola M, del Rio L, Setoain J, Granados A (2001) Identifying bone-mass-related risk factors for fracture to guide bone densitometry measurements: a systematic review of the literature. Osteoporos Int 12:811–822

    Article  PubMed  CAS  Google Scholar 

  11. Chao D, Espeland MA, Farmer D, Register TC, Lenchik L, Applegate WB, Ettinger WH Jr (2000) Effect of voluntary weight loss on bone mineral density in older overweight women. J Am Geriatr Soc 48:753–759

    PubMed  CAS  Google Scholar 

  12. Compston JE, Laskey MA, Croucher PI, Coxon A, Kreitzman S (1992) Effect of diet-induced weight loss on total body bone mass. Clin Sci 82:429–432

    PubMed  CAS  Google Scholar 

  13. Jensen LB, Quaade F, Sorensen OH (1994) Bone loss accompanying voluntary weight loss in obese humans. J Bone Miner Res 9:459–463

    PubMed  CAS  Google Scholar 

  14. Jensen LB, Kollerup G, Quaade F, Sorensen OH (2001) Bone minerals changes in obese women during a moderate weight loss with and without calcium supplementation. J Bone Miner Res 16:141–147

    Article  PubMed  CAS  Google Scholar 

  15. Pritchard JE, Nowson CA, Wark JD (1996) Bone loss accompanying diet-induced or exercise-induced weight loss: a randomised controlled study. Int J Obes Relat Metab Disord 20:513–520

    PubMed  CAS  Google Scholar 

  16. Ramsdale SJ, Bassey EJ (1994) Changes in bone mineral density associated with dietary-induced loss of body mass in young women. Clin Sci 87:343–348

    PubMed  CAS  Google Scholar 

  17. Ricci TA, Heymsfield SB, Pierson RN Jr, Stahl T, Chowdhury HA, Shapses SA (2001) Moderate energy restriction increases bone resorption in obese postmenopausal women. Am J Clin Nutr 73:347–352

    PubMed  CAS  Google Scholar 

  18. Riedt CS, Cifuentes M, Stahl T, Chowdhury HA, Schlussel Y, Shapses SA (2005) Overweight postmenopausal women lose bone with moderate weight reduction and 1 g/day calcium intake. J Bone Miner Res 20:455–463

    Article  PubMed  CAS  Google Scholar 

  19. The Examination Committee of Criteria for “Obesity Disease” in Japan; Japan Society for the Study of Obesity (2002) New criteria for “obesity disease” in Japan. Circ J 66:987–992

    Article  Google Scholar 

  20. Nelson ME, Fiatarone MA, Morganti CM, Trice I, Greenberg RA, Evans WJ (1994) Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. A randomized controlled trial. JAMA 272:1909–1914

    Article  PubMed  CAS  Google Scholar 

  21. Wolff I, van Croonenborg JJ, Kemper HC, Kostense PJ, Twisk JW (1999) The effect of exercise training programs on bone mass: a meta-analysis of published controlled trials in pre-and postmenopausal women. Osteoporos Int 9:1–12

    Article  PubMed  CAS  Google Scholar 

  22. Kerr D, Morton A, Dick I, Prince R (1996) Exercise effects on bone mass in postmenopausal women are site-specific and load-dependent. J Bone Miner Res 11:218–225

    Article  PubMed  CAS  Google Scholar 

  23. Daly RM, Dunstan DW, Owen N, Jolley D, Shaw JE, Zimmet PZ (2005) Does high-intensity resistance training maintain bone mass during moderate weight loss in older overweight adults with type 2 diabetes? Osteoporos Int 16:1703–1712

    Article  PubMed  Google Scholar 

  24. Duplay D (2005) Physicians’ Desk Reference for Nonprescription Drugs and Dietary Supplements, 26th edn. Thomson PDR, Montvale, NJ

    Google Scholar 

  25. Fleck SJ, Kraemer WJ (1987) Designing Resistance Training Programs. Human Kinetics Books, Champaign, IL

    Google Scholar 

  26. Nakata Y, Tanaka K, Mizuki T, Yoshida T (2004) Body composition measurements by dual-energy X-ray absorptiometry differ between two analysis modes. J Clin Densitom 7:443–447

    Article  PubMed  Google Scholar 

  27. Crouter SE, Schneider PL, Karabulut M, Bassett DR Jr (2003) Validity of 10 electronic pedometers for measuring steps, distance, and energy cost. Med Sci Sports Exerc 35:1455–1460

    Article  PubMed  Google Scholar 

  28. Andersen RE, Wadden TA, Herzog RJ (1997) Changes in bone mineral content in obese dieting women. Metabolism 46:857–861

    Article  PubMed  CAS  Google Scholar 

  29. Shapses SA, Riedt CS (2006) Bone, body weight, and weight reduction: what are the concerns? J Nutr 136:1453–1456

    PubMed  CAS  Google Scholar 

  30. Skov AR, Haulrik N, Toubro S, Molgaard C, Astrup A (2002) Effect of protein intake on bone mineralization during weight loss: a 6-month trial. Obes Res 10:432–438

    PubMed  Google Scholar 

  31. Bowen J, Noakes M, Clifton PM (2004) A high dairy protein, high-calcium diet minimizes bone turnover in overweight adults during weight loss. J Nutr 134:568–573

    PubMed  CAS  Google Scholar 

  32. Ricci TA, Chowdhury HA, Heymsfield SB, Stahl T, Pierson RN Jr, Shapses SA (1998) Calcium supplementation suppresses bone turnover during weight reduction in postmenopausal women. J Bone Miner Res 13:1045–1050

    Article  PubMed  CAS  Google Scholar 

  33. Shapses SA, Von Thun NL, Heymsfield SB, Ricci TA, Ospina M, Pierson RN Jr, Stahl T (2001) Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation. J Bone Miner Res 16:1329–1336

    Article  PubMed  CAS  Google Scholar 

  34. Madsen OR, Jensen JE, Sorensen OH (1997) Validation of a dual energy X-ray absorptiometer: measurement of bone mass and soft tissue composition. Eur J Appl Physiol Occup Physiol 75:554–558

    Article  PubMed  CAS  Google Scholar 

  35. Svendsen OL, Haarbo J, Hassager C, Christiansen C (1993) Accuracy of measurements of body composition by dual-energy x-ray absorptiometry in vivo. Am J Clin Nutr 57:605–608

    PubMed  CAS  Google Scholar 

  36. Svendsen OL, Hendel HW, Gotfredsen A, Pedersen BH, Andersen T (2002) Are soft tissue composition of bone and non-bone pixels in spinal bone mineral measurements by DXA similar? Impact of weight loss. Clin Physiol Funct Imaging 22:72–77

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Health and Sport Sciences, Center for Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, 305-8577, Japan

    Yoshio Nakata, Dong Jun Lee, Tomohiro Okura & Kiyoji Tanaka

  2. Health Promotion and Exercise Program, The National Institute of Health and Nutrition, Tokyo, Japan

    Kazunori Ohkawara

  3. Division of Physical Education Sport and Leisure Studies, Myongji University, Yongin, Korea

    Dong Jun Lee

  4. Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan

    Tomohiro Okura & Kiyoji Tanaka

Authors
  1. Yoshio Nakata
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  2. Kazunori Ohkawara
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  3. Dong Jun Lee
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  4. Tomohiro Okura
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  5. Kiyoji Tanaka
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Correspondence to Yoshio Nakata.

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Nakata, Y., Ohkawara, K., Lee, D.J. et al. Effects of additional resistance training during diet-induced weight loss on bone mineral density in overweight premenopausal women. J Bone Miner Metab 26, 172–177 (2008). https://doi.org/10.1007/s00774-007-0805-5

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  • DOI: https://doi.org/10.1007/s00774-007-0805-5

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