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The experience of depression, anxiety, and mania among perinatal women

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Abstract

We assessed differential item functioning (DIF) based on computerized adaptive testing (CAT) to examine how perinatal mood disorders differ from adult psychiatric disorders. The CAT-Mental Health (CAT-MH) was administered to 1614 adult psychiatric outpatients and 419 perinatal women with IRB approval. We examined individual item-level differences using logistic regression and overall score differences by scoring the perinatal data using the original bifactor model calibration based on the psychiatric sample data and a new bifactor model calibration based on the perinatal data and computing their correlation. To examine convergent validity, we computed correlations of the CAT-MH with contemporaneously administered Edinburgh Postnatal Depression Scales (EPDS). The rate of major depression in the perinatal sample was 13 %. Rates of anxiety, mania, and suicide risk were 5, 6, and 0.4 %, respectively. One of 66 depression items, one of 69 anxiety items, and 15 of 53 mania items exhibited DIF (i.e., failure to discriminate between high and low levels of the disorder) in the perinatal sample based on the psychiatric sample calibration. Removal of these items resulted in correlations of the original and perinatal calibrations of r = 0.983 for depression, r = 0.986 for anxiety, and r = 0.932 for mania. The 91.3 % of cases were concordantly categorized as either “at-risk” or “low-risk” between the EPDS and the perinatal calibration of the CAT-MH. There was little evidence of DIF for depression and anxiety symptoms in perinatal women. This was not true for mania. Now calibrated for perinatal women, the CAT-MH can be evaluated for longitudinal symptom monitoring.

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Acknowledgments

We would like to acknowledge the contributions of Kerry Swenson, MD, PhD, Lydia Muhlbach, RN, Jane Karol, Vania Blancas, Catherine Sanders, and Deanna Hanks, MHSA, FACHE, in facilitating data collection. We would like to thank Dave Patterson and Monica Jercan from Discerning Systems Inc. for programming support on customizing the CAT-MH™ for this study and providing data for the analysis. We would like to thank Yehuda Cohen from Adaptive Testing Technologies for donation of the CAT-MH™ tests. This work was previously presented in part at the 2nd Biennial Perinatal Mental Health Meeting, Chicago, IL, November 2015, and at the Biennial Meeting of the North American Society for Psychosocial Obstetrics and Gynecology, New York, NY, April 2016.

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Correspondence to J. Jo Kim.

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Robert Gibbons is a founder of Adaptive Testing Technologies that now distributes the CAT-MH™. Jo Kim, Richard Silver, Rita Elue, Marci Adams, Laura La Porte, Li Cai, and Jong Bae Kim declare that they have no conflict of interest.

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This study was funded by Satter Foundation.

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Kim, J.J., Silver, R.K., Elue, R. et al. The experience of depression, anxiety, and mania among perinatal women. Arch Womens Ment Health 19, 883–890 (2016). https://doi.org/10.1007/s00737-016-0632-6

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  • DOI: https://doi.org/10.1007/s00737-016-0632-6

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