Abstract
Reconstruction of vascular net of small laboratory animals from magnetic resonance imaging magnetic resonance imaging (MRI) data is associated with some problems. First of all this is due to the physics of nuclear magnetic resonance nuclear magnetic resonance signal registration. Scanner is sensible to the blood flow propagating through the section and shows real situation about vessel presence only if it is perpendicular to the scanning plane. If the vessel is parallel to the scanning plane scanner does not shows vessel presence. This circumstance causes the fragmentation of reconstructed vascular net. Despite the fact that all vessels in brain must be connected reconstructed vascular net consists of several fragments. We propose new algorithm allowing for reconstruction fragmentation-free vascular net according to the data of MRI scanner. Our approach is based on multiple scanning, object under consideration is probed by several sets of parallel planes. Our method allows for elimination or significant reduction mentioned disadvantage. The algorithm is applied to real MRI data of small laboratory animals and shows good results.
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Acknowledgments
Work of A. E. Akulov, M. P. Moshkin, A. A. Savelov and A. A. Tulupov was completed thanks to the support of Russian Science Foundation (project #14-35-00020, all MRI experimentation studies using Bruker BioSpec 117/16 USR scanner) and experiments were carried out on unique scientific installation - Centre for Genetic Resources Laboratory Animals (RFMEFI61914X0005 and RFMEFI62114X0010). Work of A. A. Cherevko, A. P. Chupakhin, A. K. Khe was completed thanks to the support of Russian Foundation for Basic Research (project #14-01-00036, mathematical modelling). Work of S. V. Maltseva was completed thanks to the support of Russian Foundation for Basic Research (project #15-01-00745 A, mathematical modelling).
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The study was completed thanks to the support of Russian Science Foundation (project #14-35-00020, all MRI experimentation studies using Bruker BioSpec 117/16 USR scanner), Russian Foundation for Basic Research (projects #14-01-00036, #15-01-00745 A, mathematical modelling). Experiments were carried out on unique scientific installation - Centre for Genetic Resources Laboratory Animals (RFMEFI61914X0005 and RFMEFI62114X0010).
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Maltseva, S.V., Cherevko, A.A., Khe, A.K. et al. Reconstruction of Complex Vasculature by Varying the Slope of the Scan Plane in High-Field Magnetic Resonance Imaging. Appl Magn Reson 47, 23–39 (2016). https://doi.org/10.1007/s00723-015-0726-8
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DOI: https://doi.org/10.1007/s00723-015-0726-8