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Highly efficient and chemoselective method for the thioacetalization of aldehydes and transthioacetalization of acetals and acylals catalyzed by H2SO4-silica under solvent-free conditions

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Abstract

Chemoselective and efficient thioacetalization of a variety of aldehydes was achieved in excellent yields at room temperature using 1,2-ethanedithiol in the presence of catalytic amounts of H2SO4-silica. Thioacetals were also prepared by transthioacetalization of acylals and acetals under similar conditions.

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Acknowledgments

We are grateful to Damghan University (grant no. 88/Chem/80/139) for financial support.

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Authors and Affiliations

  1. School of Chemistry, Damghan University, 36715364, Damghan, Iran

    Seied Ali Pourmousavi & Shaghayegh Sadat Kazemi

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  1. Seied Ali Pourmousavi
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  2. Shaghayegh Sadat Kazemi
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Correspondence to Seied Ali Pourmousavi.

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Pourmousavi, S.A., Kazemi, S.S. Highly efficient and chemoselective method for the thioacetalization of aldehydes and transthioacetalization of acetals and acylals catalyzed by H2SO4-silica under solvent-free conditions. Monatsh Chem 143, 917–923 (2012). https://doi.org/10.1007/s00706-011-0664-6

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  • DOI: https://doi.org/10.1007/s00706-011-0664-6

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