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Aminoalkylation with Aldehydes Mediated by Solid Lithium Perchlorate

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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary.

The solid LiClO4-mediated one-pot reaction of aldehydes with secondary amines and C nucleophiles afforded the corresponding aminoalkylation products in high yields. Unlike the previous reported procedure, the aminoalkylation of aldehyde was achieved in the presence of only 0.5 equivalents of solid lithium perchlorate in dichloromethane as the solvent with good to high yields at room temperature.

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Authors and Affiliations

  1. Department of Chemistry, Sharif University of Technology, P.O. Box 11365-9516, Tehran, Iran

    Mohammad R. Saidi & Mohammad Nazari

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  1. Mohammad R. Saidi
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  2. Mohammad Nazari
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Correspondence to Mohammad R. Saidi.

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Saidi, M., Nazari, M. Aminoalkylation with Aldehydes Mediated by Solid Lithium Perchlorate. Monatshefte für Chemie 135, 309–312 (2004). https://doi.org/10.1007/s00706-003-0093-2

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  • DOI: https://doi.org/10.1007/s00706-003-0093-2

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