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Duck circovirus in northern Vietnam: genetic characterization and epidemiological analysis

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Abstract

In the present study, tissue samples collected from 130 ducks from clinically suspected commercial flocks and diseased birds in six provinces of northern Vietnam were tested for duck circovirus (DuCV) infection. The DuCV genome was detected in 56 out of 130 (43.08%) duck samples by PCR. Of 38 tested farms, 26 (68.42%) were positive for the DuCV genome. The rate of the DuCV genome detection in ducks at 3–4 weeks of age (54.17%) was significantly higher (p < 0.05) than that at <3 (32.43%) and >7 (33.33%) weeks of age and insignificantly higher than that at 5–7 weeks of age (43.33%) (p = 0.11). The genomes of six Vietnamese DuCV isolates were determined. They ranged in length from 1,988 to 1,995 nucleotides, and their nucleotide sequences were 83.24% to 99.69% identical to each other. Phylogenetic analysis based on the complete genome sequences indicated that the DuCV strains circulating in northern Vietnam can be divided into two main genotypes (I and II) and several subgenotypes. The Vietnamese DuCV isolates were closely related to Chinese, Taiwanese, and Korean strains. One positively selected site was detected in the capsid protein.

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Acknowledgments

We thank Dr. Harold Browing (animal welfare advisor) at the Animal Welfare Foundation for English edits and proofreading of our manuscript.

Funding

This study was supported by the Vietnam-Belgium Project, AI Program with Vietnam National University of Agriculture (Grant No. T2021-08-14/VB).

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Authors and Affiliations

  1. Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Trau Quy Town, Gia Lam District, Hanoi, 131000, Vietnam

    Giang Thi Huong Tran, Ngan Thi Mai, Tra Thi Thu Vu, Van Phan Le & Hieu Van Dong

  2. National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi, Vietnam

    Vuong Nghia Bui & Tung Duy Dao

  3. Central Veterinary Medicine JSC No. 5, Ha Binh Phuong Industrial Zone, Hanoi, Vietnam

    Dai Quang Trinh

Authors
  1. Giang Thi Huong Tran
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  2. Ngan Thi Mai
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  3. Vuong Nghia Bui
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  4. Tung Duy Dao
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  5. Dai Quang Trinh
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  6. Tra Thi Thu Vu
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  7. Van Phan Le
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  8. Hieu Van Dong
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Contributions

GTHT, VPL, and HVD designed the research. HDV, GTHT, VPL, VNB, DQT, and TDD performed the research. GTHT, NTM, TTTV, and HVD contributed to sample collection. GTHT and HVD wrote the manuscript. All of the authors read and approved the final manuscript.

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Correspondence to Hieu Van Dong.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Tran, G.T.H., Mai, N.T., Bui, V.N. et al. Duck circovirus in northern Vietnam: genetic characterization and epidemiological analysis. Arch Virol 167, 1871–1877 (2022). https://doi.org/10.1007/s00705-022-05501-y

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  • DOI: https://doi.org/10.1007/s00705-022-05501-y

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