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An insertion and deletion mutant of adenovirus in Muscovy ducks

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Abstract

Duck adenovirus 3 (DuAdV-3; strain HB) was isolated and sequenced. The genome of the Muscovy-duck-origin virus contains a 54-bp insertion in pVIII, a 3-bp deletion in the overlap region of 100K, 22K, and 33K, a 42-bp deletion at the junction of ORF64 and ORF67, and a 715-bp deletion in right noncoding region of the genome. Notably, HB has a strikingly shorter right inverted terminal repeat (ITR) of 50 bp, whereas all other DuAdV-3 isolates have a 721-bp ITR. These findings demonstrate that HB is an insertion and deletion mutant of DuAdV-3.

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References

  1. Cao JX, Krell PJ, Nagy E (1998) Sequence and transcriptional analysis of terminal regions of the fowl adenovirus type 8 genome. J Gen Virol 79:2507–2516. https://doi.org/10.1099/0022-1317-79-10-2507

    Article  CAS  PubMed  Google Scholar 

  2. Cao Z, Zhang C, Liu Y, Liu Y, Ye W, Han J, Ma G, Zhang D, Xu F, Gao X, Tang Y, Shi S, Wan C, Zhang C, He B, Yang M, Lu X, Huang Y, Diao Y, Ma X, Zhang D (2011) Tembusu virus in ducks, China. Emerg Infect Dis 17:1873–1875. https://doi.org/10.3201/eid1710.101890

    Article  PubMed  PubMed Central  Google Scholar 

  3. Chang PC, Shien JH, Wang MS, Shieh HK (2000) Phylogenetic analysis of parvoviruses isolated in Taiwan from ducks and geese. Avian Pathol 29:45–49. https://doi.org/10.1080/03079450094270

    Article  CAS  PubMed  Google Scholar 

  4. Fu G, Cheng L, Shi S, Peng C, Chen H, Huang Y (2008) Genome cloning and sequence analysis of duck circovirus. Chin J Virol 24:138–143 ((in Chinese))

    CAS  Google Scholar 

  5. Fu Y, Pan M, Wang X, Xu Y, Yang H, Zhang D (2008) Molecular detection and typing of duck hepatitis A virus directly from clinical specimens. Vet Microbiol 131:247–257. https://doi.org/10.1016/j.vetmic.2008.03.011

    Article  CAS  PubMed  Google Scholar 

  6. Harrach B, Benkö M, Both GW, Brown M, Davison AJ, Echavarría M, Hess M, Jones MS, Kajon A, Lehmkuhl HD, Mautner V, Mittal SK, Wadell G (2011) Adenoviridae. In: King AMQ, Adams MJ, Carstens EB, Lefkowitz EJ (eds) Virus Taxonomy. Ninth Report of the International Committee on Taxonomy of Viruses. Elsevier Academic Press, San Diego, pp 125–141

    Google Scholar 

  7. Hatfield L, Hearing P (1991) Redundant elements in the adenovirus type 5 inverted terminal repeat promote bidirectional transcription in vitro and are important for virus growth in vivo. Virology 184:265–276. https://doi.org/10.1016/0042-6822(91)90843-z

    Article  CAS  PubMed  Google Scholar 

  8. Hay RT (1985) The origin of adenovirus DNA replication: minimal DNA sequence requirement in vivo. EMBO J 4:421–426

    Article  CAS  Google Scholar 

  9. Hoeben RC, Uil TG (2013) Adenovirus DNA replication. Cold Spring Harb Perspect Biol 5:a013003. https://doi.org/10.1101/cshperspect.a013003

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Hu Q, Chen S, Lin F, Cheng X, Lin T, Jiang B, Chen S, Cheng Y, Li Y, Zhu X (2004) The identification of Muscovy duck reovirus. Chin J Virol 20:242–248 ((in Chinese))

    Google Scholar 

  11. Kyoto University Bioinformatics Center (1991) Multiple sequence alignment by CLUSTALW. http://www.genome.jp/tools/clustalw/. Accessed 17 Jan 2021

  12. Lee MS, Chang PC, Shien JH, Cheng MC, Shieh HK (2001) Identification and subtyping of avian influenza viruses by reverse transcription-PCR. J Virol Methods 97:13–22. https://doi.org/10.1016/S0166-0934(01)00301-9

    Article  CAS  PubMed  Google Scholar 

  13. Leegwater PA, van Driel W, van der Vliet PC (1985) Recognition site of nuclear factor I, a sequence-specific DNA-binding protein from HeLa cells that stimulates adenovirus DNA replication. EMBO J 4:1515–1521

    Article  CAS  Google Scholar 

  14. Liu H, Wang Z, Wu Y, Zheng D, Sun C, Bi D, Zuo Y, Xu T (2007) Molecular epidemiological analysis of Newcastle disease virus isolated in China in 2005. J Virol Methods 140:206–211. https://doi.org/10.1016/j.jviromet.2006.10.012

    Article  CAS  PubMed  Google Scholar 

  15. Marek A, Kaján GL, Kosiol C, Harrach B, Schlötterer C, Hess M (2014) Complete genome sequences of pigeon adenovirus 1 and duck adenovirus 2 extend the number of species within the genus Aviadenovirus. Virology 462–463:107–114. https://doi.org/10.1016/j.virol.2014.04.033

    Article  CAS  PubMed  Google Scholar 

  16. Nagata K, Guggenheimer RA, Hurwitz J (1983) Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA. Proc Natl Acad Sci USA 80:6177–6181. https://doi.org/10.1073/pnas.80.20.6177

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. National Center for Biotechnology Information (2013) Basic Local Alignment Search Tool. http://blast.ncbi.nlm.nih.gov/Blast.cgi. Accessed 14 Jan 2021

  18. National Center for Biotechnology Information (2013) Nucleotide. https://www.ncbi.nlm.nih.gov/nuccore/?term=duck+adenovirus. Accessed 27 Oct 2021

  19. Pruijn GJ, van Driel W, van der Vliet PC (1986) Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication. Nature 322:656–659. https://doi.org/10.1038/322656a0

    Article  CAS  PubMed  Google Scholar 

  20. Rademaker HJ, Fallaux FJ, Van den Wollenberg DJM, De Jong RN, Van der Vliet PC, Hoeben RC (2006) Relaxed template specificity in fowl adenovirus 1 DNA replication initiation. J Gen Virol 87:553–562. https://doi.org/10.1099/vir.0.81328-0

    Article  CAS  PubMed  Google Scholar 

  21. Rosenfeld PJ, O’Neill EA, Wides RJ, Kelly TJ (1987) Sequence-specific interactions between cellular DNA-binding proteins and the adenovirus origin of DNA replication. Mol Cell Biol 7:875–886. https://doi.org/10.1128/mcb.7.2.875-886.1987

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Sambrook J, Russell DW (2001) Molecular cloning: a laboratory manual, 3rd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor

    Google Scholar 

  23. Shi S, Liu R, Wan C, Cheng L, Chen Z, Fu G, Chen H, Fu Q, Huang Y (2019) Isolation and characterization of duck adenovirus 3 circulating in China. Arch Virol 164:847–851. https://doi.org/10.1007/s00705-018-4105-2

    Article  CAS  PubMed  Google Scholar 

  24. Shi X, Zhang X, Sun H, Wei C, Liu Y, Luo J, Wang X, Chen Z, Chen H (2022) Isolation and pathogenic characterization of duck adenovirus 3 mutant circulating in China. Poult Sci 101:101564. https://doi.org/10.1016/j.psj.2021.101564

    Article  CAS  PubMed  Google Scholar 

  25. Shinagawa M, Padmanabhan R (1980) Comparative sequence analysis of the inverted terminal repetitions from different adenoviruses. Proc Natl Acad Sci USA 77:3831–3835. https://doi.org/10.1073/pnas.77.7.3831

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Stillman BW, Topp WC, Engler JA (1982) Conserved sequences at the origin of adenovirus DNA replication. J Virol 44:530–537. https://doi.org/10.1128/JVI.44.2.530-537.1982

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Todd D, Smyth VJ, Ball NW, Donnelly BM, Wylie M, Knowles NJ, Adair BM (2009) Identification of chicken enterovirus-like viruses, duck hepatitis virus type 2 and duck hepatitis virus type 3 as astroviruses. Avian Pathol 38:21–30. https://doi.org/10.1080/03079450802632056

    Article  CAS  PubMed  Google Scholar 

  28. Wides RJ, Challberg MD, Rawlins DR, Kelly TJ (1987) Adenovirus origin of DNA replication: sequence requirements for replication in vitro. Mol Cell Biol 7:864–874. https://doi.org/10.1128/mcb.7.2.864-874.1987

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Zhang X, Zhong Y, Zhou Z, Liu Y, Zhang H, Chen F, Chen W, Xie Q (2016) Molecular characterization, phylogeny analysis and pathogenicity of a Muscovy duck adenovirus strain isolated in China in 2014. Virology 493:12–21. https://doi.org/10.1016/j.virol.2016.03.004

    Article  CAS  PubMed  Google Scholar 

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Funding

This study was funded by China Agriculture Research System of MOF and MARA.

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Authors and Affiliations

  1. Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian district, Beijing, 100193, People’s Republic of China

    Lili Chu, Jiaying Wang, Duo Peng, Xiaoyan Wang & Dabing Zhang

  2. Institute of Animal Husbandry and Veterinary Sciences, Wuhan Academy of Agricultural Sciences, Wuhan, 430208, Hubei, People’s Republic of China

    Shengqiang Ye & Yunguo Qian

Authors
  1. Lili Chu
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  2. Shengqiang Ye
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  3. Jiaying Wang
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  4. Duo Peng
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  5. Xiaoyan Wang
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  6. Yunguo Qian
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  7. Dabing Zhang
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Correspondence to Yunguo Qian or Dabing Zhang.

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Chu, L., Ye, S., Wang, J. et al. An insertion and deletion mutant of adenovirus in Muscovy ducks. Arch Virol 167, 1879–1883 (2022). https://doi.org/10.1007/s00705-022-05474-y

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