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Reston virus in domestic pigs in China

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Abstract

Historically, Reston virus (RESTV) has been found to be associated with outbreaks of disease only in nonhuman primates. Its spread to domestic pigs was reported for the first time in 2008. In this study, we report the discovery, molecular detection, and phylogenetic analysis of Reston virus (RESTV) in domestic pigs in China. A total of 137 spleen specimens from pigs that died after showing typical clinical signs of porcine reproductive and respiratory syndrome (PRRS), and for which infection with porcine reproductive and respiratory syndrome virus (PRRSV) was confirmed by RT-PCR, were collected from three farms in Shanghai from February to September 2011. Of these samples, 2.92 % (4/137) were found to be positive for RESTV. All of the positive piglets were under the age of 8 weeks and were co-infected with PRRSV. Sequences were found that shared 96.1 %-98.9 % sequence similarity with those of two RESTV variants that had been discovered previously in domestic pigs and cynomolgus macaques from the Philippines. We therefore conclude that RESTV was present in domestic pigs in Shanghai, China.

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Acknowledgement

This work was supported by a grant from the National Natural Science Foundation of China, nos. 30960284 and 31260616.

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Authors and Affiliations

  1. The College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, People’s Republic of China

    Yangyang Pan, Meng Wang & Qiaoying Zeng

  2. Jiangsu University, Jiangsu, People’s Republic of China

    Wen Zhang

  3. Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai JiaoTong University, Shanghai, People’s Republic of China

    Li Cui & Xiuguo Hua

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  1. Yangyang Pan
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  2. Wen Zhang
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  3. Li Cui
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  4. Xiuguo Hua
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  5. Meng Wang
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  6. Qiaoying Zeng
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Corresponding author

Correspondence to Qiaoying Zeng.

Additional information

Y. Pan and Q. Zeng contributed equally to this article.

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Pan, Y., Zhang, W., Cui, L. et al. Reston virus in domestic pigs in China. Arch Virol 159, 1129–1132 (2014). https://doi.org/10.1007/s00705-012-1477-6

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  • DOI: https://doi.org/10.1007/s00705-012-1477-6

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