Abstract
The nature of SRV-4 infection in cynomolgus macaques remains unclear to date. Here, we report the monitoring of 24 cynomolgus monkeys that were naturally infected with SRV-4 for virus isolation, proviral load and antibody. The results indicated that the SRV-4 antibody status was statistically correlated to environmental temperature.
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Acknowledgments
We thank Cecilia Po for her assistance in preparation of this manuscript. We also thank JoAnn Yee and Nicholas Lerche (University of California, Davis) for kindly providing anti-SRV-1 sera for use in WB. We are grateful to Michele Carreon, Susan Gauntt, Sylvia Gonzalez-Arroyo, and Tiffany Rodriguez for SRV PCR and antibody screening. The authors also would like to acknowledge Lorna Millen for collecting samples and medical records, and Amando Elizondo and Daniel Buentello for collecting samples from SRV-4-infected animals.
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The opinions or assertions herein are the private views of the authors and are not to be constructed as reflecting the views of the Department of the Army or the Department of Defense. This work was funded by VRL Laboratories and Covance Research Products.
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Zao, CL., Ward, J.A., Tomanek, L. et al. Virological and serological characterization of SRV-4 infection in cynomolgus macaques. Arch Virol 156, 2053–2056 (2011). https://doi.org/10.1007/s00705-011-1068-y
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DOI: https://doi.org/10.1007/s00705-011-1068-y