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The complete genome sequences for three simian enteroviruses isolated from captive primates

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Abstract

In a recent study, we used RT-PCR and partial genome sequencing to detect simian enteroviruses SV6, SV19 and SV46, as well as two new enterovirus types (EV92 and EV103) in fecal specimens from rhesus macaques (Macaca mulatta), pigtail macaques (M. nemestrina), and sooty mangabeys (Cercocebus atys) with diarrheal disease at a US primate center. The complete genome sequences of representative SV46, EV92, and EV103 strains, presented here, show that SV46 and EV92 are typical of the simian enteroviruses classified within the species Human enterovirus A, while EV103 appears to belong to an unclassified species that also contains SV6 and N125/N203.

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References

  1. Jones DT, Taylor WR, Thornton JM (1992) The rapid generation of mutation data matrices from protein sequences. Comp Appl Biosci 8:275–282

    PubMed  CAS  Google Scholar 

  2. Junttila N, Leveque N, Kabue JP, Cartet G, Mushiya F, Muyembe-Tamfum JJ, Trompette A, Lina B, Magnius LO, Chomel JJ, Norder H (2007) New enteroviruses, EV-93 and EV-94, associated with acute flaccid paralysis in the Democratic Republic of the Congo. J Med Virol 79:393–400

    Article  PubMed  Google Scholar 

  3. Kalter SS (1982) Enteric viruses of nonhuman primates. Veter Pathol Suppl 19:33–43

    Google Scholar 

  4. Knowles NJ (2006) The picornavirus home page, http://www.picornaviridae.com/. Institute for Animal Health, Pirbright Laboratory, Pirbright, Woking, UK

  5. Nix WA, Oberste MS, Pallansch MA (2006) Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol 44:2698–2704

    Article  PubMed  CAS  Google Scholar 

  6. Nix WA, Jiang B, Maher K, Strobert E, Oberste MS (2008) Identification of enteroviruses in naturally infected captive primates. J Clin Microbiol 46:2874–2878

    Article  PubMed  CAS  Google Scholar 

  7. Norder H, Bjerregaard L, Magnius L, Lina B, Aymard M, Chomel J-J (2003) Sequencing of ‘untypable’ enteroviruses reveals two new types, EV-77 and EV-78, within human enterovirus type B and substitutions in the BC loop of the VP1 protein for known types. J Gen Virol 84:827–836

    Article  PubMed  CAS  Google Scholar 

  8. Oberste MS, Schnurr D, Maher K, al-Busaidy S, Pallansch MA (2001) Molecular identification of new picornaviruses and characterization of a proposed enterovirus 73 serotype. J Gen Virol 82:409–416

    PubMed  CAS  Google Scholar 

  9. Oberste MS, Maher K, Pallansch MA (2002) Molecular phylogeny and proposed classification of the simian picornaviruses. J Virol 76:1244–1251

    PubMed  CAS  Google Scholar 

  10. Oberste MS, Michele SM, Maher K, Schnurr D, Cisterna D, Junttila N, Uddin M, Chomel JJ, Lau CS, Ridha W, al-Busaidy S, Norder H, Magnius LO, Pallansch MA (2004) Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75. J Gen Virol 85:3205–3212

    Article  PubMed  CAS  Google Scholar 

  11. Oberste MS, Penaranda S, Maher K, Pallansch MA (2004) Complete genome sequences of all members of the species Human enterovirus A. J Gen Virol 85:1597–1607

    Article  PubMed  CAS  Google Scholar 

  12. Oberste MS, Maher K, Michele SM, Belliot G, Uddin M, Pallansch MA (2005) Enteroviruses 76, 89, 90 and 91 represent a novel group within the species Human enterovirus A. J Gen Virol 86:445–451

    Article  PubMed  CAS  Google Scholar 

  13. Oberste MS, Pallansch MA (2005) Enterovirus molecular detection and typing. Rev Med Microbiol 16:163–171

    Google Scholar 

  14. Oberste MS, Maher K, Williams AJ, Dybdahl-Sissoko N, Brown BA, Gookin MS, Penaranda S, Mishrik N, Uddin M, Pallansch MA (2006) Species-specific RT-PCR amplification of human enteroviruses: a tool for rapid species identification of uncharacterized enteroviruses. J Gen Virol 87:119–128

    Article  PubMed  CAS  Google Scholar 

  15. Oberste MS, Maher K, Nix WA, Michele SM, Uddin M, Schnurr D, al-Busaidy S, Akoua-Koffi C, Pallansch MA (2007) Molecular identification of 13 new enterovirus types, EV79–88, EV97, and EV100–101, members of the species Human Enterovirus B. Virus Res 128:34–42

    Article  PubMed  CAS  Google Scholar 

  16. Oberste MS, Maher K, Pallansch MA (2007) Complete genome sequences for nine simian enteroviruses. J Gen Virol 88:3360–3372

    Article  PubMed  CAS  Google Scholar 

  17. Oberste MS, Maher K, Pallansch MA (2007) Complete genome sequences for nine simian enteroviruses. J Gen Virol (in press)

  18. Pallansch MA, Roos R (2006) Enteroviruses: polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (eds) Fields virology. Lippincott Williams & Wilkins, Philadelphia, pp 839–893

    Google Scholar 

  19. Poyry T, Kinnunen L, Hyypia T, Brown B, Horsnell C, Hovi T, Stanway G (1996) Genetic and phylogenetic clustering of enteroviruses. J Gen Virol 77:1699–1717

    Article  PubMed  CAS  Google Scholar 

  20. Smura T, Blomqvist S, Paananen A, Vuorinen T, Sobotova Z, Bubovica V, Ivanova O, Hovi T, Roivainen M (2007) Enterovirus surveillance reveals proposed new serotypes and provides new insight into enterovirus 5’-untranslated region evolution. J Gen Virol 88:2520–2526

    Article  PubMed  CAS  Google Scholar 

  21. Smura TP, Junttila N, Blomqvist S, Norder H, Kaijalainen S, Paananen A, Magnius LO, Hovi T, Roivainen M (2007) Enterovirus 94, a proposed new serotype in human enterovirus species D. J Gen Virol 88:849–858

    Article  PubMed  CAS  Google Scholar 

  22. Stanway G, Brown F, Christian P, Hovi T, Hyypiä T, King AMQ, Knowles NJ, Lemon SM, Minor PD, Pallansch MA, Palmenberg AC, Skern T (2005) Picornaviridae. In: Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA (eds) Virus taxonomy eighth report of the international committee on the taxonomy of viruses. Elsevier Academic Press, Amsterdam, pp 757–778

    Google Scholar 

  23. Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599

    Article  PubMed  CAS  Google Scholar 

  24. Wang Y, Tu X, Humphrey C, McClure H, Jiang X, Qin C, Glass RI, Jiang B (2007) Detection of viral agents in fecal specimens of monkeys with diarrhea. J Med Primatol 36:101–107

    Article  PubMed  CAS  Google Scholar 

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Correspondence to M. Steven Oberste.

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The findings and conclusions in this report are those of the author(s) and do not necessarily represent the views of CDC.

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Oberste, M.S., Jiang, X., Maher, K. et al. The complete genome sequences for three simian enteroviruses isolated from captive primates. Arch Virol 153, 2117–2122 (2008). https://doi.org/10.1007/s00705-008-0225-4

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  • DOI: https://doi.org/10.1007/s00705-008-0225-4

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