Skip to main content

Advertisement

Log in

Anatomy and cervical dystonia

“Dysfunction follows form”

  • High Impact Review in Neuroscience, Neurology or Psychiatry - Review Article
  • Published:
Journal of Neural Transmission Aims and scope Submit manuscript

Abstract

At first glance, cervical dystonia might be an illustration of the well-known proposition “function follows form”. Nevertheless, cervical dystonia is a highly non-physiological condition, which cannot be reproduced by healthy subjects and does not respond to the usual physiological rules. “Dysfunction follows form” might be the most accurate aphorism to define cervical dystonia. Taking into account this situation and recent insights, the anatomic approach needs to be adapted to allow a better understanding of semiology and to improve botulinum toxin therapy. In this review dealing with a new approach to cervical dystonia, we develop some practical anatomical concepts concerning the head and neck complex. Knowledge of cervical spine and muscular dysfunctions in cervical dystonia is an essential stage in treating cervical dystonia patients with botulinum toxin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  • Bergman RA (2015) Function follows form. Clin Anat 28:956

    Article  PubMed  Google Scholar 

  • Buchthal F, Schmalbruch H (1980) Motor unit of mammalian muscle. Physiol Rev 60:90–142

    CAS  PubMed  Google Scholar 

  • Bull ML, De Freitas V, Vitti M (1984) Electromyographic study of the trapezius (pars superior) and levator scapulae muscles in the movements of the head. Electromyogr Clin Neurophysiol 24:217–223

    CAS  PubMed  Google Scholar 

  • Delnooz CC, Veugen LC, Pasman JW, Lapatki BG, van Dijk JP, van de Warrenburg BP (2014) The clinical utility of botulinum toxin injections targeted at the motor endplate zone in cervical dystonia. Eur J Neurol 21:1486–1492

    Article  CAS  PubMed  Google Scholar 

  • Falla D, Dall’Alba P, Rainoldi A, Merletti R, Jull G (2002) Location of innervation zones of sternocleidomastoid and scalene muscles—a basis for clinical and research electromyography applications. Clin Neurophysiol 113:57–63

    Article  CAS  PubMed  Google Scholar 

  • Hefter H, Blondin D, Kahlen U, Moll M, Antoch G, Schek J (2012) CT-guided intramuscular botulinum toxin A injections into the deep anterior neck muscles in patients with pure antecaput or antecollis. Basal Ganglia 2:97–101

    Article  Google Scholar 

  • Jinnah HA, Goodmann E, Rosen AR, Evatt M, Freeman A, Factor S (2016) Botulinum toxin treatment failures in cervical dystonia: causes, management, and outcomes. J Neurol 263:1188–1194

    Article  CAS  PubMed  Google Scholar 

  • Jost WH, Tatu L (2015) Selection of muscles for botulinum toxin injections in cervical dystonia. Mov Disord Clin Pract 2:224–226

    Article  Google Scholar 

  • Kapandji IA (2008) The physiology of the joints. Trunk and Spine, vol 3. Churchill Livingstone, London

    Google Scholar 

  • Lee JH, Lee BN, Han SH, An XC, Chung RH (2011) The effective zone of botulinum toxin a injections in the sternocleidomastoid muscle. Surg Radiol Anat 33:185–190

    Article  CAS  PubMed  Google Scholar 

  • Mayoux Benhamou MA, Revel M, Vallee C (1995) Surface electrodes are not appropriate to record selective myoelectric activity of splenius capitis in humans. Exp Brain Res 105:432–438

    Google Scholar 

  • Mayoux Benhamou MA, Revel M, Vallee C (1997) Selective electromyography of dorsal neck muscles in humans. Exp Brain Res 113:353–360

    Article  CAS  PubMed  Google Scholar 

  • Reichel G (2011) Cervical dystonia: a new phenomenological classification for botulinum toxin therapy. Basal Ganglia 1:5–12

    Article  Google Scholar 

  • Schramm A, Möbius C, Stark D, Huber D, Kohl Z (2014) Involvement of the obliquus capitis inferior muscle in dystonic head tremor. Mov Disord 29(S1):526

    Google Scholar 

  • Schramm A, Bäumer T, Fietzek U, Heitmann S, Walter U, Jost WH (2015) Relevance of sonography for botulinum toxin treatment of cervical dystonia: an expert statement. J Neural Transm 122:1457–1463

    Article  CAS  PubMed  Google Scholar 

  • Segal RL, Wolf SL, De Camp MJ, Chopp MT, English AW (1991) Anatomical partitioning of three multiarticular human muscles. Acta Anat 142:261–266

    Article  CAS  PubMed  Google Scholar 

  • Tabeke K, Vitti M, Basmajian JV (1974) The functions of semispinalis capitis and splenius capitis muscles: an electromyographic study. Anat Record 179:477–480

    Article  Google Scholar 

  • Tatu L, Parratte B (2016) Functional anatomy of the muscle. In: Roger B, Hamilton B, Skaf A (eds) Acute and chronic muscular pathology in the athlete. Springer, Heidelberg (in press)

    Google Scholar 

  • Tubbs RS (2015) Form follows function or does it? Clin Anat 28:955

    Article  PubMed  Google Scholar 

  • Windhorst U, Hamm TM, Stuart DG (1989) On the function of muscle and reflex partitioning. Behav Brain Sci 12:629–681

    Article  Google Scholar 

  • Wissel J, Kanovsky P, Ruzicka E, Bares M, Hortova H, Streitova H, Jech R, Roth J, Brenneis C, Müller J, Schnider P, Auff E, Richardson A, Poewe W (2001) Efficacy and safety of a standardised 500 unit dose of Dysport (clostridium botulinum toxin type a haemaglutinin complex) in a heterogeneous cervical dystonia population: results of a prospective, multicentre, randomised, double-blind, placebo-controlled, parallel group study. J Neurol 248:1073–1078

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. Tatu.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tatu, L., Jost, W.H. Anatomy and cervical dystonia. J Neural Transm 124, 237–243 (2017). https://doi.org/10.1007/s00702-016-1621-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00702-016-1621-7

Keywords

Navigation