Summary.
Genome-scans performed in schizophrenia families have provided evidence for region 6p24-21 where variability may confer susceptibility to schizophrenia. Recent studies have implicated that gene DTNBP1 (dysbindin) in this region is strongly associated with schizophrenia. In a family based association study we investigated three markers located in the untranslated region of the DTNBP1 gene: rs909706, rs1047631 and rs742106. The sample size of our study is 117 families. No biased transmission towards the disorder was detected by haplotype analysis using TRANSMIT.
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De Luca, V., Voineskos, D., Shinkai, T. et al. Untranslated region haplotype in dysbindin gene: analysis in schizophrenia. J Neural Transm 112, 1263–1267 (2005). https://doi.org/10.1007/s00702-005-0338-9
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DOI: https://doi.org/10.1007/s00702-005-0338-9