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Improvement of quality of life (QOL) between 1 and 3–4 years after traumatic brain injury (TBI) in ICU patients

  • Original Article - Brain Trauma
  • Published:
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Abstract

Background

Evaluation of changes in quality of life (QOL) in ICU patients several years after traumatic brain injury (TBI) is not well documented.

Methods

A prospective cohort study was conducted in all patients with TBI admitted between 2004 and 2008 to the ICU of Regional Hospital of Malaga (Spain). Functional status was evaluated by Glasgow Outcome Scale (GOS) and QOL by PAECC (Project for the Epidemiologic Analysis of Critical Care patients) questionnaire between 0 (normal QOL) to 29 points (worst QOL).

Results

A total of 531 patients. Median(Quartile1,Quartile 3) age: 35 (22, 56) years. After 3–4 years, 175 died (33%). Survivor QOL was deteriorated (median total PAECC score: 5 (0, 11) points) although 75.76% of patients who survived showed good functional situation (GOS normal or mild dysfunction). An improvement in QOL scores between 1 and 3–4 years was observed (median PAECC score differences between 3-4 years and 1 year: − 1(− 4, 0) points). QOL score improved during this interval of time: 62.6% of patients. Change in QOL was related by multivariate analysis to admission cranial–computed tomography scan (Marshall’s classification), age, and Injury Severity Score (ISS), with the biggest improvement seen in younger patients and with more severe ISS. Basic physiological activities were maintained in the majority of patients. Subjective aspects and working activities improved between 1 and 3–4 years but with a high proportion still impaired in these items after 3–4 years.

Conclusions

ICU patients with TBI after 1 year show improvement in QOL between 1 and 3–4 years, with the biggest improvement in QOL seen in younger patients and in those with more severe ISS.

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Acknowledgments

The authors would like to thank to Professor David Mendelow from Newcastle University who improved the final version of this paper with his invaluable advice.

Funding

This study was founded by public grant PI07/91032 of Instituto de Salud Carlos III, Ministerio de Sanidad, Spain.

Author information

Authors and Affiliations

  1. Intensive Care Unit, Hospital Regional Universitario, Málaga, Spain

    Miguel Angel Prieto-Palomino, Maria Dolores Arias-Verdú, Alfonso Muñoz-López, Juan Francisco Fernández-Ortega, Emilio Curiel-Balsera & Guillermo Quesada-Garcia

  2. Intensive Care Unit, Hospital Comarcal de la Axarquia Velez-Málaga, Málaga, Spain

    Monica Delange-VanDerKroft

  3. Neurosurgery Department, Hospital del Mar, Barcelona, Spain

    David Rodríguez-Rubio & Jesus Lafuente-Baraza

  4. Intensive Care Medicine, Hospital Infanta Margarita, Avenida de Gongora s/n., 14940, Cabra, Cordoba, Spain

    Eduardo Aguilar-Alonso

  5. Cardiology unit, Hospital Virgen de las Nieves, Granada, Spain

    Ricardo Rivera-López

  6. Intensive Care Unit, Complejo Hospitalario de Jaén, Jaen, Spain

    Maria Dolores Pola-GallegoDeGuzman & Ricardo Rivera-Fernández

Authors
  1. Miguel Angel Prieto-Palomino
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  2. Monica Delange-VanDerKroft
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  3. David Rodríguez-Rubio
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  4. Jesus Lafuente-Baraza
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  5. Eduardo Aguilar-Alonso
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  7. Maria Dolores Arias-Verdú
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  8. Maria Dolores Pola-GallegoDeGuzman
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  9. Alfonso Muñoz-López
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  10. Juan Francisco Fernández-Ortega
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  11. Emilio Curiel-Balsera
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  12. Guillermo Quesada-Garcia
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  13. Ricardo Rivera-Fernández
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Corresponding author

Correspondence to Eduardo Aguilar-Alonso.

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All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

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Prieto-Palomino, M.A., Delange-VanDerKroft, M., Rodríguez-Rubio, D. et al. Improvement of quality of life (QOL) between 1 and 3–4 years after traumatic brain injury (TBI) in ICU patients. Acta Neurochir 162, 1619–1628 (2020). https://doi.org/10.1007/s00701-020-04337-2

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  • DOI: https://doi.org/10.1007/s00701-020-04337-2

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