Skip to main content

Advertisement

SpringerLink
Log in

JEDI (jugular entrapment, dilated ventricles, intracranial hypertension) syndrome: a new clinical entity? A case report

  • Case Report - CSF Circulation
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Abstract

Patients with idiopathic intracranial hypertension are frequently obese women with normal/slit ventricles. Patients with high-pressure hydrocephalus, instead, present enlarged ventricles. We describe a 63-year-old woman with signs and symptoms of intracranial hypertension. Brain MRI revealed hydrocephalus. Venous Doppler ultrasound showed external compression of the omohyoid muscles on the internal jugular veins. During jugular vein decompression, intracranial pressure dropped from 18 to 6 mmHg. Patient is asymptomatic at 2-year follow-up, with decreased brain ventricles. These findings could represent a novel form of high-pressure hydrocephalus that can be successfully treated without a CSF shunt. We called this syndrome JEDI (jugular entrapment dilated ventricles intracranial hypertension).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Agren-Wilsson A, Eklund A, Koskinen LO, Bergenheim AT, Malm J (2005) Brain energy metabolism and intracranial pressure in idiopathic adult hydrocephalus syndrome. J Neurol Neurosurg Psychiatry 76:1088–1093. https://doi.org/10.1136/jnnp.2004.042838

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Bateman GA (2008) Arterial inflow and venous outflow in idiopathic intracranial hypertension associated with venous outflow stenoses. J Clin Neurosci 15:402–408. https://doi.org/10.1016/j.jocn.2007.03.018

    Article  PubMed  Google Scholar 

  3. Bhattathiri PS, Gregson B, Prasad KS, Mendelow AD, Investigators S (2006) Intraventricular hemorrhage and hydrocephalus after spontaneous intracerebral hemorrhage: results from the STICH trial. Acta Neurochir Suppl 96:65–68

    Article  CAS  PubMed  Google Scholar 

  4. De Bonis P, Mangiola A, Pompucci A, Formisano R, Mattogno P, Anile C (2013) CSF dynamics analysis in patients with post-traumatic ventriculomegaly. Clin Neurol Neurosurg 115:49–53. https://doi.org/10.1016/j.clineuro.2012.04.012

    Article  PubMed  Google Scholar 

  5. Jensen RH, Radojicic A, Yri H (2016) The diagnosis and management of idiopathic intracranial hypertension and the associated headache. Ther Adv Neurol Disord 9:317–326. https://doi.org/10.1177/1756285616635987

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Mollan SP, Davies B, Silver NC, Shaw S, Mallucci CL, Wakerley BR, Krishnan A, Chavda SV, Ramalingam S, Edwards J, Hemmings K, Williamson M, Burdon MA, Hassan-Smith G, Digre K, Liu GT, Jensen RH, Sinclair AJ (2018) Idiopathic intracranial hypertension: consensus guidelines on management. J Neurol Neurosurg Psychiatry. https://doi.org/10.1136/jnnp-2017-317440

  7. Sisini F, Tessari M, Menegatti E, Vannini ME, Gianesini S, Tavoni V, Gadda G, Gambaccini M, Taibi A, Zamboni P (2016) Clinical applicability of assessment of jugular flow over the individual cardiac cycle compared with current ultrasound methodology. Ultrasound Med Biol 42:1750–1763. https://doi.org/10.1016/j.ultrasmedbio.2016.03.002

    Article  PubMed  Google Scholar 

  8. Zamboni P, Menegatti E, Cittanti C, Sisini F, Gianesini S, Salvi F, Mascoli F (2016) Fixing the jugular flow reduces ventricle volume and improves brain perfusion. J Vasc Surg Venous Lymphat Disord 4:434–445. https://doi.org/10.1016/j.jvsv.2016.06.006

    Article  PubMed  Google Scholar 

  9. Zamboni P, Sisini F, Menegatti E, Taibi A, Malagoni AM, Morovic S, Gambaccini M (2013) An ultrasound model to calculate the brain blood outflow through collateral vessels: a pilot study. BMC Neurol 13:81. https://doi.org/10.1186/1471-2377-13-81

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neurosurgery, Department of Morphology, Surgery and Experimental Medicine, University Hospital S. Anna, Viale Aldo Moro 8, Cona, 44124, Ferrara, Italy

    Pasquale De Bonis, Michele Alessandro Cavallo, Giorgio Trapella & Alba Scerrati

  2. Section of Medical Physics, Department of Physics and Earth Sciences, University of Ferrara, Ferrara, Italy

    Pasquale De Bonis, Michele Alessandro Cavallo, Giorgio Trapella & Alba Scerrati

  3. Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy

    Erica Menegatti, Francesco Sisini & Paolo Zamboni

  4. Unit of Translational Surgery and Vascular Diseases Centre, University Hospital S. Anna, Ferrara, Italy

    Erica Menegatti, Francesco Sisini & Paolo Zamboni

Authors
  1. Pasquale De Bonis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Erica Menegatti
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Michele Alessandro Cavallo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Francesco Sisini
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Giorgio Trapella
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Alba Scerrati
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Paolo Zamboni
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Pasquale De Bonis.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Patient consent

The patient has consented to the submission of the case report for submission to the journal.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Preliminary results of this paper have been presented as a poster at the 66th annual Congress of the Italian Society of Neurosurgery (SINCh), Verona, 21–23 June 2017

This article is part of the Topical Collection on CSF Circulation

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

De Bonis, P., Menegatti, E., Cavallo, M.A. et al. JEDI (jugular entrapment, dilated ventricles, intracranial hypertension) syndrome: a new clinical entity? A case report. Acta Neurochir 161, 1367–1370 (2019). https://doi.org/10.1007/s00701-019-03908-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-019-03908-2

Keywords

Search

Navigation