Skip to main content

Advertisement

SpringerLink
Log in

Primary choroid plexus papilloma in the pituitary fossa: case report and literature review

  • Case Report
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Abstract

Choroid plexus papillomas are rare tumors of the central nervous system and are usually confined to the ventricular system. We illustrated a primary choroid plexus papilloma in the pituitary fossa. A 31-year-old female presented with amenorrhea and intermittent galactorrhoea, with no visual complaints in the last 2 years. Endocrine testing showed no hormone excess or deficiency of the pituitary and target glands, except for a higher prolactin level (56 ng/ml). A sharply circumscribed regular mass in the sellar region occupying the entire sella turcica and extending into the suprasellar cistern was demonstrated on MR imaging with gadolinium diethylenetriamine pentaacetic acid. The patient underwent an endonasal trans-sphenoidal approach. Complete microsurgical excision and complete preservation of the normal pituitary gland was achieved, with normal prolactin level. The histopathology showed that the lesion was a choroid plexus papilloma. Theories of the origin, the differential diagnosis, and treatment of the rare tumor are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

References

  1. Ang LC, Taylor AR, Bergin D, Kaufmann JCE (1990) An immunohistochemical study of papillary tumors in the central nervous system. Cancer 65:2712–2719

    Article  PubMed  CAS  Google Scholar 

  2. Beskonakli E, Cayli S, Bostanci U, Kulaçoglu S, Yalçinlar Y (1998) Choroid plexus papillomas of the posterior fossa: extraventricular extension, intraventricular and primary extraventricular location. Report of four cases. J Neurosurg Sci 42:37–40

    Article  PubMed  CAS  Google Scholar 

  3. Boldorini R, Panzarasa G, Girardi P, Monga G (2009) Primary choroids plexus papilloma of the sacral nerve roots. J Neurosurg Spine 10:51–53

    Article  PubMed  Google Scholar 

  4. Buurman H, Saeger W (2006) Subclinical adenomas in postmortem pituitaries: classification and correlations to clinical data. Eur J Endocrinol 154:753–758

    Article  PubMed  CAS  Google Scholar 

  5. Buxton N, Punt J (1997) Choroid plexus papilloma producing symptoms by secretion of cerebrospinal fluid. Pediatr Neurosurg 27:108–111

    Article  PubMed  CAS  Google Scholar 

  6. Casar Borota O, Jacobsen EA, Scheie D (2006) Bilateral atypical choroid plexus papillomas in cerebellopontine angles mimicking neurofibromatosis 2. Acta Neuropathol (Berl) 111:500–502

    Article  Google Scholar 

  7. Chow E, Reardon DA, Shah AB (1999) Pediatric choroid plexus neoplasms. Int J Radiat Oncol Bio Phys 44:249–254

    Article  CAS  Google Scholar 

  8. Coates TL, Hinshaw DB, Peckman N, Thompson JR, Hasso AN, Holshouser BA, Knierim DS (1989) Pediatric choroid plexus neoplasm MRI, CT and pathological correlation. Radiology 173:81–88

    PubMed  CAS  Google Scholar 

  9. García-Valtuille R, Abascal F, García-Valtuille AI, Pinto JI, Cerezal L, Sanz F, Trigueros F, Mazorra F (2000) Adult choroid plexus papilloma of the posterior fossa mimicking a hemangioblastoma. Case report. J Neurosurg 92:870–872

    Article  PubMed  Google Scholar 

  10. Girardot C, Boukobza M, Lamoureux JP, Sichez JP, Capelle L, Zouaoui A, Bencherif B, Metzger J (1990) Choroid plexus papillomas of the posterior fossa in adults: MR imaging and gadolinium enhancement. Report of four cases and review of the literature. J Neuroradiol 17:303–318

    PubMed  CAS  Google Scholar 

  11. Herbert J, Cavallaro T, Dwork AJ (1990) A marker for primary choroid plexus neoplasms. Am J Pathol 136:1317–1325

    PubMed  CAS  Google Scholar 

  12. Jinhu Y, Jianping D, Jun M, Hui S, Yepeng F (2007) Metastasis of a histologically benign choroid plexus papilloma: case report and review literature. J Neurooncol 83:47–52

    Article  PubMed  Google Scholar 

  13. Kawahara I, Tokunaga Y, Yagi N, Iseki M, Abe K, Hayashi T (2007) Papillary tumor of the pineal region. Neurol Med Chir (Tokyo) 47:568–571

    Article  Google Scholar 

  14. Kimura M, Takayasu M, Suzuki Y, Negoro M, Nagasaka T, Nakashima N, Sugita K (1992) Primary choroid plexus papilloma located in the suprasellar region: case report. Neurosurgery 31:563–566

    Article  PubMed  CAS  Google Scholar 

  15. Kumar R, Achari G, Banerji D, Jain VK, Chhabra DK (2002) Choroid plexus papilloma of the cerenellopontine angle. Neurol India 50:352–358

    PubMed  Google Scholar 

  16. Kurtkaya-Yapicier O, Scheithauer BW, Van Peteghem KP, Sawicki JE (2002) Unusual case of extradural choroid plexus papilloma of the sacral canal. Case report. J Neurosurg 97:102–105

    PubMed  Google Scholar 

  17. Ma YH, Ye K, Zhan RY, Wang LJ (2008) Primary choroid plexus papilloma of the sellar region. J Neurooncol 88:51–55

    Article  PubMed  Google Scholar 

  18. Mottl H, Koutecky J (1997) Treatment of spinal cord tumors in children. Med Pediatr Oncol 29:293–295

    Article  PubMed  CAS  Google Scholar 

  19. Mukhida K, Asa S, Gentili F, Shannon P (2006) Ependymoma of the pituitary fossa: case report and review literature. J Neurosurg 105:616–620

    Article  PubMed  Google Scholar 

  20. Nakano I, Kondo A, Iwasaki K (1997) Choroid plexus papilloma in the posterior third ventricle: case report. Neurosurgery 40:1279–1282

    Article  PubMed  CAS  Google Scholar 

  21. Noguchi A, Shiokawa Y, Kobayashi K, Saito I, Tsuchiya K, McMenomey SO, Delashaw JB (2004) Choroid plexus papilloma of the third ventricle in the fetus. Case illustration. J Neurosurg 100:224

    PubMed  Google Scholar 

  22. Okuyama T, Sohma T, Tsuchita H, Kitami K, Kohama I, Saito K (1995) Magnetic resonance imaging characteristics of choroid plexus papilloma in the fourth ventricle. Neurol Med Chir (Tokyo) 35:442–444

    Article  CAS  Google Scholar 

  23. Panizza BJ, Jackson A, Ramsden RT, Lye RH (1992) Choroid plexus papilloma of the cerebellopontine angle. Skull Base Surg 2:155–160

    Article  PubMed  CAS  Google Scholar 

  24. Park AH, Park HR, Chi JG (1996) Papillary ependymoma: its differential diagnosis from choroids plexus papilloma. J Korean Med Sci 11:415–421

    PubMed  CAS  Google Scholar 

  25. Pillai A, Rajeev K, Chandi S, Unnikrishnan M (2004) Intrinsic brainstem choroid plexus papilloma. Case report. J Neurosurg 100:1076–1078

    Article  PubMed  Google Scholar 

  26. Rickert CH, Paulus W (2001) Tumors of choroid plexus. Microsc Res Tech 52:104–111

    Article  PubMed  CAS  Google Scholar 

  27. Rotondo F, Kovacs K, Scheithauer BW, Horvath E, Bell CD, Lloyd RV, Cusimano M (2008) Immunohistochemical expression of SNAP-25 protein in adenomas of the human pituitary. Appl Immunohistochem Mol Morphol 16:477–481

    Article  PubMed  CAS  Google Scholar 

  28. Sameshima T, Tanikawa R, Sugimura T, Izumi N, Seki T, Maeda T, Tsuboi T, Hashimoto M, Kimura T, Nabeshima K (2010) Choroid plexus papilloma originating in the sellar turcica: case report. Neurol Med Chir (Tokyo) 50:144–146

    Article  Google Scholar 

  29. Sampath S, Nitin G, Yasha TC, Chandramouli BA, Devi BI, Kovoor JM (2008) Does choroids plexus tumor differ with age? Br J Neurosurg 22:373–388

    Article  PubMed  CAS  Google Scholar 

  30. Sarkar C, Sharma MC, Gaikwad S, Sharma C, Singh VP (1999) Choroid plexus papilloma: a clinicopathological study of 23 cases. Surg Neurol 52:37–39

    Article  PubMed  CAS  Google Scholar 

  31. Stafrace S, Molloy J (2008) Extraventricular choroid plexus papilloma in a neonate. Pediatr Radiol 38:593

    Article  PubMed  Google Scholar 

  32. Steven DA, McGinn GJ, McClarty BM (1996) A choroid plexus papilloma arising from an incidental pineal cyst. AJNR Am J Neuroradiol 17:939–942

    PubMed  CAS  Google Scholar 

  33. Tacconi L, Delfini R, Cantore G (1996) Choroid plexus papillomas, consideration of a surgical series of 33 cases. Acta Neurochir 138:802–811

    Article  CAS  Google Scholar 

  34. Thomson S, Chakrabarty A, Marks P (2001) Ependymoma of neurohypophysis. Br J Neurosurg 15:277–278

    Article  PubMed  CAS  Google Scholar 

  35. Winer JB, Lidov H, Scaravilli F (1989) An ependymoma involving the pituitary. J Neurol Neurosurg Psychiatry 52:1443–1444

    Article  PubMed  CAS  Google Scholar 

Download references

Conflicts of interest

None.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China

    Liu-Guan Bian, Qing-Fang Sun, Hong Jiang, Yue-Hao Sun & Jian-Kang Shen

  2. Department of Pathology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China

    Hua-Cheng Wu

Authors
  1. Liu-Guan Bian
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Qing-Fang Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hua-Cheng Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hong Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yue-Hao Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jian-Kang Shen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Liu-Guan Bian.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bian, LG., Sun, QF., Wu, HC. et al. Primary choroid plexus papilloma in the pituitary fossa: case report and literature review. Acta Neurochir 153, 851–857 (2011). https://doi.org/10.1007/s00701-010-0884-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-010-0884-2

Keywords

Search

Navigation