Abstract
Purpose
Minimally invasive percutaneous single trajectory stereotactic radiofrequency amygdalohippocampectomy was used to treat mesial temporal lobe epilepsy (MTLE). The aim of the study was to evaluate complications and effectiveness of this procedure.
Materials and methods
A group of 51 patients with MTLE was treated using stereotactic thermo-lesion of amygdalohippocampal complex under local anaesthesia. The target was reached through the occipital approach with a single trajectory using MRI stereotactic localisation. Thermocoagulation of the amygdalohippocampal complex was planned according to the individual anatomy of each patient. Amygdalohippocampectomy was performed using a string electrode with a 10-mm active tip, and 16–38 lesions (median = 25) were performed in all patients along the 30- to 45-mm trajectory (median = 35) in the amygdalohippocampal complex.
Results
The procedure was well tolerated by all patients with no severe permanent morbidity; meningitis was recorded in two patients (4%), hematoma was detected in four patients, clinically insignificant in three of them, and one patient required temporary ventricular drainage (2%). Thirty-two patients were followed up over at least 2 years, and the clinical outcomes were evaluated by Engel’s classification; 25 of them (78%) were Engel I, five (16%) were Engel II, and two (6%) were Engel IV.
Conclusions
Stereotactic amygdalohippocampectomy is a minimally invasive procedure with low morbidity and good results that can be the method of choice in selected patients with MTLE.
Similar content being viewed by others
References
Awad IA, Katz A, Hahn JF, Kong AK, Ahl J, Luders H (1989) Extend of resection in temporal lobectomy for epilepsy. I. Interobserver analysis and correlation with seizure outcome. Epilepsia 30:756–762
Bartolomei F, Hayashi M, Tamura M, Rey M, Fischer C, Chauvel P, Régis J (2008) Long-term efficacy of gamma knife radiosurgery in mesial temporal lobe epilepsy. Neurology 70:1658–1663
Blume TW, Parrent AG, Kaibara M (1997) Stereotactic amygdalohippocampectomy and mesial temporal spikes. Epilepsia 38(8):930–936
Catenoix H, Mauguiere F, Guenot M, Ryvlin P, Bissery A, Sindou M, Isnard J (2008) SEEG-quided thermocoagulations: a palliative treatment of nonoperable partial epilepsies. Neurology 71:1719–1726
Clusmann H, Schramm J, Kral T, Helmstaedter C, Ostertun B, Fimmers R, Haun D, Elger CE (2002) Prognostic factors and outcome after different types of resection for temporal lobe epilepsy. J Neurosurg 97:1131–1141
Dbaly V (2004) Epilepsy surgery of adults. Grada, Prague (in Czech)
Engel J Jr, Van Ness PC, Rasmussen TB (1993) Outcome with respect to epileptic seizures. In: Engel J Jr (ed) Surgigal treatment of the epilepsies, 2nd edn. Raven, New York, pp 609–621
Falconer MA (1965) The surgical treatment of temporal lobe epilepsy. Nurochirurgia 8:161–172
Jack CR Jr, Sharbrough FW, Marsh WR (1988) Use of MR imaging for quantitative evaluation of resection for temporal lobe epilepsy. Radiology 169:463–468
Kalina M, Liscak R, Vojtech Z, Adámkova E, Prochazka T, Mareckova I, Vladyka V (2007) Stereotactic amygdalohippocampectomy for temporal lobe epilepsy: promising results in 16 patients. Epileptic Disord 9(Suppl 1):68–77
Malikova H, Vojtech V, Liscak R, Prochazka T, Vymazal J, Vladyka V, Keller J, Kalina M (2009) Stereotactic radiofrequency amygdalohippocampectomy for the treatment of mesial temporal lobe epilepsy: correlation of MRI with clinical seizure outcome. Epilepsy Res 83:235–242
Malikova H, Vojtech Z, Liscak R, Prochazka T, Vymazal J, Mareckova I, Kalina M, Dbaly V, Keller J, Vladyka V (2010) Microsurgical and stereotactic radiofrequency amygdalohippocampectomy for the treatment of mesial temporal lobe epilepsy: different volume reduction, similar clinical seizure control. Stereotact Funct Neurosurg 88:42–50
McKhann GM 2nd, Schoenfeld-McNeill J, Born DE, Haglund MM, Ojemann GA (2000) Intraoperative hippocampal electrocorticography to predict the extend of hippocampal resection in temporal lobe epilepsy surgery. J Neurosurg 93:44–52
Nadvornik P, Sramka M, Gajdosova D, Kokavek M (1975) Longitudinal hippocampectomy. A new stereotactic approach to the gyrus hipopocampi. Confin Neurol 37:244–248
Niemeyer P (1958) The transventricular amygdalohippocampectomy in temporal lobe epilepsy. In: Baldwin M, Bailey P (eds) Temporal lobe epilepsy. Charles C Thomas, Springfield, pp 461–482
Novak K, Czech T, Prayer D, Dietrich W, Serles W, Lehr S, Baumgartner C (2002) Individual variations in the sulcal anatomy of the basal temporal lobe and its relevance for epilepsy surgery: an anatomical study performed using magnetic resonance imaging. J Neurosurg 96:464–473
Noulhiane M, Samson S, Clemenceau S, Dormont D, Baulac M, Hasboun D (2006) A volumetric MRI study of the hippocampus and the parahippocampal region after unilateral medial temporal lobe resection. J Neurosci Methods 156:293–304
Parrent AG, Blume WT (1999) Stereotactic amygalohippocampotomy for the treatment of medial temporal lobe epilepsy. Epilepsia 40:1408–1416
Regis J, Peragut JC, Rey M, Samson Y, Levrier O, Porcheron D, Regis H, Sedan R (1995) First selective amygdalohippocampal radiosurgery for “mesial temporal lobe epilepsy”. Stereotact Funct Neurosurg 64(Suppl 1):193–201
Regis J, Rey M, Bartolomei F, Vladyka V, Liscak R, Schrottner O, Pendl G (2004) Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study. Epilepsia 45(5):504–515
Schramm J (2008) Temporal lobe epilepsy surgery and the quest for optimal extend of resection: a review. Epilepsia 49(8):1296–1307
Siegel AM, Wieser HG, Wichmann W, Yasargil GM (1990) Relationships between MR-imaged total amount of tissue removed, resection scores of specific mediobasal limbic subcompartments and clinical outcome following selective amygdalohippocampectomy. Epilepsy Res 6:56–65
Spencer D, Inserni J (1991) Temporal lobectomy. In: Luders H (ed) Epilepsy surgery. Raven, New York, pp 533–545
Talairach J, Bancaud J, Szikla G, Bonis A, Geier S, Vedrenne C (1974) New approach to the neurosurgery of epilepsy. Stereotaxic methodology and therapeutic results. 1. Introduction and history. Neurochirurgie 20(Suppl 1):1–240
Talairach J, David M, Tournoux F (1958) L’exploration chirurgical stéréotaxique du lobe temporal dans l’épilepisie temporal. Masson, Paris
Talaraich J, Szikla G (1965) Destruction partielle amygdalo-hippocampique per l’yttrium 90 dans la traitment de certaines epilepsies á expression rhinencephaliue. Neurochirurgie 11:236–240
Vajkoczy P, Krakow K, Stodieck S, Pohlmann-Eden B, Schmiedek P (1998) Modified approach for the selective treatment of temporal lobe epilepsy: transsylvian–transcisternal mesial en bloc resection. J Neurosurg 88:855–862
Vladyka V (1978) Tactics in surgical treatment epilepsy and its realization in cases of temporal epilepsy. Cesk Slov Neurol N 41:95–106
Vojtech Z, Vladyka V, Kalina M, Nespor E, Seltenreichova K, Semnicka J, Liscak R (2009) The use of radiosurgery for the treatment of mesial temporal lobe epilepsy and long-term results. Epilepsia 50(9):2061–2071
Yasargil MG, Teddy PJ, Roth P (1985) Selective amygdalohippocampectomy. Operative anatomy and surgical technique. Adv Tech Stand Neurosurg 12:93–123
Yasargil MG, Wieser HG, Valavanis A, von Ammon K, Roth P (1993) Surgery and results of selective amygdala–hippocampectomy in one hundred patients with nonlesional limbic epilepsy. Neurosurg Clin N Am 4:243–261
Wyler AR, Hermann BP, Somes G (1995) Extent of mesial temporal resection on outcome from anterior temporal lobectomy: a randomized prospective study. Neurosurgery 37:982–990
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Liscak, R., Malikova, H., Kalina, M. et al. Stereotactic radiofrequency amygdalohippocampectomy in the treatment of mesial temporal lobe epilepsy. Acta Neurochir 152, 1291–1298 (2010). https://doi.org/10.1007/s00701-010-0637-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00701-010-0637-2