Summary
Percutaneous vertebroplasty (PV) is one of the alternative treatments for vertebral fractures. Reported significant complications include pain, radiculopathy, spinal cord compression, pulmonary embolism, infection and rib fractures. In this report, we highlight intradural cement leakage which is a rare complication of the procedure.
A 49 year old man with a T12 compression fracture due to multiple myeloma was referred to the neurosurgery department from the orthopaedics and traumatology clinic after developing a right lower limb weakness following percutaneous vertebroplasty with polymethylmethacrylate. An urgent thoraco-lumbar magnetic resonance imaging was performed. The T1 and T2-weighted images demonstrated intradural extramedullary and epidural cement leakages which were hypointense on both sequences. Total laminectomy was performed at T12 and L1 and two epidural cement collections were excised on the right. Then, a dural incision from T12 to the body of L1 was done and cement material seen in front of the rootlets excised without any nerve injury. The patient was discharged after a week and referred to the haematology clinic for additional therapy of multiple myeloma. Although the cement leakage was extensive, the right leg weakness improved significantly and he began to walk with assistance 3 months later.
Good quality image monitoring and clear visualisation of cement are essential requirements for PV using polymethylmethacrylate to prevent this complication from the treatment.
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References
G Bacci S Ferrari A Longhi D Donati E Barbieri C Forni F Bertoni M Manfrini S Giacomini P Bacchini (2004) ArticleTitleRole of surgery in local treatment of Ewing’s sarcoma of the extremities in patients undergoing adjuvant and neoadjuvant chemotherapy Oncol Rep 11 111–120 Occurrence Handle14654912
JD Barr MS Barr TJ Lemley RM McCann (2000) ArticleTitlePercutaneous vertebroplasty for pain relief and spinal stabilisation Spine 25 923–928 Occurrence Handle10767803 Occurrence Handle10.1097/00007632-200004150-00005 Occurrence Handle1:STN:280:DC%2BD3c3jt1Shuw%3D%3D
YJ Chen TS Tan WH Chen CC Chen TS Lee (2006) ArticleTitleIntradural cement leakage: a devastatingly rare complication of vertebroplasty Spine 31 IssueID12 E379–E382 Occurrence Handle16721284 Occurrence Handle10.1097/01.brs.0000219495.57470.67
JP Constans E de Devitis R Donzelli R Spaziante JF Meder C Haye (1983) ArticleTitleSpinal metastases with neurological manifestations. Review of 600 Cases J Neurosurg 59 111–118 Occurrence Handle6864265 Occurrence Handle1:STN:280:DyaL3s3ktVOlsw%3D%3D
A Cotten F Dewatre B Cortet R Assakere D Leblond B Duquesnoy P Chastanet J Clarisse (1996) ArticleTitlePercutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methacrylate at clinical follow-up Radiology 200 525–530 Occurrence Handle8685351 Occurrence Handle1:STN:280:DyaK283psVGqsQ%3D%3D
H Deramond C Depriester P Galibert D Le Gars (1998) ArticleTitlePercutaneous vertebroplasty with polymethylmethacrylte: technique, indications and results Radiol Clin North Am 36 533–546 Occurrence Handle9597071 Occurrence Handle10.1016/S0033-8389(05)70042-7 Occurrence Handle1:STN:280:DyaK1c3lvFemuw%3D%3D
RJ Dunn SuffixJr WA Kelly RN Wohns JF Howe (1980) ArticleTitleSpinal epidural neoplasia: a 15 year review of results of surgical therapy J Neurosurg 52 47–51 Occurrence Handle7350280
W Enneking (1983) Spine WF Enneking (Eds) Musculoskeletal Tumor Surgery Livingstone Churchill New York 303–354
JW Fielding RN Pyle SuffixJr VG Fietti SuffixJr (1979) ArticleTitleAnterior cervical vertebral body resection and bone grafting for benign and malignant tumours. A survey under the auspices of the Cervical Spine Research Society J Bone Joint Surg 61 251–253 Occurrence Handle370119 Occurrence Handle1:STN:280:DyaE1M7jtVGisw%3D%3D
SR Garfin HA Yuan MA Reiley (2001) ArticleTitleNew technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures Spine 26 1511–1515 Occurrence Handle11462078 Occurrence Handle10.1097/00007632-200107150-00002 Occurrence Handle1:STN:280:DC%2BD3Mvht1Onsw%3D%3D
Jahvant P (2006) Percutaneous vertebroplasty. eMedicine. June Issue. Retrieved [December 6, 2007] from http://www.emedicine.com/neuro/topic682.htm
JD Laredo A el Quessar P Bossard V Vuillemin-Bodaghi (2001) ArticleTitleVertebral tumours and pseudotumours Radiol Clin Noth Am 39 137–163 Occurrence Handle10.1016/S0033-8389(05)70267-0 Occurrence Handle1:STN:280:DC%2BD3M7psVCiuw%3D%3D
JD Laredo B Hamze (2005) ArticleTitleComplications of percutaneous vertebroplasty and their prevention Semin Ultrasound CT MR 26 65–80 Occurrence Handle15856808 Occurrence Handle10.1053/j.sult.2005.02.003
BJ Lee SR Lee TY Yoo (2002) ArticleTitleParaplegia as a complication of percutaneous vertebroplasty with polymethylmethacrylate: a case report Spine 27 IssueID19 E419–E422 Occurrence Handle12394938 Occurrence Handle10.1097/00007632-200210010-00022
JM Mathis JB Barr SM Belkoff MS Barr ME Jensen H Deramond (2001) ArticleTitlePercutaneous vertebroplasty: a developing standard of care for vertebral compression fractures Am J Neuroradiol 22 373–381 Occurrence Handle11156786 Occurrence Handle1:STN:280:DC%2BD3M7ntFCmsA%3D%3D
Pilitsis JG, Rengachary SS (2001) The role of vertebroplasty in metastatic vertebral disease. Neurosurg Focus 11(6): Article 9. Retrieved [December 6, 2007] from: http://www.aans.org/education/journal/neurosurgical/dec01/11-6-9.pdf
TA Predey LE Sewall SJ Smith (2002) ArticleTitlePercutaneous vertebroplasty: new treatment for vertebral compression fractures Am Fam Physician 66 IssueID4 611–615 Occurrence Handle12201552
S Shapiro T Abel S Purvines (2003) ArticleTitleSurgical removal of epidural and intradural polymethylmethacrylate extravasation complicating percutaneous vertebroplasty for an osteoporotic lumbar compression fracture: case report J Neurosurg (Spine 1) 98 90–92 Occurrence Handle10.3171/spi.2003.98.1.0090
MMH Teng H Cheng DMT Ho CY Chang (2006) ArticleTitleIntraspinal leakage of bone cement after vertebroplasty: a report of 3 cases Am J Neuroradiol 27 224–229 Occurrence Handle16418389 Occurrence Handle1:STN:280:DC%2BD28%2FjtVSjuw%3D%3D
A Weill J Chiras JM Simon M Rose T Sola-Martinez E Enkaoua (1996) ArticleTitleSpinal metastases: indications for and results of percutaneous injection of acrylic surgical cement Radiology 199 241–247 Occurrence Handle8633152 Occurrence Handle1:STN:280:DyaK283gtF2jtA%3D%3D
Workers’ Compensation Board of British Columbia Evidence Based Practice Group (2003) Percutaneous vertebroplasty for pain relief in the management of compressive vertebral fractures. Retrieved [December 6, 2007] from http://www.worksafebc.com/health_care_providers/Assets/PDF/percutaneous_vertebroplasty.pdf
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Correspondence: Hakan Sabuncuoğlu, Koza Sokak No: 72/36, İkizler Sitesi 06700, Gaziosmanpaşa, Ankara, Turkey.
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Sabuncuoğlu, H., Dinçer, D., Güçlü, B. et al. Intradural cement leakage: a rare complication of percutaneous vertebroplasty. Acta Neurochir (Wien) 150, 811–815 (2008). https://doi.org/10.1007/s00701-008-1503-3
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DOI: https://doi.org/10.1007/s00701-008-1503-3