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Intracranial meningioma containing metastatic colon carcinoma

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Summary

Tumour-to-tumour metastasis is a rare pathological entity. Meningioma is the most common intracranial tumour to host metastases, the majority of which arise from breast and lung cancers. We present the first report of a colonic cancer metastasis within an intracranial meningioma.

A 76-year-old woman presented with a one month history of partial seizures. Her medical history included resection of an adenocarcinoma of the descending colon followed by adjuvant chemotherapy 1 year before our evaluation. Magnetic resonance imaging revealed a homogeneously enhancing lesion in the right frontal convexity.

A well capsulated tumour attached to the frontal dura was surgically removed. The pathological examination demonstrated a mixture of fibrous meningioma and colloid adenocarcinoma. Possible explanations for the development of a cohesive chimeric mass of composite pathology are investigated.

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Authors and Affiliations

  1. Neurosurgical Department, University of Florence, Firenze, Italy

    N. Benedetto, P. Perrini, A. Scollato & N. Di Lorenzo

  2. Department of Human Pathology and Oncology, University of Florence, Firenze, Italy

    A. M. Buccoliero

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  1. N. Benedetto
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  2. P. Perrini
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  3. A. Scollato
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  4. A. M. Buccoliero
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  5. N. Di Lorenzo
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Benedetto, N., Perrini, P., Scollato, A. et al. Intracranial meningioma containing metastatic colon carcinoma. Acta Neurochir (Wien) 149, 799–803 (2007). https://doi.org/10.1007/s00701-007-1239-5

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  • DOI: https://doi.org/10.1007/s00701-007-1239-5

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