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Treatment of vestibular schwannomas. Why, when and how?

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Summary

Sporadic vestibular schwannoma (VS) causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. In many cases, the tumour size may remain unchanged for many years following diagnosis, which is typically made by MRI. In the majority of cases the tumour is small, leaving the clinician and patient with the options of either serial scanning or active treatment by gamma knife radiosurgery (GKR) or microneurosurgery. Despite the vast number of published treatment reports, comparative studies are few, and evidence is no better than class III (May, 2006). The predominant clinical endpoints of VS treatment include tumour control, facial nerve function and hearing preservation. Less focus has been put on symptom relief and health-related quality of life (QOL). It is uncertain if treating a small tumour leaves the patient with a better chance of obtaining relief from future hearing loss, vertigo or tinnitus than by observing it without treatment. Recent data indicate that QOL is reduced in untreated VS patients, and may differ between patients who have been operated and patients treated with GKR. In the present paper we review the natural course and complaints of untreated VS patients, and the treatment alternatives and results. Furthermore, we review the literature concerning quality of life in patients with VS. Finally, we present our experience with a management strategy applied to more than 300 cases since 2001.

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References

  • G Andersson L Ekvall A Kinnefors G Nyberg H Rask-Andersen (1997) ArticleTitleEvaluation of quality of life and symptoms after translabyrinthine acoustic neuroma surgery Am J Otol 18 421–426 Occurrence Handle1:STN:280:DyaK2sznslyrsg%3D%3D Occurrence Handle9233480

    CAS  PubMed  Google Scholar 

  • G Andersson A Kinnefors L Ekvall H Rask-Andersen (1997) ArticleTitleTinnitus and translabyrinthine acoustic neuroma surgery Audiol Neurootol 2 403–409 Occurrence Handle1:STN:280:DyaK1c%2Fks1CgsA%3D%3D Occurrence Handle9390844 Occurrence Handle10.1159/000259265

    Article  CAS  PubMed  Google Scholar 

  • MA Arriaga DA Chen (2001) ArticleTitleFacial function in hearing preservation acoustic neuroma surgery Arch Otolaryngol Head Neck Surg 127 543–546 Occurrence Handle1:STN:280:DC%2BD3M3ptlKnsA%3D%3D Occurrence Handle11346430

    CAS  PubMed  Google Scholar 

  • A Axelsson A Ringdahl (1989) ArticleTitleTinnitus — a study of its prevalence and characteristics Br J Audiol 23 53–62 Occurrence Handle1:STN:280:DyaL1M3gsl2rsQ%3D%3D Occurrence Handle2784987

    CAS  PubMed  Google Scholar 

  • DM Baguley DA Moffat DG Hardy (1992) ArticleTitleWhat is the effect of translabyrinthine acoustic schwannoma removal upon tinnitus? J Laryngol Otol 106 329–331 Occurrence Handle1:STN:280:DyaK38zgvVKruw%3D%3D Occurrence Handle1613345

    CAS  PubMed  Google Scholar 

  • ME Bari DM Forster AA Kemeny L Walton D Hardy JR Anderson (2002) ArticleTitleMalignancy in a vestibular schwannoma. Report of a case with central neurofibromatosis, treated by both stereotactic radiosurgery and surgical excision, with a review of the literature Br J Neurosurg 16 284–289 10.1080/02688690220148888 Occurrence Handle1:STN:280:DC%2BD38vkslamsQ%3D%3D Occurrence Handle12201399

    CAS  PubMed  Google Scholar 

  • N Bateman TP Nikolopoulos K Robinson GM O’Donoghue (2000) ArticleTitleImpairments, disabilities, and handicaps after acoustic neuroma surgery Clin Otolaryngol Allied Sci 25 62–65 10.1046/j.1365-2273.2000.00326.x Occurrence Handle1:STN:280:DC%2BD3c3isFejug%3D%3D Occurrence Handle10764238

    CAS  PubMed  Google Scholar 

  • CD Bauch SG Lynn DE Williams MW Mellon AL Weaver (2003) ArticleTitleTinnitus impact: three different measurement tools J Am Acad Audiol 14 181–187 Occurrence Handle12940702

    PubMed  Google Scholar 

  • I Baumann J Polligkeit G Blumenstock PS Mauz IM Zalaman MM Maassen (2005) ArticleTitleQuality of life after unilateral acoustic neuroma surgery via middle cranial fossa approach Acta Otolaryngol 125 585–591 Occurrence Handle16076706

    PubMed  Google Scholar 

  • JB Bederson K von Ammon WW Wichmann MG Yasargil (1991) ArticleTitleConservative treatment of patients with acoustic tumors Neurosurgery 28 646–650 10.1097/00006123-199105000-00002 Occurrence Handle1:STN:280:DyaK3MzktlSqtA%3D%3D Occurrence Handle1876241

    CAS  PubMed  Google Scholar 

  • KI Berliner C Shelton WE Hitselberger WM Luxford (1992) ArticleTitleAcoustic tumors: effect of surgical removal on tinnitus Am J Otol 13 13–17 Occurrence Handle1:STN:280:DyaK383os1emtw%3D%3D Occurrence Handle1598977

    CAS  PubMed  Google Scholar 

  • SA Betchen J Walsh KD Post (2003) ArticleTitleSelf-assessed quality of life after acoustic neuroma surgery J Neurosurg 99 818–823 Occurrence Handle14609159

    PubMed  Google Scholar 

  • A Bottomley H Flechtner F Efficace V Vanvoorden C Coens P Therasse G Velikova J Blazeby E Greimel (2005) ArticleTitleHealth related quality of life outcomes in cancer clinical trials Eur J Cancer 41 1697–1709 10.1016/j.ejca.2005.05.007 Occurrence Handle1:STN:280:DC%2BD2Mvjt1CjtA%3D%3D Occurrence Handle16043345

    CAS  PubMed  Google Scholar 

  • RJ Briggs G Fabinyi AH Kaye (2000) ArticleTitleCurrent management of acoustic neuromas: review of surgical approaches and outcomes J Clin Neurosci 7 521–526 10.1054/jocn.2000.0728 Occurrence Handle1:STN:280:DC%2BD3MzgsVWgsw%3D%3D Occurrence Handle11029233

    CAS  PubMed  Google Scholar 

  • RJ Briggs WM Luxford JS Atkins WE Hitselberger (1994) ArticleTitleTranslabyrinthine removal of large acoutsic neurinomas Neurosurgery 34 785–790 10.1097/00006123-199405000-00001 Occurrence Handle1:STN:280:DyaK2czivFamtQ%3D%3D Occurrence Handle8052375

    CAS  PubMed  Google Scholar 

  • AM Bronstein (2004) ArticleTitleVision and vertigo: some visual aspects of vestibular disorders J Neurol 251 381–387 10.1007/s00415-004-0410-7 Occurrence Handle15083281

    PubMed  Google Scholar 

  • CA Buchman DA Chen P Flannagan JE Wilberger JC Maroon (1996) ArticleTitleThe learning curve for acoustic tumor surgery Laryngoscope 106 1406–1411 10.1097/00005537-199611000-00019 Occurrence Handle1:STN:280:DyaK2s%2Fnt1SktQ%3D%3D Occurrence Handle8914910

    CAS  PubMed  Google Scholar 

  • A Cohen B Modan (1968) ArticleTitleSome epidemiologic aspects of neoplastic diseases in Israeli immigrant population. 3. Brain tumors Cancer 22 1323–1328 10.1002/1097-0142(196811)22:6<1323::AID-CNCR2820220632>3.0.CO;2-H Occurrence Handle1:STN:280:DyaF1M%2FptFWnsw%3D%3D Occurrence Handle4303168

    CAS  PubMed  Google Scholar 

  • MM Collins IJ Johnson E Clifford JP Birchall GM O’Donoghue (2003) ArticleTitlePostural stability of preoperative acoustic neuroma patients assessed by sway magnetometry: are they unsteady? Laryngoscope 113 640–642 10.1097/00005537-200304000-00010 Occurrence Handle12671420

    PubMed  Google Scholar 

  • SE Coulson GR Croxson RD Adams NJ O’Dwyer (2005) ArticleTitleReliability of the “Sydney”, “Sunnybrook”, and “House Brackmann” facial grading systems to assess voluntary movement and synkinesis after facial nerve paralysis Otolaryngol Head Neck Surg 132 543–549 10.1016/j.otohns.2005.01.027 Occurrence Handle15806042

    PubMed  Google Scholar 

  • JJ Cross D Baguley NM Antoun D Moffat AT Prevost (2006) ArticleTitleReproducibility of volume measurements of vestibular schwannomas — a preliminary study Clin Otolaryngol 31 123–129 10.1111/j.1749-4486.2006.01161.x Occurrence Handle1:STN:280:DC%2BD283hsVyqug%3D%3D Occurrence Handle16620331

    CAS  PubMed  Google Scholar 

  • MJ da Cruz DA Moffat DG Hardy (2000) ArticleTitlePostoperative quality of life in vestibular schwannoma patients measured by the SF36 Health Questionnaire Laryngoscope 110 151–155 10.1097/00005537-200001000-00027 Occurrence Handle1:STN:280:DC%2BD3c7htVKmsA%3D%3D Occurrence Handle10646732

    CAS  PubMed  Google Scholar 

  • V Darrouzet J Martel V Enee JP Bebear J Guerin (2004) ArticleTitleVestibular schwannoma surgery outcomes: our multidisciplinary experience in 400 cases over 17 years Laryngoscope 114 681–688 10.1097/00005537-200404000-00016 Occurrence Handle15064624

    PubMed  Google Scholar 

  • HG Deen MJ Ebersold SG Harner CW Beatty MS Marion RE Wharen JD Green L Quast (1996) ArticleTitleConservative management of acoustic neuroma: an outcome study Neurosurgery 39 260–264 10.1097/00006123-199608000-00005 Occurrence Handle1:STN:280:DyaK28vivFGlsw%3D%3D Occurrence Handle8832662

    CAS  PubMed  Google Scholar 

  • M Dieterich (2004) ArticleTitleDizziness Neurologist 10 154–164 10.1097/01.nrl.0000126586.29463.c8 Occurrence Handle15140275

    PubMed  Google Scholar 

  • MJ Ebersold SG Harner CW Beatty CM Harper SuffixJr LM Quast (1992) ArticleTitleCurrent results of the retrosigmoid approach to acoustic neurinoma J Neurosurg 76 901–909 Occurrence Handle1:STN:280:DyaK383mvFSjtQ%3D%3D Occurrence Handle1588422

    CAS  PubMed  Google Scholar 

  • AJ Elsmore ND Mendoza (2002) ArticleTitleThe operative learning curve for vestibular schwannoma excision via the retrosigmoid approach Br J Neurosurg 16 448–455 10.1080/0268869021000030249 Occurrence Handle1:STN:280:DC%2BD38jjsV2gsA%3D%3D Occurrence Handle12498487

    CAS  PubMed  Google Scholar 

  • C Fahy TP Nikolopoulos GM O’Donoghue (2002) ArticleTitleAcoustic neuroma surgery and tinnitus Eur Arch Otorhinolaryngol 259 299–301 Occurrence Handle12115076

    PubMed  Google Scholar 

  • H Fielder SW Denholm RA Lyons CP Fielder (1996) ArticleTitleMeasurement of health status in patients with vertigo Clin Otolaryngol Allied Sci 21 124–126 Occurrence Handle1:STN:280:DyaK28zivVKhug%3D%3D Occurrence Handle8735395

    CAS  PubMed  Google Scholar 

  • JC Flickinger D Kondziolka LD Lunsford (1996) ArticleTitleDose and diameter relationships for facial, trigeminal, and acoustic neuropathies following acoustic neuroma radiosurgery Radiother Oncol 41 215–219 10.1016/S0167-8140(96)01831-2 Occurrence Handle1:STN:280:DyaK2s7nvFOjsg%3D%3D Occurrence Handle9027936

    CAS  PubMed  Google Scholar 

  • JC Flickinger D Kondziolka A Niranjan LD Lunsford (2001) ArticleTitleResults of acoustic neuroma radiosurgery: an analysis of 5 years experience using current methods J Neurosurg 94 1–6 Occurrence Handle1:STN:280:DC%2BD3M%2FptlektA%3D%3D Occurrence Handle11147876

    CAS  PubMed  Google Scholar 

  • JC Flickinger D Kondziolka A Niranjan A Maitz G Voynov LD Lunsford (2004) ArticleTitleAcoustic neuroma radiosurgery with marginal tumor doses of 12 to 13 Gy Int J Radiat Oncol Biol Phys 60 225–230 10.1016/j.ijrobp.2004.02.019 Occurrence Handle15337560

    PubMed  Google Scholar 

  • JC Flickinger LD Lunsford ME Linskey CM Duma D Kondziolka (1993) ArticleTitleGamma knife radiosurgery for acoustic tumors: multivariate analysis of four year results Radiother Oncol 27 91–98 10.1016/0167-8140(93)90127-T Occurrence Handle1:STN:280:DyaK3szmtFOisg%3D%3D Occurrence Handle8356233

    CAS  PubMed  Google Scholar 

  • KD Foote WA Friedman JM Buatti SL Meeks FJ Bova PS Kubilis (2001) ArticleTitleAnalysis of risk factors associated with radiosurgery for vestibular schwannoma J Neurosurg 95 440–449 Occurrence Handle1:STN:280:DC%2BD3MrhvV2jsw%3D%3D Occurrence Handle11565866

    CAS  PubMed  Google Scholar 

  • G Gardner JH Robertson (1988) ArticleTitleHearing preservation in unilateral acoustic neuroma surgery Ann Otol Rhinol Laryngol 97 55–66 Occurrence Handle1:STN:280:DyaL1c7jt1ehtQ%3D%3D Occurrence Handle3277525

    CAS  PubMed  Google Scholar 

  • A Givrè H Olivecrona (1949) ArticleTitleSurgical experiences with acoustic tumors J Neurosurg 5 396–407

    Google Scholar 

  • ME Glasscock SuffixIII JW Hays LB Minor DS Haynes VN Carrasco (1993) ArticleTitlePreservation of hearing in surgery for acoustic neuromas J Neurosurg 78 864–870 Occurrence Handle8487067

    PubMed  Google Scholar 

  • ME Glasscock SuffixIII JF Kveton CG Jackson SC Levine KX McKennan (1986) ArticleTitleA systematic approach to the surgical management of acoustic neuroma Laryngoscope 96 1088–1094 10.1288/00005537-198610000-00008 Occurrence Handle3531748

    PubMed  Google Scholar 

  • AB Grayeli S Guindi M Kalamarides HE Garem M Smail A Rey O Sterkers (2005) ArticleTitleFour-channel electromyography of the facial nerve in vestibular schwannoma surgery: sensitivity and prognostic value for short-term facial function outcome Otol Neurotol 26 114–120 10.1097/00129492-200501000-00021 Occurrence Handle15699731

    PubMed  Google Scholar 

  • K Hanabusa A Morikawa T Murata W Taki (2001) ArticleTitleAcoustic neuroma with malignant transformation. Case report J Neurosurg 95 518–521 Occurrence Handle1:STN:280:DC%2BD3MrhvV2isQ%3D%3D Occurrence Handle11565878

    CAS  PubMed  Google Scholar 

  • DG Hardy R MacFarlane D Baguley DA Moffat (1989) ArticleTitleSurgery for acoustic neurinoma. An analysis of 100 translabyrinthine operations J Neurosurg 71 799–804 Occurrence Handle1:STN:280:DyaK3c%2FmtlOmug%3D%3D Occurrence Handle2641991

    CAS  PubMed  Google Scholar 

  • SG Harner CW Beatty MJ Ebersold (1993) ArticleTitleHeadache after acoustic neuroma excision Am J Otol 14 552–555 Occurrence Handle1:STN:280:DyaK2c7islGguw%3D%3D Occurrence Handle8296857

    CAS  PubMed  Google Scholar 

  • T Hasegawa Y Kida T Kobayashi M Yoshimoto Y Mori J Yoshida (2005) ArticleTitleLong-term outcomes in patients with vestibular schwannomas treated using gamma knife surgery: 10-year follow up J Neurosurg 102 10–16 Occurrence Handle15658090

    PubMed  Google Scholar 

  • JW House DE Brackmann (1985) ArticleTitleFacial nerve grading system Otolaryngol Head Neck Surg 93 146–147 Occurrence Handle1:STN:280:DyaL2M7ovFCisg%3D%3D Occurrence Handle3921901

    CAS  PubMed  Google Scholar 

  • MF Howitz C Johansen M Tos S Charabi JH Olsen (2000) ArticleTitleIncidence of vestibular schwannoma in Denmark, 1977–1995 Am J Otol 21 690–694 Occurrence Handle1:STN:280:DC%2BD3cvktleksg%3D%3D Occurrence Handle10993460

    CAS  PubMed  Google Scholar 

  • SK Hwang DG Kim SH Paek CY Kim MK Kim JG Chi HW Jung (2002) ArticleTitleAggressive vestibular schwannomas with postoperative rapid growth: clinicopathological analysis of 15 cases Neurosurgery 51 1381–1390 10.1097/00006123-200212000-00008 Occurrence Handle12445343

    PubMed  Google Scholar 

  • HK Inoue (2005) ArticleTitleLow-dose radiosurgery for large vestibular schwannomas: long-term results of functional preservation J Neurosurg 102 IssueIDSuppl 111–113 111–113 Occurrence Handle15662791

    PubMed  Google Scholar 

  • Y Inoue K Ogawa J Kanzaki (2001) ArticleTitleQuality of life of vestibular schwannoma patients after surgery Acta Otolaryngol 121 59–61 10.1080/000164801300006281 Occurrence Handle1:STN:280:DC%2BD3M7nsFagug%3D%3D Occurrence Handle11270496

    CAS  PubMed  Google Scholar 

  • B Isaacson PR Kileny HK El-Kashlan (2005) ArticleTitlePrediction of long-term facial nerve outcomes with intraoperative nerve monitoring Otol Neurotol 26 270–273 10.1097/00129492-200503000-00025 Occurrence Handle15793418

    PubMed  Google Scholar 

  • Y Iwai K Yamanaka T Ishiguro (2003) ArticleTitleSurgery combined with radiosurgery of large acoustic neuromas Surg Neurol 59 283–289 10.1016/S0090-3019(03)00025-9 Occurrence Handle12748011

    PubMed  Google Scholar 

  • CG Jackson BM McGrew JA Forest CR Hampf ME Glasscock SuffixIII JL Brandes MB Hanson (2000) ArticleTitleComparison of postoperative headache after retrosigmoid approach: vestibular nerve section versus vestibular schwannoma resection Am J Otol 21 412–416 10.1016/S0196-0709(00)80053-8 Occurrence Handle1:STN:280:DC%2BD3czpvFKrtQ%3D%3D Occurrence Handle10821557

    CAS  PubMed  Google Scholar 

  • J Kanzaki Y Inoue K Ogawa (2001) ArticleTitleThe learning curve in post-operative hearing results in vestibular schwannoma surgery Auris Nasus Larynx 28 209–213 10.1016/S0385-8146(01)00086-4 Occurrence Handle1:STN:280:DC%2BD3MvktlSksw%3D%3D Occurrence Handle11489362

    CAS  PubMed  Google Scholar 

  • S Karjalainen J Nuutinen H Neittaanmaki A Naukkarinen R Asikainen (1984) ArticleTitleThe incidence of acoustic neuroma in and autopsy material Acta Otorhinolaryngol Belg 240 91–93 10.1007/BF00464351 Occurrence Handle1:STN:280:DyaL2c3jtV2isw%3D%3D

    CAS  Google Scholar 

  • E Kentala I Pyykko (2000) ArticleTitleVestibular schwannoma mimicking Meniere’s disease Acta Otolaryngol Suppl 543 17–19 10.1080/000164800453838

    Google Scholar 

  • E Kentala I Pyykko (2001) ArticleTitleClinical picture of vestibular schwannoma Auris Nasus Larynx 28 15–22 10.1016/S0385-8146(00)00093-6 Occurrence Handle1:STN:280:DC%2BD3M7ovVGguw%3D%3D Occurrence Handle11137358

    CAS  PubMed  Google Scholar 

  • H Koperer W Deinsberger A Jodicke DK Boker (1999) ArticleTitlePostoperative headache after the lateral suboccipital approach: craniotomy versus craniectomy Minim Invasive Neurosurg 42 175–178 Occurrence Handle1:STN:280:DC%2BD3c7ivFarsA%3D%3D Occurrence Handle10667820

    CAS  PubMed  Google Scholar 

  • O Kubo M Chernov M Izawa M Hayashi Y Muragaki T Maruyama T Hori K Takakura (2005) ArticleTitleMalignant progression of benign brain tumors after gamma knife radiosurgery: is it really caused by irradiation? Minim Invasive Neurosurg 48 334–339 10.1055/s-2005-915632 Occurrence Handle1:STN:280:DC%2BD28%2FktlKhsw%3D%3D Occurrence Handle16432782

    CAS  PubMed  Google Scholar 

  • AK Lalwani FY Butt RK Jackler LH Pitts CD Yingling (1994) ArticleTitleFacial nerve outcome after acoustic neuroma surgery: a study from the era of cranial nerve monitoring Otolaryngol Head Neck Surg 111 561–570 10.1016/S0194-5998(94)70522-4 Occurrence Handle1:STN:280:DyaK2M%2FmtVyqtw%3D%3D Occurrence Handle7970793

    CAS  PubMed  Google Scholar 

  • TH Lanman DE Brackmann WE Hitselberger B Subin (1999) ArticleTitleReport of 190 consecutive cases of large acoustic tumours (vestibular schwannomas) removed via the translabyrinthine approach J Neurosurg 90 617–623 Occurrence Handle1:STN:280:DyaK1M3gsl2ntQ%3D%3D Occurrence Handle10193604

    CAS  PubMed  Google Scholar 

  • H Levo G Blomstedt I Pyykko (2004) ArticleTitlePostural stability after vestibular schwannoma surgery Ann Otol Rhinol Laryngol 113 994–999 Occurrence Handle15633903

    PubMed  Google Scholar 

  • ME Linskey JC Flickinger LD Lunsford (1993) ArticleTitleCranial nerve length predicts the risk of delayed facial and trigeminal neuropathies after acoustic tumor stereotactic radiosurgery Int J Radiat Oncol Biol Phys 25 227–233 Occurrence Handle1:STN:280:DyaK3s7jtFGqsQ%3D%3D Occurrence Handle8420870

    CAS  PubMed  Google Scholar 

  • AH Lockwood RJ Salvi RF Burkard (2002) ArticleTitleTinnitus N Engl J Med 347 904–910 10.1056/NEJMra013395 Occurrence Handle12239260

    PubMed  Google Scholar 

  • JS Loeffler A Niemierko PH Chapman (2003) ArticleTitleSecond tumors after radiosurgery: tip of the iceberg or a bump in the road? Neurosurgery 52 1436–1440 10.1227/01.NEU.0000064809.59806.E8 Occurrence Handle12762888

    PubMed  Google Scholar 

  • JH Loge S Kaasa (1998) ArticleTitleShort form 36 (SF-36) health survey: normative data from the general Norwegian population Scand J Soc Med 26 250–258 Occurrence Handle1:STN:280:DyaK1M%2FosFKguw%3D%3D Occurrence Handle9868748

    CAS  PubMed  Google Scholar 

  • JH Loge S Kaasa MJ Hjermstad TK Kvien (1998) ArticleTitleTranslation and performance of the Norwegian SF-36 Health Survey in patients with rheumatoid arthritis. I. Data quality, scaling assumptions, reliability, and construct validity J Clin Epidemiol 51 1069–1076 10.1016/S0895-4356(98)00098-5 Occurrence Handle1:STN:280:DyaK1M%2Fjt1Sitg%3D%3D Occurrence Handle9817124

    CAS  PubMed  Google Scholar 

  • CM Luetje (2000) ArticleTitleSpontaneous involution of acoustic tumors Am J Otol 21 393–398 10.1016/S0196-0709(00)80050-2 Occurrence Handle1:STN:280:DC%2BD3czpvFKrtg%3D%3D Occurrence Handle10821554

    CAS  PubMed  Google Scholar 

  • LD Lunsford A Niranjan JC Flickinger A Maitz D Kondziolka (2005) ArticleTitleRadiosurgery of vestibular schwannomas: summary of experience in 829 cases J Neurosurg 102 IssueIDSuppl 195–199 195–199 Occurrence Handle15662809

    PubMed  Google Scholar 

  • SG Lynn CD Bauch DE Williams CW Beatty MW Mellon AL Weaver (2003) ArticleTitlePsychologic profile of tinnitus patients using the SCL-90-R and Tinnitus Handicap Inventory Otol Neurotol 24 878–881 10.1097/00129492-200311000-00009 Occurrence Handle14600467

    PubMed  Google Scholar 

  • SG Lynn CL Driscoll SG Harner CW Beatty EJ Atkinson (1999) ArticleTitleAssessment of dysequilibrium after acoustic neuroma removal Am J Otol 20 484–494 Occurrence Handle1:STN:280:DyaK1MzlvVygug%3D%3D Occurrence Handle10431891

    CAS  PubMed  Google Scholar 

  • C MacAndie JA Crowther (2004) ArticleTitleQuality of life in patients with vestibular schwannomas managed conservatively Clin Otolaryngol Allied Sci 29 215–218 10.1111/j.1365-2273.2004.00806.x Occurrence Handle1:STN:280:DC%2BD2c3ksVWrsA%3D%3D Occurrence Handle15142064

    CAS  PubMed  Google Scholar 

  • G Magliulo F Zardo R Damico S Varacalli M Forino (2000) ArticleTitleAcoustic neuroma: postoperative quality of life J Otolaryngol 29 344–347 Occurrence Handle1:STN:280:DC%2BD38%2FktlyksQ%3D%3D Occurrence Handle11770141

    CAS  PubMed  Google Scholar 

  • L Malis (1998) History LI Malis (Eds) Acoustic neuroma Elsevier New York 4–7

    Google Scholar 

  • HC Martin J Sethi D Lang G Neil-Dwyer ME Lutman L Yardley (2001) ArticleTitlePatient-assessed outcomes after excision of acoustic neuroma: postoperative symptoms and quality of life J Neurosurg 94 211–216 Occurrence Handle1:STN:280:DC%2BD3M7jsFSgsA%3D%3D Occurrence Handle11213956

    CAS  PubMed  Google Scholar 

  • C Matthies M Samii (1997) ArticleTitleManagement of 1000 vestibular schwannomas (acoustic neuromas): clinical presentation Neurosurgery 40 1–9 10.1097/00006123-199701000-00001 Occurrence Handle1:STN:280:DyaK2s7is12msg%3D%3D Occurrence Handle8971818

    CAS  PubMed  Google Scholar 

  • F Mirz B Jorgensen B Fiirgaard E Lundorf CB Pedersen (1999) ArticleTitleInvestigations into the natural history of vestibular schwannomas Clin Otolaryngol Allied Sci 24 13–18 10.1046/j.1365-2273.1999.00085.x Occurrence Handle1:STN:280:DyaK1M3ht1ektg%3D%3D Occurrence Handle10196641

    CAS  PubMed  Google Scholar 

  • F Mirz CB Pedersen B Fiirgaard E Lundorf (2000) ArticleTitleIncidence and growth pattern of vestibular schwannomas in a Danish county, 1977–1998 Acta Otolaryngol Suppl 543 30–33 10.1080/000164800453883

    Google Scholar 

  • DA Moffat DM Baguley H von Blumenthal RM Irving DG Hardy (1994) ArticleTitleSudden deafness in vestibular schwannoma J Laryngol Otol 108 116–119 Occurrence Handle1:STN:280:DyaK2c3hs1Orug%3D%3D Occurrence Handle8163910

    CAS  PubMed  Google Scholar 

  • DA Moffat DG Hardy PL Grey DM Baguley (1996) ArticleTitleThe operative learning curve and its effect on facial nerve outcome in vestibular schwannoma surgery Am J Otol 17 643–647 Occurrence Handle1:STN:280:DyaK28vjvFertg%3D%3D Occurrence Handle8841715

    CAS  PubMed  Google Scholar 

  • DA Moffat SE Jones S Mahendran R Humphriss DM Baguley (2004) ArticleTitleReferral patterns in vestibular schwannomas — 10 years on Clin Otolaryngol Allied Sci 29 515–517 10.1111/j.1365-2273.2004.00854.x Occurrence Handle1:STN:280:DC%2BD2cvmsVOgsw%3D%3D Occurrence Handle15373865

    CAS  PubMed  Google Scholar 

  • A Mohyuddin EA Vokurka DG Evans RT Ramsden A Jackson (2003) ArticleTitleIs clinical growth index a reliable predictor of tumour growth in vestibular schwannomas? Clin Otolaryngol Allied Sci 28 85–90 10.1046/j.1365-2273.2003.00670.x Occurrence Handle1:STN:280:DC%2BD3s3gsVOltA%3D%3D Occurrence Handle12680824

    CAS  PubMed  Google Scholar 

  • P Moller E Myrseth PH Pedersen JL Larsen J Krakenes G Moen (2000) ArticleTitleAcoustic neuroma-treatment modalities. Surgery, gamma-knife or observation? Acta Otolaryngol Suppl 543 34–37

    Google Scholar 

  • A Muacevic A Jess-Hempen JC Tonn B Wowra (2004) ArticleTitleResults of outpatient gamma knife radiosurgery for primary therapy of acoustic neuromas Acta Neurochir Suppl 91 75–78

    Google Scholar 

  • E Myrseth P Moller F Goplen T Wentzel-Larsen M Lund-Johansen (2006) ArticleTitleUntreated vestibular schwannoma: vertigo is a powerful predictor for health-related quality of life Neurosurgery 59 67–76 10.1227/01.NEU.0000219838.80931.6B Occurrence Handle16823302

    PubMed  Google Scholar 

  • E Myrseth P Moller PH Pedersen FS Vassbotn T Wentzel-Larsen M Lund-Johansen (2005) ArticleTitleVestibular schwannomas: clinical results and quality of life after microsurgery or gamma knife radiosurgery Neurosurgery 56 927–935 Occurrence Handle15854240

    PubMed  Google Scholar 

  • R Nader K Al Abdulhadi R Leblanc A Zeitouni (2002) ArticleTitleAcoustic neuroma: outcome study J Otolaryngol 31 207–210 Occurrence Handle1:STN:280:DC%2BD38vnvFKjsg%3D%3D Occurrence Handle12240754

    CAS  PubMed  Google Scholar 

  • BA Neff J Ting SL Dickinson DB Welling (2005) ArticleTitleFacial nerve monitoring parameters as a predictor of postoperative facial nerve outcomes after vestibular schwannoma resection Otol Neurotol 26 728–732 10.1097/01.mao.0000178137.81729.35 Occurrence Handle16015176

    PubMed  Google Scholar 

  • HK Neuhauser M von Brevern A Radtke F Lezius M Feldmann T Ziese T Lempert (2005) ArticleTitleEpidemiology of vestibular vertigo: a neurotologic survey of the general population Neurology 65 898–904 10.1212/01.wnl.0000175987.59991.3d Occurrence Handle1:STN:280:DC%2BD2Mrhtl2nug%3D%3D Occurrence Handle16186531

    CAS  PubMed  Google Scholar 

  • TP Nikolopoulos I Johnson GM O’Donoghue (1998) ArticleTitleQuality of life after acoustic neuroma surgery Laryngoscope 108 1382–1385 10.1097/00005537-199809000-00024 Occurrence Handle1:STN:280:DyaK1cvgvFWnsA%3D%3D Occurrence Handle9738762

    CAS  PubMed  Google Scholar 

  • TP Nikolopoulos GM O’Donoghue (2002) ArticleTitleAcoustic neuroma management: an evidence-based medicine approach Otol Neurotol 23 534–541 10.1097/00129492-200207000-00024 Occurrence Handle12170158

    PubMed  Google Scholar 

  • AJ Nissen A Sikand JE Welsh FS Curto J Gardi (1997) ArticleTitleA multifactorial analysis of facial nerve results in surgery for cerebellopontine angle tumors Ear Nose Throat J 76 37–40 Occurrence Handle1:STN:280:DyaK2s7ntFOlsA%3D%3D Occurrence Handle9018934

    CAS  PubMed  Google Scholar 

  • SH Nordahl T Aasen BM Dyrkorn S Eidsvik OI Molvaer (2000) ArticleTitleStatic stabilometry and repeated testing in a normal population Aviat Space Environ Med 71 889–893 Occurrence Handle1:STN:280:DC%2BD3cvkvVehtw%3D%3D Occurrence Handle11001340

    CAS  PubMed  Google Scholar 

  • G Noren (1998) ArticleTitleLong-term complications following gamma knife radiosurgery of vestibular schwannomas Stereotact Funct Neurosurg 70 IssueIDSuppl 1 65–73 Occurrence Handle9782237

    PubMed  Google Scholar 

  • K Ogawa J Kanzaki S Ogawa N Tsuchihashi Y Inoue (1991) ArticleTitleAcoustic neuromas presenting as sudden hearing loss Acta Otolaryngol Suppl 487 138–143

    Google Scholar 

  • SH Paek HT Chung SS Jeong CK Park CY Kim JE Kim DG Kim HW Jung (2005) ArticleTitleHearing preservation after gamma knife stereotactic radiosurgery of vestibular schwannoma Cancer 104 580–590 10.1002/cncr.21190 Occurrence Handle15952200

    PubMed  Google Scholar 

  • A Parving M Tos J Thomsen H Moller C Buchwald (1992) ArticleTitleSome aspects of life quality after surgery for acoustic neuroma Arch Otolaryngol Head Neck Surg 118 1061–1064 Occurrence Handle1:STN:280:DyaK3s%2FgtV2nsQ%3D%3D Occurrence Handle1389057

    CAS  PubMed  Google Scholar 

  • N Perez E Martin R Garcia-Tapia (2003) ArticleTitleDizziness: relating the severity of vertigo to the degree of handicap by measuring vestibular impairment Otolaryngol Head Neck Surg 128 372–381 10.1067/mhn.2003.102 Occurrence Handle12646840

    PubMed  Google Scholar 

  • JH Petit RS Hudes TT Chen HM Eisenberg JM Simard LS Chin (2001) ArticleTitleReduced-dose radiosurgery for vestibular schwannomas Neurosurgery 49 1299–1306 10.1097/00006123-200112000-00003 Occurrence Handle1:STN:280:DC%2BD387it1Crtg%3D%3D Occurrence Handle11846928

    CAS  PubMed  Google Scholar 

  • MS Pogodzinski SG Harner MJ Link (2004) ArticleTitlePatient choice in treatment of vestibular schwannoma Otolaryngol Head Neck Surg 130 611–616 10.1016/j.otohns.2004.02.006 Occurrence Handle15138429

    PubMed  Google Scholar 

  • BE Pollock CL Driscoll MJ Link DA Gorman CD Bauch JN Mandrekar KN Krecke CH Johnson (2006) ArticleTitlePatient outcomes after vestibular schwannoma management: a prospective comparison of microsurgical resecion and stereotactic radiosurgery Neurosurgery 59 77–85 10.1227/01.NEU.0000219217.14930.14 Occurrence Handle16823303

    PubMed  Google Scholar 

  • C Pritchard L Clapham A Davis DA Lang G Neil-Dwyer (2004) ArticleTitlePsycho-socio-economic outcomes in acoustic neuroma patients and their carers related to tumour size Clin Otolaryngol Allied Sci 29 324–330 10.1111/j.1365-2273.2004.00822.x Occurrence Handle1:STN:280:DC%2BD2czmvVaguw%3D%3D Occurrence Handle15270817

    CAS  PubMed  Google Scholar 

  • VV Raut RM Walsh AP Bath ML Bance A Guha CH Tator JA Rutka (2004) ArticleTitleConservative management of vestibular schwannomas — second review of a prospective longitudinal study Clin Otolaryngol Allied Sci 29 505–514 10.1111/j.1365-2273.2004.00852.x Occurrence Handle1:STN:280:DC%2BD2cvmsVOgsg%3D%3D Occurrence Handle15373864

    CAS  PubMed  Google Scholar 

  • J Regis W Pellet C Delsanti H Dufour PH Roche JM Thomassin M Zanaret JC Peragut (2002) ArticleTitleFunctional outcome after gamma knife surgery or microsurgery for vestibular schwannomas J Neurosurg 97 1091–1100 Occurrence Handle12450031

    PubMed  Google Scholar 

  • J Rickenmann C Jaquenod D Cerenko U Fisch (1997) ArticleTitleComparative value of facial nerve grading systems Otolaryngol Head Neck Surg 117 322–325 10.1016/S0194-5998(97)70120-7 Occurrence Handle1:STN:280:DyaK2svnvFOjuw%3D%3D Occurrence Handle9339790

    CAS  PubMed  Google Scholar 

  • PL Rigby SB Shah RK Jackler JH Chung DD Cooke (1997) ArticleTitleAcoustic neuroma surgery: outcome analysis of patient-perceived disability Am J Otol 18 427–435 Occurrence Handle1:STN:280:DyaK2sznslyrsw%3D%3D Occurrence Handle9233481

    CAS  PubMed  Google Scholar 

  • SK Robinson JR McQuaid ES Viirre LL Betzig DL Miller KA Bailey JP Harris W Perry (2003) ArticleTitleRelationship of tinnitus questionnaires to depressive symptoms, quality of well-being, and internal focus Int Tinnitus J 9 97–103 Occurrence Handle15106282

    PubMed  Google Scholar 

  • JM Rogg SH Ahn GA Tung SE Reinert G Noren (2005) ArticleTitlePrevalence of hydrocephalus in 157 patients with vestibular schwannoma Neuroradiology 47 344–351 10.1007/s00234-005-1363-y Occurrence Handle15887011

    PubMed  Google Scholar 

  • SI Rosenberg (2000) ArticleTitleNatural history of acoustic neuromas Laryngoscope 110 497–508 10.1097/00005537-200004000-00002 Occurrence Handle1:STN:280:DC%2BD3c3isFSltg%3D%3D Occurrence Handle10763994

    CAS  PubMed  Google Scholar 

  • S Rutherford A King (2005) ArticleTitleVestibular schwannoma management: what is the “best” option? Br J Neurosurg 19 309–316 10.1080/02688690500305399 Occurrence Handle1:STN:280:DC%2BD28%2FmvFWjsA%3D%3D Occurrence Handle16455536

    CAS  PubMed  Google Scholar 

  • JM Ryzenman ML Pensak JM Tew SuffixJr (2004) ArticleTitlePatient perception of comorbid conditions after acoustic neuroma management: survey results from the acoustic neuroma association Laryngoscope 114 814–820 10.1097/00005537-200405000-00005 Occurrence Handle15126736

    PubMed  Google Scholar 

  • JM Ryzenman ML Pensak JM Tew SuffixJr (2005) ArticleTitleHeadache: a quality of life analysis in a cohort of 1,657 patients undergoing acoustic neuroma surgery, results from the acoustic neuroma association Laryngoscope 115 703–711 Occurrence Handle15805885

    PubMed  Google Scholar 

  • S Sadetzki B Modan A Chetrit L Freedman (2000) ArticleTitleAn iatrogenic epidemic of benign meningioma Am J Epidemiol 151 266–272 Occurrence Handle1:STN:280:DC%2BD3c7jsVSisw%3D%3D Occurrence Handle10670551

    CAS  PubMed  Google Scholar 

  • M Samii C Matthies (1997) ArticleTitleManagement of 1000 vestibular schwannomas (acoustic neuromas): surgical management and results with an emphasis on complications and how to avoid them Neurosurgery 40 11–21 10.1097/00006123-199701000-00002 Occurrence Handle1:STN:280:DyaK2s7is12msw%3D%3D Occurrence Handle8971819

    CAS  PubMed  Google Scholar 

  • M Samii C Matthies (1997) ArticleTitleManagement of 1000 vestibular schwannomas (acoustic neuromas): hearing function in 1000 tumor resections Neurosurgery 40 248–260 10.1097/00006123-199702000-00005 Occurrence Handle1:STN:280:DyaK2s7mtVemtA%3D%3D Occurrence Handle9007856

    CAS  PubMed  Google Scholar 

  • M Samii C Matthies (1997) ArticleTitleManagement of 1000 vestibular schwannomas (acoustic neuromas): the facial nerve–preservation and restitution of function Neurosurgery 40 684–694 10.1097/00006123-199704000-00006 Occurrence Handle1:STN:280:DyaK2s3ks1KjsQ%3D%3D Occurrence Handle9092841

    CAS  PubMed  Google Scholar 

  • P Sampath MJ Holliday H Brem JK Niparko DM Long (1997) ArticleTitleFacial nerve injury in acoustic neuroma (vestibular schwannoma) surgery: etiology and prevention J Neurosurg 87 60–66 10.3171/jns.1997.87.1.0060 Occurrence Handle1:STN:280:DyaK2szksFOktg%3D%3D Occurrence Handle9202266

    CAS  PubMed  Google Scholar 

  • D Sandooram EA Grunfeld C McKinney MJ Gleeson (2004) ArticleTitleQuality of life following microsurgery, radiosurgery and conservative management for unilateral vestibular schwannoma Clin Otolaryngol Allied Sci 29 621–627 10.1111/j.1365-2273.2004.00881.x Occurrence Handle1:STN:280:DC%2BD2cnhtVenug%3D%3D Occurrence Handle15533149

    CAS  PubMed  Google Scholar 

  • M Sanna T Khrais A Russo E Piccirillo A Augurio (2004) ArticleTitleHearing preservation surgery in vestibular schwannoma: the hidden truth Ann Otol Rhinol Laryngol 113 156–163 Occurrence Handle14994774

    PubMed  Google Scholar 

  • T Santarius AR D’Sousa HM Zeitoun G Cruickshank DW Morgan (2000) ArticleTitleAudit of headache following resection of acoustic neuroma using three different techniques of suboccipital approach Rev Laryngol Otol Rhinol (Bord) 121 75–78 Occurrence Handle1:STN:280:DC%2BD3cvks1CgsQ%3D%3D

    CAS  Google Scholar 

  • JE Saunders WM Luxford KK Devgan BL Fetterman (1995) ArticleTitleSudden hearing loss in acoustic neuroma patients Otolaryngol Head Neck Surg 113 23–31 10.1016/S0194-5998(95)70140-0 Occurrence Handle1:STN:280:DyaK2Mzislenuw%3D%3D Occurrence Handle7603717

    CAS  PubMed  Google Scholar 

  • BM Schaitkin T Young SuffixIII JS Robertson V Fickel DA Wiegand (1991) ArticleTitleFacial reanimation after acoustic neuroma excision: the patient’s perspective Laryngoscope 101 889–894 10.1288/00005537-199108000-00014 Occurrence Handle1:STN:280:DyaK3MzisFyjsQ%3D%3D Occurrence Handle1865739

    CAS  PubMed  Google Scholar 

  • A Shamisa M Bance S Nag C Tator S Wong G Noren A Guha (2001) ArticleTitleGlioblastoma multiforme occurring in a patient treated with gamma knife surgery. Case report and review of the literature J Neurosurg 94 816–821 Occurrence Handle1:STN:280:DC%2BD3M3lsF2gsQ%3D%3D Occurrence Handle11354416

    CAS  PubMed  Google Scholar 

  • M Shin K Ueki H Kurita T Kirino (2002) ArticleTitleMalignant transformation of a vestibular schwannoma after gamma knife radiosurgery Lancet 360 309–310 10.1016/S0140-6736(02)09521-1 Occurrence Handle12147377

    PubMed  Google Scholar 

  • EE Smouha M Yoo K Mohr RP Davis (2005) ArticleTitleConservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm Laryngoscope 115 450–454 10.1097/00005537-200503000-00011 Occurrence Handle15744156

    PubMed  Google Scholar 

  • TJ Stewart J Liland HF Schuknecht (1975) ArticleTitleOccult schwannomas of the vestibular nerve Arch Otolaryngol 101 91–95 Occurrence Handle1:STN:280:DyaE2M7ksFGlug%3D%3D Occurrence Handle1122200

    CAS  PubMed  Google Scholar 

  • B Strasnick ME Glasscock SuffixIII D Haynes SO McMenomey LB Minor (1994) ArticleTitleThe natural history of untreated acoustic neuromas Laryngoscope 104 1115–1119 10.1288/00005537-199409000-00011 Occurrence Handle1:STN:280:DyaK2czlt1WlsQ%3D%3D Occurrence Handle8072358

    CAS  PubMed  Google Scholar 

  • A Szende NK Leidy D Revicki (2005) ArticleTitleHealth-related quality of life and other patient-reported outcomes in the European centralized drug regulatory process: a review of guidance documents and performed authorizations of medicinal products 1995 to 2003 Value Health 8 534–548 10.1111/j.1524-4733.2005.00051.x Occurrence Handle16176492

    PubMed  Google Scholar 

  • MJ Taphoorn R Stupp C Coens D Osoba R Kortmann MJ van den Bent W Mason RO Mirimanoff BG Baumert E Eisenhauer P Forsyth A Bottomley (2005) ArticleTitleHealth-related quality of life in patients with glioblastoma: a randomised controlled trial Lancet Oncol 6 937–944 10.1016/S1470-2045(05)70432-0 Occurrence Handle16321761

    PubMed  Google Scholar 

  • JC Tonn HP Schlake R Goldbrunner C Milewski J Helms K Roosen (2000) ArticleTitleAcoustic neuroma surgery as an interdisciplinary approach: a neurosurgical series of 508 patients J Neurol Neurosurg Psychiatry 69 161–166 10.1136/jnnp.69.2.161 Occurrence Handle1:STN:280:DC%2BD3cvgsFCnsA%3D%3D Occurrence Handle10896686

    CAS  PubMed  Google Scholar 

  • M Tos SE Stangerup P Caye-Thomasen T Tos J Thomsen (2004) ArticleTitleWhat is the real incidence of vestibular schwannoma? Arch Otolaryngol Head Neck Surg 130 216–220 10.1001/archotol.130.2.216 Occurrence Handle14967754

    PubMed  Google Scholar 

  • M Tos J Thomsen (1984) ArticleTitleEpidemiology of acoustic neuromas J Laryngol Otol 98 685–692 Occurrence Handle1:STN:280:DyaL2c3ms1Ghsg%3D%3D Occurrence Handle6747450

    CAS  PubMed  Google Scholar 

  • F Unger C Walch O Schrottner S Eustacchio B Sutter G Pendl (2002) ArticleTitleCranial nerve preservation after radiosurgery of vestibular schwannomas Acta Neurochir Suppl 84 77–83

    Google Scholar 

  • AT van Eck GA Horstmann (2005) ArticleTitleIncreased preservation of functional hearing after gamma knife surgery for vestibular schwannoma J Neurosurg 102 IssueIDSuppl 204–206 Occurrence Handle15662811

    PubMed  Google Scholar 

  • JP van Leeuwen JC Braspenning H Meijer CW Cremers (1996) ArticleTitleQuality of life after acoustic neuroma surgery Ann Otol Rhinol Laryngol 105 423–430 Occurrence Handle1:STN:280:DyaK283ivVahtg%3D%3D Occurrence Handle8638892

    CAS  PubMed  Google Scholar 

  • RM Walsh AP Bath ML Bance A Keller CH Tator JA Rutka (2000) ArticleTitleThe role of conservative management of vestibular schwannomas Clin Otolaryngol Allied Sci 25 28–39 10.1046/j.1365-2273.2000.00317.x Occurrence Handle1:STN:280:DC%2BD3c3isFejtg%3D%3D Occurrence Handle10764234

    CAS  PubMed  Google Scholar 

  • JE Ware SuffixJr (2000) ArticleTitleSF-36 health survey update Spine 25 3130–3139 10.1097/00007632-200012150-00008 Occurrence Handle11124729

    PubMed  Google Scholar 

  • DB Welling PW Slater RD Thomas JM McGregor JE Goodman (1999) ArticleTitleThe learning curve in vestibular schwannoma surgery Am J Otol 20 644–648 Occurrence Handle1:STN:280:DyaK1MvjtV2isQ%3D%3D Occurrence Handle10503588

    CAS  PubMed  Google Scholar 

  • DA Wiegand V Fickel (1989) ArticleTitleAcoustic neuroma — the patient’s perspective: subjective assessment of symptoms, diagnosis, therapy, and outcome in 541 patients Laryngoscope 99 179–187 10.1288/00005537-198902000-00010 Occurrence Handle1:STN:280:DyaL1M7htFOqtg%3D%3D Occurrence Handle2913427

    CAS  PubMed  Google Scholar 

  • DA Wiegand RG Ojemann V Fickel (1996) ArticleTitleSurgical treatment of acoustic neuroma (vestibular schwannoma) in the United States: report from the Acoustic Neuroma Registry Laryngoscope 106 58–66 10.1097/00005537-199601000-00012 Occurrence Handle1:STN:280:DyaK287ktVeqtw%3D%3D Occurrence Handle8544629

    CAS  PubMed  Google Scholar 

  • RJ Wiet B Mamikoglu L Odom DL Hoistad (2001) ArticleTitleLong-term results of the first 500 cases of acoustic neuroma surgery Otolaryngol Head Neck Surg 124 645–651 10.1067/mhn.2001.116020 Occurrence Handle1:STN:280:DC%2BD3MzitVGgug%3D%3D Occurrence Handle11391255

    CAS  PubMed  Google Scholar 

  • B Wowra A Muacevic A Jess-Hempen JM Hempel S Muller-Schunk JC Tonn (2005) ArticleTitleOutpatient gamma knife surgery for vestibular schwannoma: definition of the therapeutic profile based on a 10-year experience J Neurosurg 102 IssueIDSuppl 114–118 10.3171/jns.2005.102.s_supplement.0114 Occurrence Handle15662792

    PubMed  Google Scholar 

  • I Yamakami Y Uchino E Kobayashi A Yamaura (2003) ArticleTitleConservative management, gamma-knife radiosurgery, and microsurgery for acoustic neurinomas: a systematic review of outcome and risk of three therapeutic options Neurol Res 25 682–690 10.1179/016164103101202075 Occurrence Handle14579782

    PubMed  Google Scholar 

  • L Yardley B Dibb G Osborne (2003) ArticleTitleFactors associated with quality of life in Meniere’s disease Clin Otolaryngol Allied Sci 28 436–441 10.1046/j.1365-2273.2003.00740.x Occurrence Handle1:STN:280:DC%2BD3svivV2kug%3D%3D Occurrence Handle12969347

    CAS  PubMed  Google Scholar 

  • PD Yates RK Jackler B Satar LH Pitts JS Oghalai (2003) ArticleTitleIs it worthwhile to attempt hearing preservation in larger acoustic neuromas? Otol Neurotol 24 460–464 10.1097/00129492-200305000-00017 Occurrence Handle12806299

    PubMed  Google Scholar 

  • Y Yoshimoto (2005) ArticleTitleSystematic review of the natural history of vestibular schwannoma J Neurosurg 103 59–63 Occurrence Handle16121974

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neurosurgery, Institute of Surgical Science, Haukeland University Hospital, University of Bergen, Bergen, Norway

    E. Myrseth, P.-H. Pedersen & M. Lund-Johansen

  2. Department of Otorhinolaryngology, Institute of Surgical Science, Haukeland University Hospital, University of Bergen, Bergen, Norway

    P. Møller

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  1. E. Myrseth
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  3. P. Møller
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  4. M. Lund-Johansen
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Myrseth, E., Pedersen, PH., Møller, P. et al. Treatment of vestibular schwannomas. Why, when and how?. Acta Neurochir (Wien) 149, 647–660 (2007). https://doi.org/10.1007/s00701-007-1179-0

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