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A terbium(III)-functionalized zinc(II)-organic framework for fluorometric determination of phosphate

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Abstract

A terbium(III)-functionalized zinc(II)-organic framework (Tb-MOF-Zn) is shown to be a viable fluorescent probe for phosphate. The organic ligands 4,4′,4″-[((2,4,6-trimethylbenzene-1,3,5-triyl)tris(methylene))tris(oxy)]tribenzoic acid (H3L3) contains multiple carboxyl groups that can react with zinc(II) to yield tubular MOF-Zn. The MOF-Zn was further functionalized with Tb(III) to produce a lanthanide composite of type Tb-MOF-Zn which displays strong fluorescence with excitation/emission maxima at 285/544 nm. Fluorescence is quenched by phosphate because of the specific interaction with Tb(III) in Tb-MOF-Zn. The concentration of Tb-MOF-Zn, reaction time and pH value of the solution were optimized. Fluorescence drops linearly in the 0.01 to 200.0 μM phosphate concentration range, and the detection limit is 4.0 nM. The fluorescent probe was also used to prepare a microdot array on a glass slide for visual detection of phosphate under illumination with UV light.

A terbium(III) functionalized zinc(II)-organic framework was synthesized and used as fluorescent probe for determination of phosphate ions.

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Acknowledgements

This work is financially supported by the Wanjiang scholars in Anhui Province, China and the Institute of Health, Centers of Biomedical Research Excellence (NIH, COBRE, Grant number: P20 GM109024). Its contents are solely the responsibility of the authors, and do not necessarily represent the official views of the NIH.

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Authors and Affiliations

  1. Research Center for Biomedical and Health Science, Anhui Science and Technology University, Fengyang, 233100, China

    Chuan Fan, Meng Tian, Qingcai Yu, Yueyuan Mao, Wanwei Qiu & Guodong Liu

  2. Institute of Medicine and Materials Applied Technologies, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu City, Shandong Province, 273165, People’s Republic of China

    Chuan Fan, Xiaoxia Lv & Hua Wang

  3. Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND, 58102, USA

    Guodong Liu

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  1. Chuan Fan
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  2. Xiaoxia Lv
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  3. Meng Tian
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Correspondence to Hua Wang or Guodong Liu.

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Fan, C., Lv, X., Tian, M. et al. A terbium(III)-functionalized zinc(II)-organic framework for fluorometric determination of phosphate. Microchim Acta 187, 84 (2020). https://doi.org/10.1007/s00604-019-4066-5

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