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Non-enzymatic sensing of glucose and hydrogen peroxide using a glassy carbon electrode modified with a nanocomposite consisting of nanoporous copper, carbon black and nafion

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Abstract

Three-dimensional nanoporous copper (NPC) was fabricated by dealloying ribbons of an Al-Cu alloy. NPC possesses a clean metal surface and high electrical conductivity. Subsequently, a non-enzymatic electrochemical sensor was obtained by modifying a glassy carbon electrode with nanocomposites containing nanoporous copper and carbon black (NPC-CB) in a nafion matrix. The sensor, if operated at a working voltage of 0.6 V (vs. SCE) in 50 mM NaOH solution, has a linear analytical range that extends from 6.0 μM to 3.4 mM of glucose, and a 2.6 μM detection limit (at an S/N ratio of 3). It also shows good selectivity over ascorbic acid, uric acid, dopamine and carbohydrates (fructose, saccharose, and maltose). The sensor also has a rapid amperometric response to hydrogen peroxide which can be quantified with a 1.2 μM detection limit.

Nanoporous copper (NPC) was fabricated by dealloying ribbons of an Al-Cu alloy. NPC exhibits three-dimensional nanoporous structure. A nanocomposite made from NPC and carbon black in a nafion matrix shows good sensing performance toward glucose and H2O2.

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Acknowledgments

We greatly appreciate the support of the National Natural Science Foundation of China (20905010), Jiangsu Provincial Natural Science Foundation (BK20131191 and BK20140416), Qing Lan Project (SZ2014005) and Suzhou Science and Technology Project (SYN201302, SYN201515). The work is also supported by Hebei Provincial Natural Science Foundation (B2011205079).

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Authors and Affiliations

  1. School of Chemistry and Materials Engineering, Changshu Institute of Technology, Changshu, 215500, China

    Ling Mei, Pengcheng Zhang, Jiyun Chen, Dandan Chen, Ying Quan, Genhua Zhang & Rongjing Cui

  2. Department of Chemistry and materials, Hebei Normal University, Shijiazhuang, 050024, China

    Ling Mei & Ning Gu

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  1. Ling Mei
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  2. Pengcheng Zhang
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Correspondence to Rongjing Cui.

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Mei, L., Zhang, P., Chen, J. et al. Non-enzymatic sensing of glucose and hydrogen peroxide using a glassy carbon electrode modified with a nanocomposite consisting of nanoporous copper, carbon black and nafion. Microchim Acta 183, 1359–1365 (2016). https://doi.org/10.1007/s00604-016-1764-0

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  • DOI: https://doi.org/10.1007/s00604-016-1764-0

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