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Determination of triclosan and triclocarban in environmental water samples with ionic liquid/ionic liquid dispersive liquid-liquid microextraction prior to HPLC-ESI-MS/MS

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Abstract

A hydrophobic ionic liquid was finely dispersed in aqueous solution along with a hydrophilic ionic liquid. Following centrifugation, the two phases aggregate to form relatively large droplets. Based on this phenomenon, a method termed ionic liquid/ionic liquid dispersive liquid-liquid microextraction was developed. It was applied to the enrichment of triclosan (TCS) and triclocarban (TCC) from water samples prior to HPLC with electrospray tandem MS detection. The type and volume of the hydrophobic ionic liquid (the extraction solvent) and the hydrophilic ionic liquid (the disperser solvent), salt content, and extraction time were optimized. Under optimum conditions, the method gives a linear response in the concentration ranges from 0.5 to 100 μg L−1 for TCC and from 2.5 to 500 μg L−1 for TCS, respectively. The limits of detection are 0.23 and 0.35 μg L−1, and the repeatability is 5.4 and 6.4% for TCC and TCS, respectively. The method was validated with four environmental water samples, and average recoveries of spiked samples were in the range from 88% to 111%. The results indicate that the method is a promising new approach for the rapid enrichment and determination of organic pollutants.

Ionic liquids [C8MIM][PF6] and [C4MIM][BF4] were used as extractant and disperser in dispersive liquid-liquid microextraction for the enrichment and determination of triclosan and triclocarban in environmental water samples prior to HPLC-ESI-MS/MS. Experimental results indicated that it was a feasible alternative to existing methods.

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Acknowledgments

This work was financially supported by the National Natural Science Foundation of China (21077069, 21007035),Natural Science Foundation of Shandong Province (ZR2010BL029), State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences (KF2010-25).

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Authors and Affiliations

  1. Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Analysis and Test Center, Shandong Academy of Sciences, Jinan, 250014, China

    Ru-Song Zhao, Xia Wang, Jing Sun & Cong Hu

  2. Shandong Institute of Light Industry, Jinan, 250353, China

    Jing Sun & Xi-Kui Wang

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  1. Ru-Song Zhao
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  2. Xia Wang
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  3. Jing Sun
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  4. Cong Hu
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Correspondence to Ru-Song Zhao.

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Zhao, RS., Wang, X., Sun, J. et al. Determination of triclosan and triclocarban in environmental water samples with ionic liquid/ionic liquid dispersive liquid-liquid microextraction prior to HPLC-ESI-MS/MS. Microchim Acta 174, 145–151 (2011). https://doi.org/10.1007/s00604-011-0607-2

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  • DOI: https://doi.org/10.1007/s00604-011-0607-2

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