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Fast and sensitive non-enzymatic glucose concentration determination using an electroactive anionic clay-modified electrode

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Abstract

Layers of Ni-Al-NO3 layered double hydroxides were deposited on a gold electrode by electrosynthesis and applied in a low-cost non-enzymatic glucose sensor possessing high sensitivity and long-term stability. The amperometric current of the electrode is proportional to the concentration of glucose over the range of 0.0007–1.2 mM, the detection limit being 0.5 μM (at an S/N = 3). The electrode has been applied to determine glucose in glucose injection solutions, wine and urine.

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Acknowledgements

This work was supported by Natural Science Foundation of China (20801001, and 20875001), and the Science Foundation of Education Committee of Anhui Province (KJ2007B098). We also deeply appreciate the support of the foundation for doctor science research of Anhui Normal University.

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Authors and Affiliations

  1. Anhui Key Laboratory of Chemo—Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, China

    Maoguo Li, Shudong Xu, Fang Ni, Yinling Wang, Shuihong Chen & Lun Wang

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  1. Maoguo Li
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  2. Shudong Xu
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  3. Fang Ni
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  4. Yinling Wang
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  5. Shuihong Chen
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  6. Lun Wang
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Correspondence to Maoguo Li or Lun Wang.

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Li, M., Xu, S., Ni, F. et al. Fast and sensitive non-enzymatic glucose concentration determination using an electroactive anionic clay-modified electrode. Microchim Acta 166, 203–208 (2009). https://doi.org/10.1007/s00604-009-0189-4

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  • DOI: https://doi.org/10.1007/s00604-009-0189-4

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