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Catheter-associated bloodstream infection after bowel surgery in patients with inflammatory bowel disease

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Abstract

Purpose

Catheter-associated bloodstream infections (CABSIs) are a leading cause of nosocomial infections. The objectives of this study were to establish the incidence of CABSIs after bowel surgery and to identify the risk factors.

Methods

We reviewed the prospectively collected data of patients who underwent abdominal surgery with central venous catheter (CVC) insertion between March, 2006 and September, 2009. We analyzed all possible variables, including age, sex, disease, CVC duration, insertion frequency, CVC site, infliximab, corticosteroid, and immunosuppressant administration, preoperative serum albumin level, surgical wound class, and emergency surgery.

Results

A total of 1261 patients were prospectively surveyed. The underlying diseases comprised ulcerative colitis (UC; n = 428), Crohn’s disease (CD; n = 334), colorectal cancer (CA; n = 344), esophageal cancer (ESO; n = 28), gastric cancer (GAST; n = 44), and others (n = 83). The incidences of CABSI were 6.9/1000 catheter days for UC, 7.4 for CD, 4.3 for CA, 3.7 for ESO, 3.7 for GAST, and 5.1 for others. CD patients had the highest rate of CABSI. The risk factors for CABSI were CD with an odds ratio (OR) of 1.63, dirty/infected wound class (OR 3.34), and CVC insertion via the internal jugular vein (OR 9.89).

Conclusion

A high CABSI incidence was found in association with CD, especially in dirty/infected surgery. Thus, the use of CVCs should be restricted in the presence of these risk factors.

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Conflict of interest

None of the authors of this manuscript has any commercial relationships that might pose a conflict of interest in connection with the submitted article.

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Authors and Affiliations

  1. Department of Lower Gastroenterological Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan

    Motoi Uchino, Hiroki Ikeuchi, Hiroki Matsuoka, Toshihiro Bando & Naohiro Tomita

  2. Infection Control and Prevention, Hyogo College of Medicine, Nishinomiya, Japan

    Kaoru Ichiki, Kazuhiko Nakajima, Yoshiko Takahashi & Yoshio Takesue

Authors
  1. Motoi Uchino
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  2. Hiroki Ikeuchi
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  3. Hiroki Matsuoka
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  4. Toshihiro Bando
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  5. Kaoru Ichiki
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  6. Kazuhiko Nakajima
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  7. Yoshiko Takahashi
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  9. Yoshio Takesue
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Correspondence to Motoi Uchino.

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Uchino, M., Ikeuchi, H., Matsuoka, H. et al. Catheter-associated bloodstream infection after bowel surgery in patients with inflammatory bowel disease. Surg Today 44, 677–684 (2014). https://doi.org/10.1007/s00595-013-0683-5

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  • DOI: https://doi.org/10.1007/s00595-013-0683-5

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