Skip to main content

Advertisement

Log in

Analysis of the impact of the body mass index in patients with gastric carcinoma

  • Original Article
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

Background

Body mass index (BMI) has been suggested to provide clinicopathological information in tumor development and progression in patients with gastric carcinoma.

Methods

The correlation of BMI with clinicopathological features and operation-related factors was analyzed in 308 patients with gastric carcinoma who had undergone distal or total gastrectomy.

Results

There was no significant correlation of obesity, indicated by a high value of BMI, with tumor-related factors including survival, or with operation-related factors. On the other hand, more advanced tumors and worse preoperative nutritional and immunological conditions were found in patients with a lower value of BMI.

Conclusions

BMI might be a representation of the physical condition brought about by the extent of tumor progression rather than a factor influencing the factors related to gastric carcinoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Basen-Engquist K, Chang M. Obesity and cancer risk: recent review and evidence. Curr Oncol Rep. 2010; Epub ahead of print.

  2. Sinicrope FA, Foster NR, Sargent DJ, O’Connell MJ, Rankin C. Obesity is an independent prognostic variable in colon cancer survivors. Clin Cancer Res. 2010;16:1884–93.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Dawood S, Broglio K, Gonzalez-Angulo AM, Kau SW, Islam R, Hortobagyi GN, et al. Prognostic value of body mass index in locally advanced breast cancer. Clin Cancer Res. 2008;14:1718–25.

    Article  PubMed  Google Scholar 

  4. van den Brandt PA, Goldbohm RA. Nutrition in the prevention of gastrointestinal cancer. Best Pract Res Clin Gastroenterol. 2006;20:589–603.

    Article  PubMed  Google Scholar 

  5. Jung MK, Jeon SW, Cho CM, Tak WY, Kweon YO, Kim SK, et al. Hyperglycaemia, hypercholesterolaemia and the risk for developing gastric dysplasia. Dig Liver Dis. 2008;40:361–5.

    Article  CAS  PubMed  Google Scholar 

  6. Dhar DK, Kubota H, Tachibana M, Kotoh T, Tabara H, Masunaga R, et al. Body mass index determines the success of lymph node dissection and predicts the outcome of gastric carcinoma patients. Oncology. 2000;59:18–23.

    Article  CAS  PubMed  Google Scholar 

  7. Tokunaga M, Hiki N, Fukunaga T, Ohyama S, Yamaguchi T, Nakajima T. Better 5-year survival rate following curative gastrectomy in overweight patients. Ann Surg Oncol. 2009;16:3245–51.

    Article  PubMed  Google Scholar 

  8. Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma. 14th ed. Tokyo: Kanehara; 2010.

    Google Scholar 

  9. Sobin L, Gospodarowicz M, Wittekind C, International Union Against Cancer. TNM classification of malignant tumours, 7th ed. New York: Wiley-Blackwell; 2009. pp. 73–7.

  10. Gillespie EF, Sorbero ME, Hanauer DA, Sabel MS, Herrmann EJ, Weiser LJ, et al. Obesity and angiolymphatic invasion in primary breast cancer. Ann Surg Oncol. 2010;17:752–9.

    Article  PubMed  Google Scholar 

  11. Barry JD, Blackshaw GR, Edwards P, Lewis WG, Murphy P, Hodzovic I, et al. Western body mass indices need not compromise outcomes after modified D2 gastrectomy for carcinoma. Gastric Cancer. 2003;6:80–5.

    PubMed  Google Scholar 

  12. Kodera Y, Ito S, Yamamura Y, Mochizuki Y, Fujiwara M, Hibi K, et al. Obesity and outcome of distal gastrectomy with D2 lymphadenectomy for carcinoma. Hepatogastroenterol. 2004;51:1225–8.

    Google Scholar 

  13. Gretschel S, Christoph F, Bembenek A, Estevez-Schwarz L, Schneider U, Schlag PM. Body mass index does not affect systematic D2 lymph node dissection and postoperative morbidity in gastric cancer patients. Ann Surg Oncol. 2003;10:363–8.

    Article  PubMed  Google Scholar 

  14. Nozoe T, Ninomiya M, Maeda T, Matsukuma A, Nakashima H, Ezaki T. Prognostic nutritional index: a tool to predict the biological aggressiveness of gastric carcinoma. Surg Today. 2010;40:440–3.

    Article  PubMed  Google Scholar 

  15. Tsujinaka T, Sasako M, Yamamoto S, Sano T, Kurokawa Y, Nashimoto A, Gastric Cancer Surgery Study Group of Japan Clinical Oncology Group, et al. Influence of overweight on surgical complications for gastric cancer: results from a randomized control trial comparing D2 and extended para-aortic D3 lymphadenectomy (JCOG9501). Ann Surg Oncol. 2007;14:355–61.

    Article  PubMed  Google Scholar 

  16. Inagawa S, Adachi S, Oda T, Kawamoto T, Koike N, Fukao K. Effect of fat volume on postoperative complications and survival rate after D2 dissection for gastric cancer. Gastric Cancer. 2000;3:141–4.

    Article  PubMed  Google Scholar 

  17. Kodera Y, Sasako M, Yamamoto S, Sano T, Nashimoto A, Gastric Cancer Surgery Study Group of Japan Clinical Oncology Group. Identification of risk factors for the development of complications following extended and superextended lymphadenectomies for gastric cancer. Br J Surg. 2005;92:1103–9.

    Article  CAS  PubMed  Google Scholar 

  18. Oh SJ, Hyung WJ, Li C, Song J, Rha SY, Chung HC, et al. Effect of being overweight on postoperative morbidity and long-term surgical outcomes in proximal gastric carcinoma. J Gastroenterol Hepatol. 2009;24:475–9.

    Article  PubMed  Google Scholar 

  19. Ojima T, Iwahashi M, Nakamori M, Nakamura M, Naka T, Ishida K, et al. Influence of overweight on patients with gastric cancer after undergoing curative gastrectomy: an analysis of 689 consecutive cases managed by a single center. Arch Surg. 2009;144:351–8.

    Article  PubMed  Google Scholar 

  20. Nobuoka D, Gotohda N, Kato Y, Takahashi S, Konishi M, Kinoshita T. Influence of excess body weight on the surgical outcomes of total gastrectomy. Surg Today. 2011;41:928–34.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tadahiro Nozoe.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nozoe, T., Kohno, M., Iguchi, T. et al. Analysis of the impact of the body mass index in patients with gastric carcinoma. Surg Today 42, 945–949 (2012). https://doi.org/10.1007/s00595-012-0183-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-012-0183-z

Keywords

Navigation