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Leiomyosarcoma of the pancreas: Report of a case

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Abstract

Leiomyosarcoma of the pancreas is a rare neoplasm, with only 34 reported cases in the literature. We encountered a rare case of leiomyosarcoma of the pancreas, treated successfully by surgery. A 41-year-old woman was referred to our hospital for further examinations of a pancreatic tumor. Imaging studies demonstrated a solid and lobular mass, about 4 cm in diameter, in the body of pancreas. This mass had a nonuniform content and was encapsulated. We performed distal pancreatectomy and splenectomy for an assumed diagnosis of invasive ductal carcinoma. Macroscopically, a sagittal section of the operative specimen showed a well-circumscribed yellowish-white mass without any cystic changes. Immunohistological examination revealed that α-smooth muscle actin, desmin, and vimentin were positive, and the labeling index of MIB-1 was 50% or more. Based on these findings, we confirmed a diagnosis of leiomyosarcoma originating from the pancreas. During 14 months of follow-up to date, there has not been any evidence of local recurrence or distant metastasis.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan

    Hideki Izumi, Ken-Ichi Okada, Toshihide Imaizumi, Masahiro Matsuyama, Shoichi Dowaki, Kosuke Tobita & Hiroyasu Makuuchi

  2. Department of Pathology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan

    Kenichi Hirabayashi

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  1. Hideki Izumi
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  2. Ken-Ichi Okada
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  3. Toshihide Imaizumi
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  4. Kenichi Hirabayashi
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  5. Masahiro Matsuyama
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  6. Shoichi Dowaki
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  7. Kosuke Tobita
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  8. Hiroyasu Makuuchi
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Izumi, H., Okada, KI., Imaizumi, T. et al. Leiomyosarcoma of the pancreas: Report of a case. Surg Today 41, 1556–1561 (2011). https://doi.org/10.1007/s00595-010-4536-1

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  • DOI: https://doi.org/10.1007/s00595-010-4536-1

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