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Investigation of the recurrence patterns of gastric cancer following a curative resection

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Abstract

Purpose

The goal of this study was to investigate the recurrence patterns of gastric cancer and determine the predictive information of recurrence patterns of gastric cancer following a curative resection.

Methods

This study retrospectively analyzed the data of 308 gastric cancer patients who underwent a curative resection, to identify the factors associated with the recurrence patterns.

Results

One hundred and sixty-nine gastric cancer patients had recurrence following curative resection. One hundred and twenty-six patients were observed for 3 years after the operation. Locoregional recurrence formed part of the recurrence pattern in 107 patients, peritoneal dissemination was observed in 98 patients, and distant metastasis occurred in 22 patients. A multivariate analysis revealed that locoregional recurrence was only associated with the Lauren classification (P = 0.003); peritoneal dissemination was only associated with N stage (P < 0.001); and distant metastasis was only associated with the Lauren classification (P = 0.016).

Conclusions

Locoregional recurrence, peritoneal dissemination, and distant metastasis were the most common recurrence patterns of gastric cancer following a curative resection. Each recurrence pattern is associated with specific clinicopathological factors.

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Authors and Affiliations

  1. Gastric Cancer Surgery Division, Tianjin Medical University Cancer Hospital and City Key Laboratory of Tianjin Cancer Center, Tianjin, PR China

    Jingyu Deng, Han Liang, Dianchang Wang & Yong Liu

  2. Department of Pathology, Tianjin Medical University Cancer Hospital, Tianjin, PR China

    Yi Pan

  3. Institute of Lung Cancer, Tianjin Medical University General Hospital, Tianjin, PR China

    Dan Sun

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  1. Jingyu Deng
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  2. Han Liang
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  6. Yong Liu
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Deng, J., Liang, H., Wang, D. et al. Investigation of the recurrence patterns of gastric cancer following a curative resection. Surg Today 41, 210–215 (2011). https://doi.org/10.1007/s00595-009-4251-y

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  • DOI: https://doi.org/10.1007/s00595-009-4251-y

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