Skip to main content

Advertisement

Log in

Postoperative management using intensive patient-controlled epidural analgesia and early rehabilitation after an esophagectomy

  • Original Article
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

Purpose

Patient-controlled epidural analgesia (PCEA) was developed for use after surgery for thoracic esophageal cancer to relieve wound pain, introduce early rehabilitation, and provide an uneventful postoperative recovery.

Methods

This retrospective study investigated 22 patients who underwent esophageal surgery to determine the efficacy of postoperative management with PCEA. In the PCEA group (n = 12), patients had two epidural catheters inserted to cover both the thoracic and abdominal incision with a patient-controlled bolus capability.

Results

Postoperative mechanical ventilation was administered in all cases in the control group (n = 10). On the other hand, this was only necessary in two patients in the PCEA group. The amount of time the patients stayed in the intensive care unit and the hospital was significantly shorter in the PCEA group than in the control group (P < 0.001 and P < 0.01, respectively). Respiratory complications occurred in four patients in the control group, and none in the PCEA group. The mean number of supplemental analgesics administered for breakthrough pain until the 7th postoperative day was 5.5 in the control group, and 1.3 in the PCEA group (P < 0.001).

Conclusions

Early rehabilitation is facilitated with intensive PCEA, while it also improves postoperative management and reduces hospitalization after esophageal surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Sato N, Koeda K, Ikeda K, Kimura Y, Aoki K, Iwaya T, et al. Randomized study of the benefits of preoperative corticosteroid administration on the postoperative morbidity and cytokine response in patients undergoing surgery for esophageal cancer. Ann Surg 2002;236:184–190.

    Article  PubMed  Google Scholar 

  2. Morita M, Yoshida R, Ikeda K, Egashira A, Oki E, Sadanaga N, et al. Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute. Surgery 2008;143:499–508.

    Article  PubMed  Google Scholar 

  3. Watson A, Allen PR. Influence of thoracic epidural on outcome after resection for esophageal cancer. Surgery 1994;115:429–432.

    PubMed  CAS  Google Scholar 

  4. Flisberg P, Tornebrandt K, Walther B, Lundberg J. Pain relief after esophagectomy: thoracic epidural analgesia is better than parenteral opioids. J Cardiothorac Vasc Anesth 2001;15:282–287.

    Article  PubMed  CAS  Google Scholar 

  5. Ono S, Aosasa S, Mochizuki H. Effects of a protease inhibitor on reduction of surgical stress in esophagectomy. Am J Surg 1999;177:78–82.

    Article  PubMed  CAS  Google Scholar 

  6. Suda K, Kitagawa Y, Ozawa S, Miyasho T, Okamoto M, Saikawa Y, et al. Neutrophil elastase inhibitor improves postoperative clinical courses after thoracic esophagectomy. Dis Esophagus 2007;20:478–486.

    Article  PubMed  CAS  Google Scholar 

  7. Akamoto S, Okano K, Sano T, Yachida S, Izuishi K, Usuki H, et al. Neutrophil elastase inhibitor (Sivelestat) preserves antitumor immunity and reduces the inflammatory mediators associated with major surgery. Surg Today 2007;37:359–365.

    Article  PubMed  CAS  Google Scholar 

  8. Sato A, Kuwabara Y, Shinoda N, Kimura N, Ishiguro H, Fujii Y. Use of low dose dopamine, gabexate mesilate and ulinastatin reduces the water balance and pulmonary complication in thoracic esophageal patients. Dis Esophagus 2005;18:151–154.

    Article  PubMed  CAS  Google Scholar 

  9. Tuman KJ, McCarthy RJ, March RJ, DeLaria GA, Patel RV, Ivankovich AD. Effects of epidural anesthesia and analgesia on coagulation and outcome after major vascular surgery. Anesth Analg 1991;73:696–704.

    Article  PubMed  CAS  Google Scholar 

  10. Christopherson R, Beattie C, Frank SM, Norris EJ, Meinert CL, Gottlieb SO, et al. Perioperative morbidity in patients randomized to epidural or general anesthesia for lower extremity vascular surgery. Anesthesiology 1993;79:422–434.

    Article  PubMed  CAS  Google Scholar 

  11. Senagore AJ, Delaney CP, Mekhail N, Dugan A, Fazio VW. Randomized clinical trial comparing epidural anaesthesia and patient-controlled analgesia after laparoscopic segmental colectomy. Br J Surg 2003;90:1195–1199.

    Article  PubMed  CAS  Google Scholar 

  12. Luketich JD, Land SR, Sullivan EA, Alvelo-Rivera M, Ward J, Buenaventura PO, et al. Thoracic epidural versus intercostal nerve catheter plus patient-controlled analgesia: a randomized study. Ann Thorac Surg 2005;79:1845–1850.

    Article  PubMed  Google Scholar 

  13. Weber T, Matzl J, Rokitansky A, Klimscha W, Neumann K, Deusch E. Superior postoperative pain relief with thoracic epidural analgesia versus intravenous patent-controlled analgesia after minimally invasive pectus excavatum repair. J Thorac Cardiovasc Surg 2007;134:865–870.

    Article  PubMed  Google Scholar 

  14. Priestley MC, Cope L, Halliwell R, Gibson P, Chard RB, Skinner M, et al. Thoracic epidural anesthesia for cardiac surgery: the effects on tracheal intubation time and length of hospital stay. Anesth Analg 2002;94:275–282.

    Article  PubMed  CAS  Google Scholar 

  15. Weinbroum AA. Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients. Surgery 2005;138:869–876.

    Article  PubMed  Google Scholar 

  16. Mann C, Pouzeratte Y, Boccara G, Peccoux C, Vergne C, Brunat G, et al. Comparison of intravenous or epidural patient-controlled analgesia in the elderly after major abdominal surgery. Anesthesiology 2000;92:433–441.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Saeki, H., Ishimura, H., Higashi, H. et al. Postoperative management using intensive patient-controlled epidural analgesia and early rehabilitation after an esophagectomy. Surg Today 39, 476–480 (2009). https://doi.org/10.1007/s00595-008-3924-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-008-3924-2

Key words

Navigation