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Long-Term Assessments After Pancreaticoduodenectomy with Pancreatic Duct Invagination Anastomosis

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Abstract

Purpose

The purpose of this cohort was to evaluate the long-term patency of the anastomosis and the remnant pancreatic functions.

Methods

Fifty-six consecutive patients undergoing a pancreaticoduodenectomy with pancreatic duct invagination anastomosis were enrolled in this study. During the follow-up, changes in the remnant pancreatic duct size, pancreatic exocrine and endocrine functions, and nutritional status were monitored.

Results

No seriously activated pancreatic fistula, no hemorrhagic complications, no reoperations, and no in-hospital deaths were observed after surgery. A dilatation of remnant pancreatic duct was detected a total of 37 times (51%) during annual computed tomography (CT) evaluations. Pancreatic dysfunctions were observed in a considerable number of patients (exocrine 4/12, 9/14, and 8/16, endocrine 9/35, 8/27, and 4/16 at 1, 2, and 3 postoperative years, respectively). Functional declines in the remnant pancreas, duct dilatation, and a decrease in the body mass index were observed from the first year. However, these data did not progressively deteriorate thereafter, at least during the first 3 postoperative years. This study demonstrated a significant correlation between the duct dilatation and endocrine dysfunction.

Conclusion

Our pancreatic duct invagination anastomosis resulted in somewhat limited long-term outcomes, although it did prevent serious complications in the short-term.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Graduate School of Medicine, Kobe University, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan

    Yasuhiro Fujino, Ippei Matsumoto, Tetsuya Sakai, Tetsuo Ajiki, Takashi Ueda & Yoshikazu Kuroda

  2. Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan

    Yasuyuki Suzuki

Authors
  1. Yasuhiro Fujino
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  2. Yasuyuki Suzuki
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  3. Ippei Matsumoto
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  4. Tetsuya Sakai
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  5. Tetsuo Ajiki
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  6. Takashi Ueda
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  7. Yoshikazu Kuroda
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Fujino, Y., Suzuki, Y., Matsumoto, I. et al. Long-Term Assessments After Pancreaticoduodenectomy with Pancreatic Duct Invagination Anastomosis. Surg Today 37, 860–866 (2007). https://doi.org/10.1007/s00595-007-3507-7

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  • DOI: https://doi.org/10.1007/s00595-007-3507-7

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