Skip to main content
Log in

Diagnosis and management of substernal Goiter at the University of Crete

  • Review Article
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

The objective of this work was to evaluate the diagnosis and management of patients with substernal goiter (SSG) on the basis of our experience. We conducted a retrospective study of all SSGs within a series of 591 thyroidectomies performed in a tertiary referral center over a period of 14 years, analyzing epidemiological data, diagnostic criteria, and surgical results. There were 37 (6%) patients with descending goiter: 28 women (mean age 57.1 years) and 9 men (mean age 61 years). All 37 patients underwent successful surgical treatment without any major postoperative complications. A postoperative histological examination revealed a 16.6% incidence of malignancy. Despite the size and close proximity to vital organs in the mediastinum, all of the SSGs were managed successfully. A neck approach was used in all except for one patient who was operated on via sternotomy. A thorough preoperative evaluation including computed tomography scan of the neck and mediastinum, and an appropriate surgical technique ensure a positive outcome for most patients with an SSG.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Katlik MR, Grillo HC, Wang C. Substernal Goiter: analysis of 80 patients from Massachusetts General Hospital. Am J Surg 1998;149:283–7.

    Article  Google Scholar 

  2. Shahian DM. Surgical treatment of the intrathoracic goiter. In: Cady B, Rossi RL, editors. Surgery of the thyroid and parathyroid glands. 3rd ed. Philadelphia: WB Saunders; 1991. p. 215–222.

    Google Scholar 

  3. Fritts L, Thompson NW. Surgical treatment of substernal goiter. In: Freidman M, editor. Operative techniques in otolaryngology and head and neck surgery. Philadelphia: WB Saunders; 1994. p. 179–188.

    Google Scholar 

  4. Shaha AR, Newman E. Substernal goiter. J Surg Oncol 1995;60: 207–212.

    Article  PubMed  Google Scholar 

  5. McKellar DP, Verazin GT, Lim KM, Spiegel JC, Block BL. Superior vena cava syndrome and tracheal obstruction due to multi-nodular goiter. Head Neck 1994;29:72–74.

    Article  Google Scholar 

  6. Cohen JP, Cho HT. Surgery for substernal goiter. In: Freidman M, editor. Operative techniques in otolaryngology and head and neck surgery. Philadelphia: WB Saunders; 1994. p. 118–125.

    Google Scholar 

  7. Abboud B, Badaoui G, Aoun Z, Tabet G, Jebara VA. Substernal goiter: a rare cause of pulmonary hypertension and heart failure. J Laryngol Otol 2000;114(9):719–720.

    Article  PubMed  CAS  Google Scholar 

  8. Studer H, Gerber H. Clinical manifestations and management of non-toxic diffuse and nodular goiter. In: Braverman LE, Utiiger RD, editors. Werner and Ingbar’s the thyroid: a fundamental and clinical text. Philadelphia: Lippincott; 1991. p. 1114–1118.

    Google Scholar 

  9. Pulli RS, Coniglio JU. Surgical management of the substernal thyroid gland. Laryngoscope 1998;108(3):358–361.

    Article  PubMed  CAS  Google Scholar 

  10. Torre G, Borgonovo G, Amato A, Arrezo A, Ansaldo G, De Negri A, et al. Surgical management of substernal goiter: analysis of 237 patients. Am Surgeon 1995;61:826–831.

    PubMed  CAS  Google Scholar 

  11. Singh B, Lucente FE, Shaha AR. Substernal goiter: a clinical review. Am J Otolaryngol 1994;15(6):409–416.

    Article  PubMed  CAS  Google Scholar 

  12. Arisi C, Dertsiz L, Altunbas H, Demircan A, Emek K. Operative management of substernal goiter: analysis of 52 patients. Int Surg 2001;86(4):220–224.

    Google Scholar 

  13. Ozdemir A, Hasbanceci M, Hamaloglu E, Ozenc A. Surgical treatment of substernal goiter. Int Surg 2000;85(3):194–197.

    PubMed  CAS  Google Scholar 

  14. Sanders LE, Rossi RL, Shahian DM, Williamson WA. Mediastinal goiters: the need for an aggressive approach. Arch Surg 1992;127:609–613.

    PubMed  CAS  Google Scholar 

  15. Netterville JL, Coleman SC, Smith JC, Smith MM, Day TA, Burkay BB. Management of substernal goiter. Laryngoscope 1998;108(11):1611–1617.

    Article  PubMed  CAS  Google Scholar 

  16. Hedayati N, McHenry C. The clinical presentation and operative management of nodular and diffuse substernal thyroid disease. Am Surg 2002;68(3):245–251.

    PubMed  Google Scholar 

  17. Calo PG, Tatti A, Farris S, Piga G, Malloci A, Nicoloci A. Substernal goiter: personal experience. Ann Ital Chir 2005;76(4):331–335.

    PubMed  Google Scholar 

  18. Flati G, De Giacomo T, Porowska B, Flati D, Gai F, Talarino C, et al. Surgical management of substernal goiters. When is sternotomy inevitable? Clin Ter 2005;156(5):191–195.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bizakis, J., Karatzanis, A., Hajiioannou, J. et al. Diagnosis and management of substernal Goiter at the University of Crete. Surg Today 38, 99–103 (2008). https://doi.org/10.1007/s00595-006-3572-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-006-3572-3

Key words

Navigation