Abstract
In all, 1,702 unselected pregnant women from the city of La Plata were tested for gestational diabetes mellitus (GDM) and evaluated to determine GDM prevalence and risk factors. In women with GDM, we evaluated compliance with guidelines for GDM management, and perinatal complications attributable to GDM. GDM prevalence was 5.8%, and its risk factors were pre-gestational obesity, previous hyperglycaemia, age > 30 years, previous GDM (and its surrogate markers). In primi-gravida (PG) subjects, GDM was equally prevalent in the presence (4.2%) or absence (4.0%) of risk factors. In multi-gravida (MG) women, although risk factors doubled the prevalence of GDM (8.6%), in the absence of risk factors GDM prevalence was similar to that of PG women (3.9%). Half of all women with GDM received inadequate post-diagnosis obstetric control, and this induced a fourfold increase in infant perinatal complications. In conclusion, all non-hyperglycaemic 24–28-week pregnant women should be tested for GDM, although particular attention must be paid to MG women with risk factors.
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References
American Diabetes Association (2004) Position statement: gestational diabetes mellitus. Diabetes Care 27:S88–S90
Persson B, Hanson U, Lunell N-O (1997) Diabetes mellitus and pregnancy. In: Alberti KGMM, Zimmet P, DeFronzo RA, Keen H (hon) (eds) International textbook of diabetes mellitus, 2nd edn. Wiley, London, pp 1135–1149
Etchegoyen GS, de Martini ER, Parral Longobardi C et al (2001) Gestational diabetes: determination of relative importance of risk factors. Medicina (B Aires) 61:161–166
Carpenter MW (2007) Gestational diabetes, pregnancy hypertension and late vascular disease. Diabetes Care 30(Suppl 2):S246–S250
Crowther CA, Hiller GE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, for the ACHOIS Trial Group (2005) Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med 352:2477–2486
Schmitz T (2008) For universal screening of gestational diabetes mellitus. Gynecol Obstet Fertil 36:567–569
Ducarme G, Muratorio C, Luton D (2008) Against universal screening for gestational diabetes mellitus. Gynecol Obstet Fertil 36:564–566
Metzger BE, Coustan DR (1998) Summary and recommendations of the fourth international workshop-conference on gestational diabetes mellitus. The Organizing Committee. Diabetes Care 21(Suppl 2):B161–B167
Italia Diabete (2008) Italian standards for diabetes mellitus 2007: executive summary. Acta Diabetol 45:107–127
Di Cianni G, Volpe L, Casadidio I et al (2002) Universal screening and intensive metabolic management of gestational diabetes: cost-effectiveness in Italy. Acta Diabetol 39:69–73
Corcoy R, García-Patterson A, Pau E et al (2004) Is selective screening for gestational diabetes mellitus worthwhile everywhere? Acta Diabetol 41:154–157
Salzberg S, Glatstein M, Cordini R et al (1993) Estudio multicéntrico de diabetes gestacional en una población heterogénea. Rev ALAD 1:13–17
Alvariñas JH, Salzberg S (1998) Diabetes gestacional: diagnóstico, tratamiento y criterios de derivación. In: Gagliardino JJ, Fabiano A (eds) Diabetes tipo 2 no insulinodependiente: su diagnóstico, control y tratamiento, 1st edn. Sociedad Argentina de Diabetes, Buenos Aires, pp 177–186
Domenech MI, Manigot DA (2001) Diabetes gestacional (editorial). Medicina (B Aires) 61:235–238
Seghieri G, De Bellis A, Anichini R, Alviggi L, Franconi F, Breschi MC (2005) Does parity increase insulin resistance during pregnancy? Diabetes Med 22:1574–1580
Hossein-Nezhad A, Maghbooli Z, Vassigh A-R, Larijani B (2007) Prevalence of gestational diabetes mellitus and pregnancy outcomes in Iranian women. Taiwan J Obstet Gynecol 46:236–241
Mamabolo RL, Alberts M, Levitt NS, Delemarre-van de Waal HA, Steyn NP (2007) Prevalence of gestational diabetes mellitus and the effect of weight on measures of insulin secretion and insulin resistance in third-trimester pregnant rural women residing in the Central Region of Limpopo Province, South Africa. Diabetes Med 24:233–239
Dirección de Maternidad e Infancia, Ministerio de Salud y Acción Social de la Nación (1996) Diabetes y Embarazo. In: Propuesta normativa perinatal (tomo II): Atención de las patologías perinatales prevalentes. Editorial Universitaria de La Plata, La Plata, pp 43–72
Hadaegh F, Tohidi M, Harati H, Kheirandish M, Rahimi S (2005) Prevalence of gestational diabetes mellitus in southern Iran (Bandar Abbas city). Endocr Pract 11:313–318
Benchimol M, Cosson E, Faure C, Carbillon L, Attali JR, Uzan M (2006) Comparison of two routine screening strategies for gestational diabetes mellitus: the experience of Jean Verdier Hospital. Gynecol Obstet Fertil 34:107–114
Cosson E, Benchimol M, Carbillon L, Pharisien I, Paries J, Valensi P, Lormeau B, Bolie S, Uzan M, Attali JR (2006) Universal rather than selective screening for gestational diabetes mellitus may improve fetal outcomes. Diabetes Metab 32:140–146
Ezimokhai M, Joseph A, Bradley-Watson P (2006) Audit of pregnancies complicated by diabetes from one center five years apart with selective versus universal screening. Ann N Y Acad Sci 1084:132–140
Ogonowski J, Miazgowski T, Homa K, Celewicz Z, Kuczynska M (2007) Low predictive value of traditional risk factors in identifying women at risk for gestational diabetes. Acta Obstet Gynecol Scand 2:1–6
Acknowledgments
MCA is a member of Carrera de Profesional de Apoyo a la Investigación de la CICPBA. SBE is a member of Carrera del Investigador Científico del CONICET. This study was supported by Secretaría de Extensión de la Universidad Nacional de La Plata, by Ministerio de Salud de la República Argentina (Beca Carrillo-Oñativia) and by Secretaría de Salud y Medicina Social de la Municipalidad de La Plata.
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McCarthy, A.D., Curciarello, R., Castiglione, N. et al. Universal versus selective screening for the detection, control and prognosis of gestational diabetes mellitus in Argentina. Acta Diabetol 47, 97–103 (2010). https://doi.org/10.1007/s00592-009-0107-6
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DOI: https://doi.org/10.1007/s00592-009-0107-6