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The pathogenesis of idiopathic scoliosis: uncoupled neuro-osseous growth?

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Abstract.

This paper examines the following speculative hypothesis: "that in some patients with scoliosis there is disproportionate neuro-osseous growth – the longitudinal growth of the spinal cord fails to keep pace with the growth of the vertebral column and, as a consequence, the spine buckles into a scoliosis deformity". A literature review of the morphology and neurology of scoliosis does not deny the hypothesis. Several mechanisms are suggested as to why the spinal cord growth could become uncoupled from osseous growth.

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Porter, R.W. The pathogenesis of idiopathic scoliosis: uncoupled neuro-osseous growth?. Eur Spine J 10, 473–481 (2001). https://doi.org/10.1007/s005860100311

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  • DOI: https://doi.org/10.1007/s005860100311

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