Abstract
Purpose
Lumbar spine surgery is associated with significant postoperative pain. The benefits of erector spinae plane blocks (ESPBs) combined with multimodal analgesia has not been adequately studied. We evaluated the analgesic effects of bilateral ESPBs as a component of multimodal analgesia after open lumbar laminectomy.
Methods
Analgesic effects of preoperative, bilateral, ultrasound-guided ESPBs combined with standardized multimodal analgesia (n = 25) was compared with multimodal analgesia alone (n = 25) in patients undergoing one or two level open lumbar laminectomy. Other aspects of perioperative care were similar. The primary outcome measure was cumulative opioid consumption at 24 h. Secondary outcomes included opioid consumption, pain scores, and nausea and vomiting requiring antiemetics on arrival to the post-anesthesia care unit (PACU), at 24 h, 48 h, and 72 h after surgery, as well as duration of the PACU and hospital stay.
Results
Opioid requirements at 24 h were significantly lower with ESPBs (31.9 ± 12.3 mg vs. 61.2 ± 29.9 mg, oral morphine equivalents). Pain scores were significantly lower with ESPBs in the PACU and through postoperative day two. Patients who received ESPBs required fewer postoperative antiemetic therapy (n = 3, 12%) compared to those without ESPBs (n = 12, 48%). Furthermore, PACU duration was significantly shorter with ESPBs (49.7 ± 9.5 vs. 79.9 ± 24.6 min).
Conclusions
Ultrasound-guided, bilateral ESPBs, when added to an optimal multimodal analgesia technique, reduce opioid consumption and pain scores, the need for antiemetic therapy, and the duration of stay in the PACU after one or two level open lumbar laminectomy.
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Change history
28 November 2023
A Correction to this paper has been published: https://doi.org/10.1007/s00586-023-07965-1
References
Yoshihara H, Yoneoka D (2015) National trends in the surgical treatment for lumbar degenerative disc disease: United States, 2000 to 2009. Spine J 15(2):265–271. https://doi.org/10.1016/j.spinee.2014.09.026[publishedOnlineFirst:20141002]
Peene L, Le Cacheux P, Sauter AR, Joshi GP, Beloeil H (2021) Pain management after laminectomy: a systematic review and procedure-specific post-operative pain management (prospect) recommendations. Eur Spine J 30(10):2925–2935. https://doi.org/10.1007/s00586-020-06661-8[publishedOnlineFirst:20201127]
Waelkens P, Alsabbagh E, Sauter A, Joshi GP, Beloeil H (2021) Pain management after complex spine surgery: a systematic review and procedure-specific postoperative pain management recommendations. Eur J Anaesthesiol 38(9):985–994. https://doi.org/10.1097/eja.0000000000001448
Bae S, Alboog A, Esquivel KS, Abbasi A, Zhou J, Chui J (2022) Efficacy of perioperative pharmacological and regional pain interventions in adult spine surgery: a network meta-analysis and systematic review of randomised controlled trials. Br J Anaesth 128(1):98–117. https://doi.org/10.1016/j.bja.2021.08.034[publishedOnlineFirst:20211110]
Ne A, Singleton BN, Moorthy A, Buggy DJ (2022) Regional and neuraxial anaesthesia techniques for spinal surgery: a scoping review. Br J Anaesth 129(4):598–611
Phan K, Xu J, Schultz et al (2017) Full-endoscopic versus micro-endoscopic and open discectomy: a systematic review and meta-analysis of outcomes and complications. Clin Neurol Neurosurg. 154:1–12
Phan K, Mobbs RJ (2016) Minimally invasive versus open laminectomy for lumbar stenosis: a systematic review and meta-analysis. Spine 41(2):E91–E100. https://doi.org/10.1097/brs.0000000000001161
Kurd MF, Kreitz T, Schroeder G, Vaccaro AR (2017) The role of multimodal analgesia in spine surgery. J Am Acad Orthop Surg 25(4):260–268. https://doi.org/10.5435/jaaos-d-16-00049
Joshi GP, Kehlet H (2019) Postoperative pain management in the era of ERAS: an overview. Best Pract Res Clin Anaesthesiol 33(3):259–267. https://doi.org/10.1016/j.bpa.2019.07.016[publishedOnlineFirst:20190725]
Machi A, Joshi GP (2019) Interfascial plane blocks. Best Pract Res Clin Anaesthesiol 33(3):303–315. https://doi.org/10.1016/j.bpa.2019.08.001[publishedOnlineFirst:20190808]
Nielsen S, Degenhardt L, Hoban B, Gisev N (2016) A synthesis of oral morphine equivalents (OME) for opioid utilisation studies. Pharmacoepidemiol Drug Saf 25(6):733–737. https://doi.org/10.1002/pds.3945[publishedOnlineFirst:20151222]
Dewinter G, Moens P, Fieuws S, Vanaudenaerde B, Van de Velde M, Rex S (2017) Systemic lidocaine fails to improve postoperative morphine consumption, postoperative recovery and quality of life in patients undergoing posterior spinal arthrodesis. A double-blind, randomized, placebo-controlled trial. Br J Anaesth 118(4):576–85
Chin KJ, Lewis S (2019) Opioid-free analgesia for posterior spinal fusion surgery using erector spinae plane (ESP) Blocks in a multimodal anesthetic regimen. Spine Phila Pa 44(6):E379-e83
Singh S, Choudhary NK, Lalin D, Verma VK (2020) Bilateral ultrasound-guided erector spinae plane block for postoperative analgesia in lumbar spine surgery: a randomized control trial. J Neurosurg Anesthesiol 32(4):330–334. https://doi.org/10.1097/ana.0000000000000603
Finnerty D, NEAhmedPoyntonButlerBuggy AMAJSDJ (2021) A randomised trial of bilateral erector spinae plane block vs no block for thoracolumbar decompressive spinal surgery. Anaesthesia 76(11):1499–503
Goel VK, Chandramohan M, Murugan C et al (2021) Clinical efficacy of ultrasound guided bilateral erector spinae block for single-level lumbar fusion surgery: a prospective, randomized, case-control study. Spine J 21(11):1873–1880. https://doi.org/10.1016/j.spinee.2021.06.015[publishedOnlineFirst:20210623]
Soffin EM, Okano I, Oezel L et al (2022) Impact of ultrasound-guided erector spinae plane block on outcomes after lumbar spinal fusion: a retrospective propensity score matched study of 242 patients. Reg Anesth Pain Med 47(2):79–86. https://doi.org/10.1136/rapm-2021-103199[publishedOnlineFirst:20211117]
Stark PA, Myles PS, Burke JA (2013) Development and psychometric evaluation of a postoperative quality of recovery score: the QoR-15. Anesthesiology 118(6):1332–1340. https://doi.org/10.1097/ALN.0b013e318289b84b
Myles PS, Myles DB, Galagher W et al (2017) Measuring acute postoperative pain using the visual analog scale: the minimal clinically important difference and patient acceptable symptom state. Br J Anaesth 118(3):424–429. https://doi.org/10.1093/bja/aew466
Rajan N, Joshi GP (2021) Management of postoperative nausea and vomiting in adults: current controversies. Curr Opin Anaesthesiol 34(6):695–702. https://doi.org/10.1097/aco.0000000000001063
Dietz N, Sharma M, Adams S et al (2019) Enhanced recovery after surgery (ERAS) for spine surgery: a systematic review. World Neurosurg 130:415–426. https://doi.org/10.1016/j.wneu.2019.06.181[publishedOnlineFirst:20190702]
Rollins KE, Lobo DN, Joshi GP (2021) Enhanced recovery after surgery: current status and future progress. Best Pract Res Clin Anaesthesiol 35(4):479–489. https://doi.org/10.1016/j.bpa.2020.10.001[publishedOnlineFirst:20201010]
Elsharydah A, Duncan KL, Rosero EB, Minhajuddin A, Somasundaram A, Joshi GP (2021) Readmission rate after 2-level lumbar decompression: a propensity-matched cohort study comparing inpatient and outpatient settings. Clin Spine Surg 34(1):E1-e6. https://doi.org/10.1097/bsd.0000000000000990
Cha EDK, Lynch CP, Hrynewycz NM et al (2022) Spine surgery complications in the ambulatory surgical center setting: systematic review. Clin Spine Surg 35(3):118–126. https://doi.org/10.1097/bsd.0000000000001225
Joshi GP (2021) Putting patients first: ambulatory surgery facilitates patient-centered care. Curr Opin Anaesthesiol 34(6):667–671. https://doi.org/10.1097/aco.0000000000001070
Joshi GP (2020) Enhanced recovery pathways for ambulatory surgery. Curr Opin Anaesthesiol 33(6):711–717. https://doi.org/10.1097/aco.0000000000000923
Joshi GP (2021) General anesthetic techniques for enhanced recovery after surgery: Current controversies. Best Pract Res Clin Anaesthesiol 35(4):531–541. https://doi.org/10.1016/j.bpa.2020.08.009[publishedOnlineFirst:20200814]
Alexander JC, Patel B, Joshi GP (2019) Perioperative use of opioids: current controversies and concerns. Best Pract Res Clin Anaesthesiol 33(3):341–351. https://doi.org/10.1016/j.bpa.2019.07.009[publishedOnlineFirst:20190717]
Shanthanna H, Ladha KS, Kehlet H, Joshi GP (2021) Perioperative opioid administration. Anesthesiology 134(4):645–659. https://doi.org/10.1097/aln.0000000000003572
Joshi GP, Vetter TR (2020) Unanticipated hospital admission after ambulatory surgery: the devil is in the details. Anesth Analg 131(2):494–496. https://doi.org/10.1213/ane.0000000000004947
Joshi GP, Vetter TR (2021) Causes of delays in the ambulatory surgery center setting: a keen grasp of the obvious? Anesth Analg 133(6):1402–1405. https://doi.org/10.1213/ane.0000000000005445
Raft J, Millet F, Meistelman C (2015) Example of cost calculations for an operating room and a post-anaesthesia care unit. Anaesth Crit Care Pain Med 34(4):211–215. https://doi.org/10.1016/j.accpm.2014.11.002[publishedOnlineFirst:20150527]
Tulgar S, Ahiskalioglu A, De Cassai A, Gurkan Y (2019) Efficacy of bilateral erector spinae plane block in the management of pain: current insights. J Pain Res 12:2597–2613. https://doi.org/10.2147/jpr.S182128[publishedOnlineFirst:20190827]
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GPJ has received honoraria from Baxter Pharmaceuticals. The other authors have no conflict of interest to declare.
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Stewart, J.W., Dickson, D., Van Hal, M. et al. Ultrasound-guided erector spinae plane blocks for pain management after open lumbar laminectomy. Eur Spine J 33, 949–955 (2024). https://doi.org/10.1007/s00586-023-07881-4
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DOI: https://doi.org/10.1007/s00586-023-07881-4