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Long-term recurrence rates after the removal of spinal meningiomas in relation to Simpson grades

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Abstract

Purpose

Simpson grade II removal (coagulation of the dural attachment after gross total removal) of spinal meningioma is considered an acceptable alternative, but increased recurrence after more than 10 years has been reported. More attention must be paid to the long-term surgical outcomes after Simpson grade II removal.

Methods

A retrospective review was performed for 20 patients (M:F = 5:15; age, 59 ± 9 years) with Simpson grade II removal (mean follow-up period, 12.9 years; range 10.0–17.5). Magnetic resonance (MR) imaging was conducted in 17 patients at 88 ± 52 months (range 12–157). During the same period, Simpson grade I removal (removal of the dural origin) was performed in 21 patients (follow-up, 89 ± 87 months; range 9–316). Radiological recurrence was defined as a visible tumor on a follow-up MR image, and clinical tumor recurrence was defined as the recurrence of symptoms.

Results

At the final follow-up, neurological symptoms had improved in 16/20 patients and remained stable in 4/20. A recurrent tumor was detected in one patient due to increased back pain at 92 months postoperative, but the symptom was stable without surgery until the last follow-up (124 months). The radiological and clinical recurrence-free survival periods were 150 ± 7 months (95 % CI 136–163) and 204 ± 6 months (95 % CI 193–215), respectively. There was no recurrence after Simpson grade I removal, whereas neurological deterioration occurred in two patients after surgery.

Conclusions

Simpson grade II removal may be an alternative option if the risk of complications with Simpson grade I removal is expected to be high.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Seoul National University Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, 03080, South Korea

    Chi Heon Kim & Chun Kee Chung

  2. Department of Neurosurgery, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul, 110-744, South Korea

    Chi Heon Kim, Chun Kee Chung, Tae-Ahn Jahng, Seung-Jae Hyun, Ki-Jeong Kim & Hyun-Jib Kim

  3. Neuroscience Research Institute, Seoul National University Medical Research Center, Seoul, South Korea

    Chi Heon Kim, Chun Kee Chung, Tae-Ahn Jahng, Seung-Jae Hyun, Ki-Jeong Kim & Hyun-Jib Kim

  4. Clinical Research Institute, Seoul National University Hospital, Seoul, South Korea

    Chi Heon Kim, Chun Kee Chung, Tae-Ahn Jahng, Seung-Jae Hyun, Ki-Jeong Kim & Hyun-Jib Kim

  5. Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, South Korea

    Chun Kee Chung

  6. Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Sun-Ho Lee, Eun-Sang Kim & Whan Eoh

  7. Department of Neurosurgery, Seoul National University Bundang Hospital, Sung-Nam, Kyung-gi, South Korea

    Tae-Ahn Jahng, Seung-Jae Hyun, Ki-Jeong Kim & Hyun-Jib Kim

  8. Department of Neurosurgery, The Armed Forces Capital Hospital, Sung-Nam, Kyung-gi, South Korea

    Sang Hoon Yoon

  9. Department of Neurosurgery, Kyungpook National University Hospital, Taegu, Kyungpook, South Korea

    Kyoung-Tae Kim & Joo-Kyung Sung

  10. Medical Research Collaborating Center, Seoul National University College of Medicine, Seoul, South Korea

    Yunhee Choi

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  1. Chi Heon Kim
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  2. Chun Kee Chung
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  3. Sun-Ho Lee
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Corresponding author

Correspondence to Chun Kee Chung.

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Disclosure and funding source

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2010-0028631). The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. This study was approved by the institutional review board of the Seoul National University Hospital Clinical Research Institute (IRB No. 1306-106-500).

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On behalf of the Korea Spinal Oncology Research Group.

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Kim, C.H., Chung, C.K., Lee, SH. et al. Long-term recurrence rates after the removal of spinal meningiomas in relation to Simpson grades. Eur Spine J 25, 4025–4032 (2016). https://doi.org/10.1007/s00586-015-4306-2

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  • DOI: https://doi.org/10.1007/s00586-015-4306-2

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