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Spontaneous spinal epidural hematoma as the initial presentation of leukemia

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Abstract

We present a case of a 55-year-old male with progressive neurological deficits that appeared dramatically. MRI detected a spinal epidural hematoma at the cervicothoracic junction and blood tests showed leukocytosis, mild anemia, and thrombocytosis. Spontaneous spinal epidural hematoma (SSEH) as the initial presentation of leukemia was diagnosed. Urgent posterior decompression was performed after 28 h from acute onset of backache, and the patient experienced remarkable improvement in neurological findings.

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References

  1. Aoyagi N, Kojima K, Kasai H (2003) Review of spinal epidural cavernous hemangioma. Neurol Med Chir (Tokyo) 43:471–475. doi:10.2176/nmc.43.471 discussion 476

    Article  Google Scholar 

  2. Banerjee R, Stanley J, Palumbo M (2004) Spinal epidural hematoma induced by leukemia. Orthopedics 27:864–866

    PubMed  Google Scholar 

  3. Bauduceau O, De Revel T, Fogelman J, Amadou S, Souleau B, Nedellec G (2003) Spontaneous hematoma of the iliac psoas muscle in chronic myeloid leukemia. A case report. Ann Med Interne (Paris) 154:183–186

    Google Scholar 

  4. Boukobza M, Guichard JP, Boissonet M, George B, Reizine D, Gelbert F, Merland JJ (1994) Spinal epidural haematoma: report of 11 cases and review of the literature. Neuroradiology 36:456–459. doi:10.1007/BF00593683

    Article  PubMed  CAS  Google Scholar 

  5. Braun P, Kazmi K, Nogues-Melendez P, Mas-Estelles F, Aparici-Robles F (2007) MRI findings in spinal subdural and epidural hematomas. Eur J Radiol 64:119–125. doi:10.1016/j.ejrad.2007.02.014

    Article  PubMed  Google Scholar 

  6. Clarke DB, Bertrand G, Tampieri D (1992) Spontaneous spinal epidural hematoma causing paraplegia: resolution and recovery without surgical decompression. Neurosurgery 30:108–111. doi:10.1097/00006123-199201000-00019

    Article  PubMed  CAS  Google Scholar 

  7. Groen RJ, Ponssen H (1990) The spontaneous spinal epidural hematoma. A study of the etiology. J Neurol Sci 98:121–138. doi:10.1016/0022-510X(90)90253-J

    Article  PubMed  CAS  Google Scholar 

  8. Hayem G, Deutsch E, Roux S, Palazzo E, Grossin M, Meyer O (1998) Spontaneous spinal epidural hematoma with spinal cord compression complicating plasma cell myeloma. A case report. Spine 23:2432–2435. doi:10.1097/00007632-199811150-00015

    Article  PubMed  CAS  Google Scholar 

  9. Hejazi N, Thaper PY, Hassler W (1998) Nine cases of nontraumatic spinal epidural hematoma. Neurol Med Chir (Tokyo) 38:718–723. doi:10.2176/nmc.38.718 discussion 723–4

    Article  CAS  Google Scholar 

  10. Holtas S, Heiling M, Lonntoft M (1996) Spontaneous spinal epidural hematoma: findings at MR imaging and clinical correlation. Radiology 199:409–413

    PubMed  CAS  Google Scholar 

  11. Kuker W, Schaade L, Ritter K, Nacimiento W (1999) MRI follow-up of herpes simplex virus (type 1) radiculomyelitis. Neurology 52:1102–1103

    PubMed  CAS  Google Scholar 

  12. Kuo YC, Wang HC, Chu KA, Lu JY (2000) Chronic myeloid leukemia initially presenting with spontaneous mediastinal hematoma and hemothorax. Zhonghua Yi Xue Za Zhi (Taipei) 63:170–174

    CAS  Google Scholar 

  13. Lawton MT, Porter RW, Heiserman JE, Jacobowitz R, Sonntag VK, Dickman CA (1995) Surgical management of spinal epidural hematoma: relationship between surgical timing and neurological outcome. J Neurosurg 83:1–7

    Article  PubMed  CAS  Google Scholar 

  14. Liao CC, Lee ST, Hsu WC, Chen LR, Lui TN, Lee SC (2004) Experience in the surgical management of spontaneous spinal epidural hematoma. J Neurosurg 100:38–45

    PubMed  Google Scholar 

  15. Matsumura A, Namikawa T, Hashimoto R, Okamoto T, Yanagida I, Hoshi M, Noguchi K, Takami M (2008) Clinical management for spontaneous spinal epidural hematoma: diagnosis and treatment. Spine J 8:534–537. doi:10.1016/j.spinee.2007.01.009

    Article  PubMed  Google Scholar 

  16. Mattle H, Sieb JP, Rohner M, Mumenthaler M (1987) Nontraumatic spinal epidural and subdural hematomas. Neurology 37:1351–1356

    PubMed  CAS  Google Scholar 

  17. Morrison VA (1994) Chronic leukemias. CA Cancer J Clin 44:353–377. doi:10.3322/canjclin.44.6.353

    Article  PubMed  CAS  Google Scholar 

  18. Singer MB, Atlas SW, Drayer BP (1998) Subarachnoid space disease: diagnosis with fluid-attenuated inversion-recovery MR imaging and comparison with gadolinium-enhanced spin-echo MR imaging–blinded reader study. Radiology 208:417–422

    PubMed  CAS  Google Scholar 

  19. Wehmeier A, Daum I, Jamin H, Schneider W (1991) Incidence and clinical risk factors for bleeding and thrombotic complications in myeloproliferative disorders. A retrospective analysis of 260 patients. Ann Hematol 63:101–106. doi:10.1007/BF01707281

    Article  PubMed  CAS  Google Scholar 

  20. Yong A, Goldman JM (2000) Chronic myeloid leukemia, 2nd edn. Churchill Livingstone, New York

    Google Scholar 

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None of the authors has any potential conflict of interest.

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Authors and Affiliations

  1. Department of Orthopaedics, Saisei Hospital, 800-1 Kashiwai-cho, Hanamigawa-ku, Chiba, 262-8506, Japan

    Hidetoshi Nojiri, Sungdo Kim & Soichi Uta

  2. Department of Orthopaedics, Juntendo Tokyo Koto Geriatric Medical Center, Juntendo University, Tokyo, Japan

    Takaaki Tsuji

Authors
  1. Hidetoshi Nojiri
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  2. Sungdo Kim
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  3. Takaaki Tsuji
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  4. Soichi Uta
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Correspondence to Hidetoshi Nojiri.

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Nojiri, H., Kim, S., Tsuji, T. et al. Spontaneous spinal epidural hematoma as the initial presentation of leukemia. Eur Spine J 18 (Suppl 2), 220–223 (2009). https://doi.org/10.1007/s00586-008-0863-y

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  • DOI: https://doi.org/10.1007/s00586-008-0863-y

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