Skip to main content
Log in

Spondylitis following vertebroplasty: a case report

  • Case Report
  • Published:
European Spine Journal Aims and scope Submit manuscript

Abstract

Purpose: Spondylitis is a rare complication of vertebroplasty with only one case report having been published to date. We report a further case of spondylitis after vertebroplasty that was managed successfully with conservative therapy. Methods: The clinical course of a 55-year-old patient with secondary osteoporosis due to liver cirrhosis from alcohol abuse is reported, in whom percutaneous vertebroplasty of three fractured vertebral bodies (L3–L5) was complicated by spondylitis at these levels. Results: Spondylitis of L3–L5 with paravertebral abscess formation and progressive collapse of L5 was detected by magnetic resonance imaging (MRI). Treatment consisted of percutaneous aspiration of the paravertebral abscess and antibiotic therapy. No bacteria was identified despite cultures have been taken before antibiotic treatment. The patient was treated with intravenous ciprofloxacin and consecutive clindamycin for a total of 3 months. One year after the infection the MRI signs of spondylitis have resolved without further collapse of L5. Painlevels have improved significantly, allowing the patient to return to work, but are still higher than immediately after vertebroplasty. Conclusion: Spondylitis is a rare complication of vertebroplasty. In the presented case a satisfactory result could be achieved through conservative antibiotic therapy and restriction of movement.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Al-Assir I, Perez-Higueras A, Florensa J, Munoz A, Cuesta E (2000) Percutaneous vertebroplasty: a special syringe for cement injection. Am J Neuroradiol 21:159–161

    CAS  PubMed  Google Scholar 

  2. Barr JD, Barr MS, Lemley TJ, McCann RM (2000) Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine 8:923–928

    Article  Google Scholar 

  3. Berlemann U, Heini PF (2002) Perkutane Zementierungstechniken zur Behandlung osteoporotischer Wirbelkörpersinterungen. Unfallchirurg 105:2–8

    Article  CAS  PubMed  Google Scholar 

  4. Bernhard J, Heini PF, Villinger PM (2003) Asymptomatic diffuse pulmonary embolism caused by acrylic cement: an unusual complication of percutaneous vertebroplasty. Ann Rheum Dis 62:85–86

    Article  CAS  PubMed  Google Scholar 

  5. Bong-Jin L, Sung-Rak L, Tae-Yeul Y (2002) Paraplegia as a complication of percutaneous vertebroplasty with polymethylmethacrylate. Spine 19:419–422

    Google Scholar 

  6. Chen HL, Wong CS, Ho ST, Chang FL, Hsu CH, Wu CT (2002) A lethal pulmonary embolism during percutaneous vertebroplasty. Anesth Analg 95:1060–1062

    Article  PubMed  Google Scholar 

  7. Cortet B, Cotton A, Boutry N, Flipo RM, Duquesnoy B, Chastanet P, Delcambre B (1999) Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study. J Rheumatol 26:2222–2228

    CAS  PubMed  Google Scholar 

  8. Cotton A, Dewatre F, Cortet B, Assaker R, Leblond D, Duquesnoy B, Chastanet P, Clarisse J (1996) Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up. Radiology 200:525–530

    CAS  PubMed  Google Scholar 

  9. Debussche-Depriester C, Deramond H, Fardellone P, Heleg A, Sebert JL, Cartz L, Galibert P (1991) Percutaneous vertebroplasty with acrylic cement in the treatment of osteoporotic vertebral crush fracture syndrome. Neuroradiology 33(Suppl):149–152

    Article  PubMed  Google Scholar 

  10. Garfin SR, Yuan HA, Reiley MA (2001) New Technologies in Spine: Kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine 14:1511–1515

    Article  Google Scholar 

  11. Gelb H, Schumacher HR, Cuckler J, Baker DG (1994) In vivo inflammatory response to polymethylmethacrylate particulate debris: effect of size, morphology and surface area. J Orthop Res 12:83–92

    Article  CAS  PubMed  Google Scholar 

  12. Hardouin P, Fayada P, Leclet H, Chopin D (2002) Review: kyphoplasty. Joint Bone Spine 69:256–261

    Article  PubMed  Google Scholar 

  13. Harrington KD (2001) Major neurological complications following percutaneous vertebroplasty with polymethylmethacrylate. A case report. J Bone Joint Surg 7:1070–1073

    Google Scholar 

  14. Heini PF, Wälchli B, Berlemann U (2000) Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. Eur Spine J 9:445–450

    Article  CAS  PubMed  Google Scholar 

  15. Jang JS, Lee SH, Jung SK (2002) Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty. A report of three cases. Spine 19:416–418

    Article  Google Scholar 

  16. Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE (1997) Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. Am J Neuroradiol 18:1897–1904

    CAS  PubMed  Google Scholar 

  17. Konno S, Olmarker K, Byröd G, Nordborg C, Strömqvist B, Rydevik B (1994) Acute thermal nerve root injury. Eur Spine J 3:299–302

    CAS  PubMed  Google Scholar 

  18. Kraus GJ, Achatz W, Görzer HG (2003) Becken- und Beinvenenthrombose als Komplikation der perkutanen Vertebroplastie. Fortschr Röntgenstr 175:565–566

    Article  Google Scholar 

  19. Lieberman IH, Dudeney S, Reinhardt MK, Bell G (2001) Initial outcome and efficacy of ”Kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine 14:1631–1638

    Article  Google Scholar 

  20. Lin JT, Lane JM (2002) Nonmedical management of osteoporosis. Rheumatology 14:441–446

    Google Scholar 

  21. Martin JB, Jean B, Sugiu K, San Millan Ruiz D, Piotin M, Murphy K, Rüfenacht B, Muster M, Rüfenacht DA (1999) Vertebroplasty: clinical experience and follow-up results. Bone 2 (Suppl):11–15

    Article  Google Scholar 

  22. Padovani B, Kasriel O, Brunner P, Peretti-Viton P (1999) Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty. Am J Neuroradiol 20:375–377

    CAS  PubMed  Google Scholar 

  23. Perez-Higueras A, Alvarez L, Rossi RE, Quinones D, Al-Assir I (2002) Percutaneous vertebroplasty: long-term clinical and radiological outcome. Neuroradiology 44:950–954

    Article  CAS  PubMed  Google Scholar 

  24. Perrin C, Jullien V, Padovani B, Blaive B (1999) Une vertebroplastie percutanee compliquee d’une embolie pulmonaire de ciment acrylique. Rev Mal Respir 16:215–217

    CAS  PubMed  Google Scholar 

  25. Prymka M, Pühler T, Hirt S, Ulrich HW (2003) Extrakorporaler Zementabfluss mit Füllung des extraduralen Venenplexus bis in die V. cava nach Vertebroplastie. Unfallchirurg 106:860–864

    Article  CAS  PubMed  Google Scholar 

  26. Ratliff J, Nguyen T, Heiss J (2001) Root and spinal cord compression from methylmethacrylate vertebroplasty. Spine 13:300–302

    Article  Google Scholar 

  27. Ryu KS, Park CK, Kim MC, Kang JK (2002) Dose-dependent epidural leakage of polymethylmethacrylate after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures. J Neurosurg (Spine1) 96:56–61

    Google Scholar 

  28. Scroop R, Eskridge J, Britz GW (2002) paradoxical cerebral arterial embolization of cement during intraoperative vertebroplasty: case report. AJNR 23:868–870

    PubMed  Google Scholar 

  29. Szpalski M, Gunzburg R, Deramond H (2003) Percutaneous injection of cortoss synthetic bone void filler in the repair of fractures in the vertebral body. In: Szpalski M, Gunzburg R, Deramond H (eds) Vertebral osteoporotic compression fractures. Lipincott Williams Wilkins, Philadelphia, pp 171–178

    Google Scholar 

  30. Tozzi P, Abdelmoumene Y, Corno AF, Gersbach PA, Hoogewoud HM, von Segesser LK (2002) Management of pulmonary embolism during acrylic vertebroplasty. Ann Thorac Surg 74:1706–1708

    PubMed  Google Scholar 

  31. Uppin AA, Hirsch JA, Centenera LV, Pfiefer BA, Pazianos AG, Chol IS (2003) Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology 226:119–124

    Google Scholar 

  32. Weill A, Chiras J, Simon JM, Rose M, Sola-Martinez T, Enkaoua E (1996) Spinal metastases: Indications for and results of percutaneous injection of acrylic surgical cement. Radiology 199:241–247

    Google Scholar 

  33. Wenger M, Markwalder TM (1999) Surgically controlled, transpedicular methyl methacrylate vertebroplasty with fluoroskopic guidance. Acta Neurochir 141:625–631

    Article  CAS  Google Scholar 

  34. Wong W, Reiley MA, Garfin S (2000) Vertebroplasty/Kyphoplasty. J Women’s Imaging 3:117–124

    Google Scholar 

  35. Yu SW, Chen WJ, Lin WC, Chen YJ, Tu YK (2004) Serious pyogenic spondylitis following vertebroplasty—a case report. Spine 29:209–211

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Katharina E. Schmid.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schmid, K.E., Boszczyk, B.M., Bierschneider, M. et al. Spondylitis following vertebroplasty: a case report. Eur Spine J 14, 895–899 (2005). https://doi.org/10.1007/s00586-005-0905-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00586-005-0905-7

Keywords

Navigation