Abstract
This study was designed to evaluate the impact of racing on serum concentrations of haptoglobin (Hp) and serum amyloid A (SAA) acute-phase proteins (APPs) in racing camels (Camelus dromedarius). Blood samples were collected 24 h prior to a 5-km race (T0) and within 2 h of completion of the race (T1). The white blood cell counts (WBCCs) were determined in EDTA blood samples. In the serum samples, the concentrations of cortisol, lactate, Hp, and SAA were determined within 2 weeks of sampling. Compared to pre-race values, the post-race WBCCs did not differ significantly. The mean serum cortisol concentrations increased significantly post-race; however, the mean serum lactate concentrations decreased significantly following the race. The serum concentrations of Hp and SAA APPs increased significantly post-race. The elevations of Hp and SAA suggest that an acute-phase reaction occurred in the camels after the race, thus shedding light on the impact of racing on the release of APPs.
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References
Alsemgeest SPM, Lambooy IE, Wierenga HK, Dieleman SJ, Meerkerk B, van Ederen AM, Niewold TA (1995) Influence of physical stress on the plasma concentrations of serum amyloid A (SAA) and haptoglobin (Hp) in calves. Vet Q 17:9–12
Baghshani H, Nazifi S, Saeb M, Saeb S (2010) Influence of road transportation on plasma concentrations of acute phase proteins, including fibrinogen, haptoglobin, serum amyloid A, and ceruloplasmin, in dromedary camels (Camelus dromedarius). Comp Clin Pathol 19:193–198
Bauer NB, Er E, Moritz A (2012) Effect of submaximal aerobic exercise on platelet function, platelet activation, and secondary and tertiary hemostasis in dogs. Am J Vet Res 73:125–133
Ceron JJ, Eckersall PD, Martinez-Subiela S (2005) Acute phase proteins in dogs and cats; current knowledge and future perspectives. Vet Clin Pathol 34:85–99
Cywinska A, Szarska E, Górecka R, Witkowski L, Hecold M, Bereznowski A, Schollenberger A, Winnicka A (2012) Acute phase protein concentrations after limited distance and long distance endurance rides in horses. Res Vet Sci 93:1402–1406
Eckersall PD (2000) Acute phase proteins as markers of infection and inflammation: monitoring animal health, animal welfare and food safety. Ir Vet J 53:307–311
Eckersall PD, Bell R (2010) Acute phase proteins: biomarkers of infection and inflammation in veterinary medicine. Vet J 185:23–27
Gronlund U, Hulten C, Eckersall PD, Hogarth C, Waller KP (2003) Haptoglobin and serum amyloid A in milk and serum during acute and chronic experimentally induced Staphylococcus aureus mastitis. J Dairy Res 70:379–386
Mastorakos G, Pavlatou M, Diamanti-Kandarakis E, Chrousos GP (2005) Exercise and the stress system. Hormones (Athens) 4:73–89
Murata H (2007) Stress and acute phase protein response: an inconspicuous but essential linkage. Vet J 173:473–474
Murata H, Shimada N, Yoshioka M (2004) Current research on acute phase proteins in veterinary diagnosis: an overview. Vet J 168:24–40
Nazifi S, Oryan AM, Ansari-Lari M, Tabandeh MR, Mohammadalipour A, Gowharnia M (2012) Evaluation of sialic acids and their correlation with acute-phase proteins (haptoglobin and serum amyloid A) in clinically healthy Iranian camels (Camelus dromedarius). Comp Clin Pathol 21:383–387
Petersen HH, Nielsen JP, Heegaard PMH (2004) Application of acute phase protein measurement in veterinary clinical chemistry. Vet Res 35:163–187
Pösö AR (2002) Monocarboxylate transporters and lactate metabolism in equine athletes: a review. Acta Vet Scand 43:63–74
Schneider A, Corrêa MN, Butler WR (2013) Acute phase proteins in Holstein cows diagnosed with uterine infection. Res Vet Sci 95:269–271
Tennent-Brown BS (2012) Interpreting lactate measurement in critically ill horses: diagnosis, treatment, and prognosis. Compend Contin Educ Pract Vet 34:E2
Tharwat M, Al-Sobayil F, Buczinski S (2013a) Effect of racing on the serum concentrations of cardiac troponin I and creatine kinase myocardial band in racing camels (Camelus dromedarius). Vet Res Commun 37:139–144
Tharwat M, Al-Sobayil F, Buczinski S (2013b) Cardiac biomarkers changes in camels (Camelus dromedarius) secondary to long road transportation. J Vet Cardiol 15:15–22
Yazwinski M, Milizio JG, Wakshlag JJ (2013) Assessment of serum myokines and markers of inflammation associated with exercise in endurance racing sled dogs. J Vet Intern Med 27:371–376
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The authors thank N. Peachy, Professor of English, Qassim University, Saudi Arabia, for language revisions.
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The work was performed at the Veterinary Teaching Hospital, College of Agriculture and Veterinary Medicine, Qassim University.
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Tharwat, M., Al-Sobayil, F. The impact of racing on serum concentrations of acute-phase proteins in racing dromedary camels. Comp Clin Pathol 24, 575–579 (2015). https://doi.org/10.1007/s00580-014-1948-0
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DOI: https://doi.org/10.1007/s00580-014-1948-0