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Pathological changes associated with experimental 900-MHz electromagnetic wave exposure in rats

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Abstract

The aim of this study was to determine a possible relationship between whole-body 900-MHz Global System for Mobile Communication-like electromagnetic field (GSM-EMF) exposure and pathological changes in vital organs of Sprague–Dawley rats. Twenty adult male rats were used in four equal independent groups—control (without EMF) and low-, moderate-, and high-exposure groups—according to the time of exposure to EMF (1, 2, and 4 h). The exposure was performed for 30 consecutive days. Tissue samples of the heart, liver, and left kidney were collected and fixed in 10 % buffered formalin for histopathological examination. Some pathological lesions, especially in the kidney (congestion and inflammation) were seen. Our results demonstrate that the use of GSM-like EMF at these intensities and duration can induce pathological lesions in the heart, liver, or kidney, but these are not EMF specific.

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Acknowledgment

Thanks are due to Dr. Mahjoob Vahedi and all the staff of the Laboratory Animal Center, Shiraz University of Medical Sciences, Shiraz, Iran for their help in providing and keeping the normal mature rats.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Biochemistry, School of Veterinary Medicine, Shiraz University, P.O. Box 71345-1731, Shiraz, Iran

    Masood Sepehrimanesh, Mahdi Saeb & Nasrin Kazemipour

  2. Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Negar Azarpira

  3. Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran

    Saeed Nazifi

  4. Laboratory Animal Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Omid Koohi

Authors
  1. Masood Sepehrimanesh
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  2. Negar Azarpira
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  3. Mahdi Saeb
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  4. Saeed Nazifi
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  5. Nasrin Kazemipour
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  6. Omid Koohi
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Corresponding author

Correspondence to Masood Sepehrimanesh.

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Sepehrimanesh, M., Azarpira, N., Saeb, M. et al. Pathological changes associated with experimental 900-MHz electromagnetic wave exposure in rats. Comp Clin Pathol 23, 1629–1631 (2014). https://doi.org/10.1007/s00580-013-1835-0

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  • DOI: https://doi.org/10.1007/s00580-013-1835-0

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